583 Novel, potent, and selective inhibitors of hypoxia-inducible factor (HIF)-2α reverse pro-tumorigenic transcriptional programming in cancer, stromal, and immune cells by Matthew Walters, Stephen Young, Ada Chen, Akshata Udyavar, Kelsey Sivick Gauthier, Dana Piovesan, Kenneth Lawson, Soonweng Cho, Jean Chan, Jennie Au, Cesar Meleza, Xiaoning Zhao, Anh Tran, Samuel Drew, Balint Gal, Brandon Rosen, Manmohan Leleti, Elaine Ginn, Lixia Jin, Jay Powers