Bradley Hyman

Bradley Theodore Hyman is currently John B. Penney, Jr. Professor of Neurology at Harvard Medical School and Director of the Massachusetts Alzheimer Disease Research Center and Memory Disorder Unit at Massachusetts General Hospital. He was educated at Northwestern University (BA Chemistry, 1977) and the University of Iowa (PhD; MD). He was awarded the Metlife Foundation Award for Medical Research in Alzheimer's Disease in 2001 and the Potamkin Prize in 2006, together with Karen Duff and Karen Ashe. Provided by Wikipedia
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  1. 1
    RNA aptamer probes as optical imaging agents for the detection of amyloid plaques.

    RNA aptamer probes as optical imaging agents for the detection of amyloid plaques. by Christian T Farrar, Christopher M William, Eloise Hudry, Tadafumi Hashimoto, Bradley T Hyman

    Published 2014-01-01
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  2. 2
    Astrocyte tau deposition in progressive supranuclear palsy is associated with dysregulation of MAPT transcription

    Astrocyte tau deposition in progressive supranuclear palsy is associated with dysregulation of MAPT transcription by Rosemary J. Jackson, Alexandra Melloni, Dustin P. Fykstra, Alberto Serrano-Pozo, Leslie Shinobu, Bradley T. Hyman

    Published 2024-08-01
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  3. 3
    Aqueous extractable nonfibrillar and sarkosyl extractable fibrillar Alzheimer’s disease tau seeds have distinct properties

    Aqueous extractable nonfibrillar and sarkosyl extractable fibrillar Alzheimer’s disease tau seeds have distinct properties by Anastasie Mate de Gerando, Anita Khasnavis, Lindsay A. Welikovitch, Harshil Bhavsar, Calina Glynn, Noe Quittot, Romain Perbet, Bradley T. Hyman

    Published 2024-09-01
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  4. 4
    A Nuclear Magnetic Resonance Spectroscopy Method in Characterization of Blood Metabolomics for Alzheimer’s Disease

    A Nuclear Magnetic Resonance Spectroscopy Method in Characterization of Blood Metabolomics for Alzheimer’s Disease by JianXiang Weng, Isabella H. Muti, Anya B. Zhong, Pia Kivisäkk, Bradley T. Hyman, Steven E. Arnold, Leo L. Cheng

    Published 2022-02-01
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  5. 5
    Tissue libraries enable rapid determination of conditions that preserve antibody labeling in cleared mouse and human tissue

    Tissue libraries enable rapid determination of conditions that preserve antibody labeling in cleared mouse and human tissue by Theodore J Zwang, Rachel E Bennett, Maria Lysandrou, Benjamin Woost, Anqi Zhang, Charles M Lieber, Douglas S Richardson, Bradley T Hyman

    Published 2023-01-01
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  6. 6
    Specific detection of tau seeding activity in Alzheimer’s disease using rationally designed biosensor cells

    Specific detection of tau seeding activity in Alzheimer’s disease using rationally designed biosensor cells by Aurelien Lathuiliere, Youhwa Jo, Romain Perbet, Cameron Donahue, Caitlin Commins, Noé Quittot, Zhanyun Fan, Rachel E. Bennett, Bradley T. Hyman

    Published 2023-08-01
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  7. 7
    Rate of tau propagation is a heritable disease trait in genetically diverse mouse strains

    Rate of tau propagation is a heritable disease trait in genetically diverse mouse strains by Lindsay A. Welikovitch, Simon Dujardin, Amy R. Dunn, Analiese R. Fernandes, Anita Khasnavis, Lori B. Chibnik, Catherine C. Kaczorowski, Bradley T. Hyman

    Published 2023-02-01
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  8. 8
    Cyclic multiplex fluorescent immunohistochemistry and machine learning reveal distinct states of astrocytes and microglia in normal aging and Alzheimer’s disease

    Cyclic multiplex fluorescent immunohistochemistry and machine learning reveal distinct states of astrocytes and microglia in normal aging and Alzheimer’s disease by Clara Muñoz-Castro, Ayush Noori, Colin G. Magdamo, Zhaozhi Li, Jordan D. Marks, Matthew P. Frosch, Sudeshna Das, Bradley T. Hyman, Alberto Serrano-Pozo

    Published 2022-02-01
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  9. 9
    Cholinergic modulation of hippocampal calcium activity across the sleep-wake cycle

    Cholinergic modulation of hippocampal calcium activity across the sleep-wake cycle by Heng Zhou, Kevin R Neville, Nitsan Goldstein, Shushi Kabu, Naila Kausar, Rong Ye, Thuan Tinh Nguyen, Noah Gelwan, Bradley T Hyman, Stephen N Gomperts

    Published 2019-03-01
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  10. 10
    VWA3A-derived ependyma promoter drives increased therapeutic protein secretion into the CSF

    VWA3A-derived ependyma promoter drives increased therapeutic protein secretion into the CSF by Ellie M. Carrell, Yong Hong Chen, Paul T. Ranum, Stephanie L. Coffin, Larry N. Singh, Luis Tecedor, Megan S. Keiser, Eloise Hudry, Bradley T. Hyman, Beverly L. Davidson

    Published 2023-09-01
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  11. 11
    Interneuron diversity in the human dorsal striatum

    Interneuron diversity in the human dorsal striatum by Leonardo D. Garma, Lisbeth Harder, Juan M. Barba-Reyes, Sergio Marco Salas, Mónica Díez-Salguero, Mats Nilsson, Alberto Serrano-Pozo, Bradley T. Hyman, Ana B. Muñoz-Manchado

    Published 2024-07-01
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  12. 12
    Differential regulation of brain microvessel transcriptome and brain metabolome by western and heart-healthy dietary patterns in Ossabaw pigs

    Differential regulation of brain microvessel transcriptome and brain metabolome by western and heart-healthy dietary patterns in Ossabaw pigs by Gloria Solano-Aguilar, Gregory Matuszek, Nirupa R. Matthan, Alice H. Lichtenstein, Xuedi Wang, Sukla Lakshman, Kathryn Barger, Joseph F. Urban, Aleksey Molokin, Rachel E. Bennett, Bradley T. Hyman, Stefania Lamon-Fava

    Published 2024-11-01
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  13. 13
    Neurofibrillary tangle-bearing neurons have reduced risk of cell death in mice with Alzheimer’s pathology

    Neurofibrillary tangle-bearing neurons have reduced risk of cell death in mice with Alzheimer’s pathology by Theodore J. Zwang, Eric del Sastre, Nina Wolf, Nancy Ruiz-Uribe, Benjamin Woost, Zachary Hoglund, Zhanyun Fan, Joshua Bailey, Lois Nfor, Luc Buée, K. Peter R. Nilsson, Bradley T. Hyman, Rachel E. Bennett

    Published 2024-08-01
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  14. 14
    The G51D SNCA mutation generates a slowly progressive α-synuclein strain in early-onset Parkinson’s disease

    The G51D SNCA mutation generates a slowly progressive α-synuclein strain in early-onset Parkinson’s disease by Heather H. C. Lau, Ivan Martinez-Valbuena, Raphaella W. L. So, Surabhi Mehra, Nicholas R. G. Silver, Alison Mao, Erica Stuart, Cian Schmitt-Ulms, Bradley T. Hyman, Martin Ingelsson, Gabor G. Kovacs, Joel C. Watts

    Published 2023-05-01
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  15. 15
    Size matters: the impact of nucleus size on results from spatial transcriptomics

    Size matters: the impact of nucleus size on results from spatial transcriptomics by Elyas Mohammadi, Katarzyna Chojnowska, Michał Bieńkowski, Anna Kostecka, Magdalena Koczkowska, Michał A. Żmijewski, Marcin Jąkalski, Martin Ingelsson, Natalia Filipowicz, Paweł Olszewski, Hanna Davies, Justyna M. Wierzbicka, Bradley T. Hyman, Jan P. Dumanski, Arkadiusz Piotrowski, Jakub Mieczkowski

    Published 2023-04-01
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  16. 16
    Causal inference in medical records and complementary systems pharmacology for metformin drug repurposing towards dementia

    Causal inference in medical records and complementary systems pharmacology for metformin drug repurposing towards dementia by Marie-Laure Charpignon, Bella Vakulenko-Lagun, Bang Zheng, Colin Magdamo, Bowen Su, Kyle Evans, Steve Rodriguez, Artem Sokolov, Sarah Boswell, Yi-Han Sheu, Melek Somai, Lefkos Middleton, Bradley T. Hyman, Rebecca A. Betensky, Stan N. Finkelstein, Roy E. Welsch, Ioanna Tzoulaki, Deborah Blacker, Sudeshna Das, Mark W. Albers

    Published 2022-12-01
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  17. 17
    Development and Evaluation of a Natural Language Processing Annotation Tool to Facilitate Phenotyping of Cognitive Status in Electronic Health Records: Diagnostic Study

    Development and Evaluation of a Natural Language Processing Annotation Tool to Facilitate Phenotyping of Cognitive Status in Electronic Health Records: Diagnostic Study by Ayush Noori, Colin Magdamo, Xiao Liu, Tanish Tyagi, Zhaozhi Li, Akhil Kondepudi, Haitham Alabsi, Emily Rudmann, Douglas Wilcox, Laura Brenner, Gregory K Robbins, Lidia Moura, Sahar Zafar, Nicole M Benson, John Hsu, John R Dickson, Alberto Serrano-Pozo, Bradley T Hyman, Deborah Blacker, M Brandon Westover, Shibani S Mukerji, Sudeshna Das

    Published 2022-08-01
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  18. 18
    Plasma biomarkers for diagnosis of Alzheimer's disease and prediction of cognitive decline in individuals with mild cognitive impairment

    Plasma biomarkers for diagnosis of Alzheimer's disease and prediction of cognitive decline in individuals with mild cognitive impairment by Pia Kivisäkk, Becky C. Carlyle, Becky C. Carlyle, Thadryan Sweeney, Bianca A. Trombetta, Kathryn LaCasse, Leena El-Mufti, Idil Tuncali, Lori B. Chibnik, Lori B. Chibnik, Sudeshna Das, Clemens R. Scherzer, Keith A. Johnson, Bradford C. Dickerson, Teresa Gomez-Isla, Deborah Blacker, Derek H. Oakley, Matthew P. Frosch, Bradley T. Hyman, Anahit Aghvanyan, Pradeepthi Bathala, Christopher Campbell, George Sigal, Martin Stengelin, Steven E. Arnold

    Published 2023-03-01
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  19. 19
    Machine learning of dissection photographs and surface scanning for quantitative 3D neuropathology

    Machine learning of dissection photographs and surface scanning for quantitative 3D neuropathology by Harshvardhan Gazula, Henry FJ Tregidgo, Benjamin Billot, Yael Balbastre, Jonathan Williams-Ramirez, Rogeny Herisse, Lucas J Deden-Binder, Adria Casamitjana, Erica J Melief, Caitlin S Latimer, Mitchell D Kilgore, Mark Montine, Eleanor Robinson, Emily Blackburn, Michael S Marshall, Theresa R Connors, Derek H Oakley, Matthew P Frosch, Sean I Young, Koen Van Leemput, Adrian V Dalca, Bruce Fischl, Christine L MacDonald, C Dirk Keene, Bradley T Hyman, Juan E Iglesias

    Published 2024-06-01
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  20. 20
    Author Correction: [11C]Martinostat PET analysis reveals reduced HDAC I availability in Alzheimer’s disease

    Author Correction: [11C]Martinostat PET analysis reveals reduced HDAC I availability in Alzheimer’s disease by Tharick A. Pascoal, Mira Chamoun, Elad Lax, Hsiao-Ying Wey, Monica Shin, Kok Pin Ng, Min Su Kang, Sulantha Mathotaarachchi, Andrea L. Benedet, Joseph Therriault, Firoza Z. Lussier, Frederick A. Schroeder, Jonathan M. DuBois, Baileigh G. Hightower, Tonya M. Gilbert, Nicole R. Zürcher, Changning Wang, Robert Hopewell, Mallar Chakravarty, Melissa Savard, Emilie Thomas, Sara Mohaddes, Sarah Farzin, Alyssa Salaciak, Stephanie Tullo, A. Claudio Cuello, Jean-Paul Soucy, Gassan Massarweh, Heungsun Hwang, Eliane Kobayashi, Bradley T. Hyman, Bradford C. Dickerson, Marie-Christine Guiot, Moshe Szyf, Serge Gauthier, Jacob M. Hooker, Pedro Rosa-Neto

    Published 2022-10-01
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