Progression through mitosis promotes PARP inhibitor-induced cytotoxicity in homologous recombination-deficient cancer cells 著者: Schoonen, P, Talens, F, Stok, C, Gogola, E, Heijink, A, Bouwman, P, Foijer, F, Tarsounas, M, Blatter, S, Jonkers, J, Rottenberg, S, van Vugt, M

A high-throughput pharmaceutical screen identifies compounds with specific toxicity against BRCA2-deficient tumors. 著者: Evers, B, Schut, E, van der Burg, E, Braumuller, T, Egan, D, Holstege, H, Edser, P, Adams, D, Wade-Martins, R, Bouwman, P, Jonkers, J

BRCA2 acts as a RAD51 loader to facilitate telomere replication and capping. 著者: Badie, S, Escandell, J, Bouwman, P, Carlos, A, Thanasoula, M, Gallardo, M, Suram, A, Jaco, I, Benitez, J, Herbig, U, Blasco, M, Jonkers, J, Tarsounas, M

53BP1 loss rescues BRCA1 deficiency and is associated with triple-negative and BRCA-mutated breast cancers. 著者: Bouwman, P, Aly, A, Escandell, J, Pieterse, M, Bartkova, J, van der Gulden, H, Hiddingh, S, Thanasoula, M, Kulkarni, A, Yang, Q, Haffty, BG, Tommiska, J, Blomqvist, C, Drapkin, R, Adams, D, Nevanlinna, H, Bartek, J, Tarsounas, M, Ganesan, S, Jonkers, J

BRCA1 and BRCA2 tumor suppressors protect against endogenous acetaldehyde toxicity. 著者: Tacconi, E, Lai, X, Folio, C, Porru, M, Zonderland, G, Badie, S, Michl, J, Sechi, I, Rogier, M, Matía García, V, Batra, A, Rueda, O, Bouwman, P, Jonkers, J, Ryan, A, Reina-San-Martin, B, Hui, J, Tang, N, Bruna, A, Biroccio, A, Tarsounas, M