Genomic risk scores and oral contraceptive-associated ischemic stroke risk: a call for collaboration Autor Forrest Lin, Liisa Tomppo, Brady Gaynor, Kathleen Ryan, John W. Cole, John W. Cole, Braxton D. Mitchell, Braxton D. Mitchell, Jukka Putaala, Steven J. Kittner

Získat plný text

Extension of GWAS results for lipid-related phenotypes to extreme obesity using electronic health record (EHR) data and the Metabochip. Autor Ankita eParihar, G. Craig eWood, Xin eChu, Qunjan eJin, George eArgyropoulos, Christopher D. Still, Alan eShuldiner, Alan eShuldiner, Braxton D Mitchell, Braxton D Mitchell, Glenn S. Gerhard

Získat plný text

Disruption of ldlr causes increased LDL-c and vascular lipid accumulation in a zebrafish model of hypercholesterolemia[S] Autor Elizabeth A. O'Hare, Xiaochun Wang, May E. Montasser, Yen-Pei C. Chang, Braxton D. Mitchell, Norann A. Zaghloul

Získat plný text

Associations of genome-wide and regional autozygosity with 96 complex traits in old order Amish Autor Megan T. Lynch, Kristin A. Maloney, Huichun Xu, James A. Perry, Regeneron Genetics Center, Alan R. Shuldiner, Braxton D. Mitchell

Získat plný text

Acute pharmacodynamic responses to sitagliptin: Drug‐induced increase in early insulin secretion in oral glucose tolerance test Autor Amber L. Beitelshees, Elizabeth A. Streeten, Zhinous Shahidzadeh Yazdi, Hilary B. Whitlatch, Braxton D. Mitchell, Alan R. Shuldiner, May E. Montasser, Simeon I. Taylor

Získat plný text

Genome-wide meta-analysis identified novel variant associated with hallux valgus in Caucasians Autor Liubov Arbeeva, Michelle Yau, Braxton D. Mitchell, Rebecca D. Jackson, Kathleen Ryan, Yvonne M. Golightly, Marian T. Hannan, Amanda Nelson, Joanne M. Jordan, Marc C. Hochberg

Získat plný text

Gender differences in first and secondhand smoke exposure, spirometric lung function and cardiometabolic health in the old order Amish: A novel population without female smoking. Autor Robert M Reed, Mark T Dransfield, Michael Eberlein, Michael Miller, Giora Netzer, Mary Pavlovich, Toni I Pollin, Steven M Scharf, Alan R Shuldiner, Don Sin, Braxton D Mitchell

Získat plný text

Evidence of survival bias in the association between APOE-Є4 and age at ischemic stroke onset Autor Joanna von Berg, Joanna von Berg, Patrick F. McArdle, Paavo Häppölä, Jeffrey Haessler, Charles Kooperberg, Robin Lemmens, Robin Lemmens, Alessandro Pezzini, Alessandro Pezzini, Vincent Thijs, Vincent Thijs, Vincent Thijs, Sara L. Pulit, Steven J. Kittner, Steven J. Kittner, Braxton D. Mitchell, Braxton D. Mitchell, Jeroen de Ridder, Jeroen de Ridder, Sander W. van der Laan, Sander W. van der Laan

Získat plný text

Clopidogrel Improves Skin Microcirculatory Endothelial Function in Persons With Heightened Platelet Aggregation Autor Shabnam Salimi, Joshua P. Lewis, Laura M. Yerges‐Armstrong, Braxton D. Mitchell, Faisal Saeed, Jeffry R. O'Connell, James A. Perry, Kathleen A. Ryan, Alan R. Shuldiner, Afshin Parsa

Získat plný text

Missense variants in SORT1 are associated with LDL-C in an Amish population Autor Kelly A. Mitok, Kathryn L. Schueler, Sarah M. King, Joseph Orr, Kathleen A. Ryan, Mark P. Keller, Ronald M. Krauss, Braxton D. Mitchell, Alan R. Shuldiner, Alan D. Attie

Získat plný text

Randomized evaluation of the loss‐of‐function carboxylesterase 1 (CES1) G143E variant on clopidogrel and ticagrelor pharmacodynamics Autor Joshua P. Lewis, Kathleen A. Ryan, Elizabeth A. Streeten, Hilary B. Whitlatch, Melanie Daue, Keith Tanner, James A. Perry, Jeffrey R. O'Connell, Alan R. Shuldiner, Braxton D. Mitchell

Získat plný text

Living the good life? Mortality and hospital utilization patterns in the Old Order Amish. Autor Braxton D Mitchell, Woei-Jyh Lee, Magdalena I Tolea, Kelsey Shields, Zahra Ashktorab, Laurence S Magder, Kathleen A Ryan, Toni I Pollin, Patrick F McArdle, Alan R Shuldiner, Alejandro A Schäffer

Získat plný text

Selective adipocyte loss of Angiopoietin-2 prompts female-specific obesity and metabolic syndrome Autor Bin Ni, Shanshan Chen, Kathleen A. Ryan, Michael L. Maitland, Jared S. Farrar, Martin Witzenrath, Birgitt Gubier, Cindy Serdjebi, Karine Bertotti, Rui Wang, Fadi N. Salloum, Luigi Marino, Braxton D. Mitchell, Francesco S. Celi

Získat plný text

Circulating CD34+ Cell Count is Associated with Extent of Subclinical Atherosclerosis in Asymptomatic Amish Men, Independent of 10-Year Framingham Risk Autor Lawrence F. Bielak D.D.S., M.P.H., Richard B. Horenstein, Kathleen A. Ryan, Patrick F. Sheedy, John A. Rumberger, Keith Tanner, Wendy Post, Braxton D. Mitchell, Alan R. Shuldiner, Patricia A. Peyser

Získat plný text

Prevalence, control, and treatment of diabetes, hypertension, and high cholesterol in the Amish Autor Shisi He, Kathleen A Ryan, Elizabeth A Streeten, Patrick F McArdle, Melanie Daue, Donna Trubiano, Yvonne Rohrer, Patrick Donnelly, Maryann Drolet, Sylvia Newcomer, Susan Shaub, Nancy Weitzel, Toni I Pollin, Braxton D Mitchell

Získat plný text

Bitter taste receptors influence glucose homeostasis. Autor Cedrick D Dotson, Lan Zhang, Hong Xu, Yu-Kyong Shin, Stephan Vigues, Sandra H Ott, Amanda E T Elson, Hyun Jin Choi, Hillary Shaw, Josephine M Egan, Braxton D Mitchell, Xiaodong Li, Nanette I Steinle, Steven D Munger

Získat plný text

Rare variants in ischemic stroke: an exome pilot study. Autor John W Cole, O Colin Stine, Xinyue Liu, Abhishek Pratap, Yuching Cheng, Luke J Tallon, Lisa K Sadzewicz, Nicole Dueker, Marcella A Wozniak, Barney J Stern, James F Meschia, Braxton D Mitchell, Steven J Kittner, Jeffrey R O'Connell

Získat plný text

Analysis of the gut microbiota in the old order Amish and its relation to the metabolic syndrome. Autor Margaret L Zupancic, Brandi L Cantarel, Zhenqiu Liu, Elliott F Drabek, Kathleen A Ryan, Shana Cirimotich, Cheron Jones, Rob Knight, William A Walters, Daniel Knights, Emmanuel F Mongodin, Richard B Horenstein, Braxton D Mitchell, Nanette Steinle, Soren Snitker, Alan R Shuldiner, Claire M Fraser

Získat plný text

An exome-wide sequencing study of lipid response to high-fat meal and fenofibrate in Caucasians from the GOLDN cohort Autor Xin Geng, Marguerite R. Irvin, Bertha Hidalgo, Stella Aslibekyan, Vinodh Srinivasasainagendra, Ping An, Alexis C. Frazier-Wood, Hemant K. Tiwari, Tushar Dave, Kathleen Ryan, Jose M. Ordovas, Robert J. Straka, Mary F. Feitosa, Paul N. Hopkins, Ingrid Borecki, Michael A. Province, Braxton D. Mitchell, Donna K. Arnett, Degui Zhi

Získat plný text

An Exome-Wide Sequencing Study of the GOLDN Cohort Reveals Novel Associations of Coding Variants and Fasting Plasma Lipids Autor Xin Geng, Xin Geng, Marguerite R. Irvin, Bertha Hidalgo, Stella Aslibekyan, Vinodh Srinivasasainagendra, Ping An, Alexis C. Frazier-Wood, Hemant K. Tiwari, Tushar Dave, Kathleen Ryan, Jose M. Ordovas, Jose M. Ordovas, Jose M. Ordovas, Robert J. Straka, Mary F. Feitosa, Paul N. Hopkins, Ingrid Borecki, Michael A. Province, Braxton D. Mitchell, Donna K. Arnett, Degui Zhi, Degui Zhi

Získat plný text