Genomic risk scores and oral contraceptive-associated ischemic stroke risk: a call for collaboration gan Forrest Lin, Liisa Tomppo, Brady Gaynor, Kathleen Ryan, John W. Cole, John W. Cole, Braxton D. Mitchell, Braxton D. Mitchell, Jukka Putaala, Steven J. Kittner

Cael y testun llawn

Extension of GWAS results for lipid-related phenotypes to extreme obesity using electronic health record (EHR) data and the Metabochip. gan Ankita eParihar, G. Craig eWood, Xin eChu, Qunjan eJin, George eArgyropoulos, Christopher D. Still, Alan eShuldiner, Alan eShuldiner, Braxton D Mitchell, Braxton D Mitchell, Glenn S. Gerhard

Cael y testun llawn

Disruption of ldlr causes increased LDL-c and vascular lipid accumulation in a zebrafish model of hypercholesterolemia[S] gan Elizabeth A. O'Hare, Xiaochun Wang, May E. Montasser, Yen-Pei C. Chang, Braxton D. Mitchell, Norann A. Zaghloul

Cael y testun llawn

Associations of genome-wide and regional autozygosity with 96 complex traits in old order Amish gan Megan T. Lynch, Kristin A. Maloney, Huichun Xu, James A. Perry, Regeneron Genetics Center, Alan R. Shuldiner, Braxton D. Mitchell

Cael y testun llawn

Acute pharmacodynamic responses to sitagliptin: Drug‐induced increase in early insulin secretion in oral glucose tolerance test gan Amber L. Beitelshees, Elizabeth A. Streeten, Zhinous Shahidzadeh Yazdi, Hilary B. Whitlatch, Braxton D. Mitchell, Alan R. Shuldiner, May E. Montasser, Simeon I. Taylor

Cael y testun llawn

Genome-wide meta-analysis identified novel variant associated with hallux valgus in Caucasians gan Liubov Arbeeva, Michelle Yau, Braxton D. Mitchell, Rebecca D. Jackson, Kathleen Ryan, Yvonne M. Golightly, Marian T. Hannan, Amanda Nelson, Joanne M. Jordan, Marc C. Hochberg

Cael y testun llawn

Gender differences in first and secondhand smoke exposure, spirometric lung function and cardiometabolic health in the old order Amish: A novel population without female smoking. gan Robert M Reed, Mark T Dransfield, Michael Eberlein, Michael Miller, Giora Netzer, Mary Pavlovich, Toni I Pollin, Steven M Scharf, Alan R Shuldiner, Don Sin, Braxton D Mitchell

Cael y testun llawn

Evidence of survival bias in the association between APOE-Є4 and age at ischemic stroke onset gan Joanna von Berg, Joanna von Berg, Patrick F. McArdle, Paavo Häppölä, Jeffrey Haessler, Charles Kooperberg, Robin Lemmens, Robin Lemmens, Alessandro Pezzini, Alessandro Pezzini, Vincent Thijs, Vincent Thijs, Vincent Thijs, Sara L. Pulit, Steven J. Kittner, Steven J. Kittner, Braxton D. Mitchell, Braxton D. Mitchell, Jeroen de Ridder, Jeroen de Ridder, Sander W. van der Laan, Sander W. van der Laan

Cael y testun llawn

Clopidogrel Improves Skin Microcirculatory Endothelial Function in Persons With Heightened Platelet Aggregation gan Shabnam Salimi, Joshua P. Lewis, Laura M. Yerges‐Armstrong, Braxton D. Mitchell, Faisal Saeed, Jeffry R. O'Connell, James A. Perry, Kathleen A. Ryan, Alan R. Shuldiner, Afshin Parsa

Cael y testun llawn

Missense variants in SORT1 are associated with LDL-C in an Amish population gan Kelly A. Mitok, Kathryn L. Schueler, Sarah M. King, Joseph Orr, Kathleen A. Ryan, Mark P. Keller, Ronald M. Krauss, Braxton D. Mitchell, Alan R. Shuldiner, Alan D. Attie

Cael y testun llawn

Randomized evaluation of the loss‐of‐function carboxylesterase 1 (CES1) G143E variant on clopidogrel and ticagrelor pharmacodynamics gan Joshua P. Lewis, Kathleen A. Ryan, Elizabeth A. Streeten, Hilary B. Whitlatch, Melanie Daue, Keith Tanner, James A. Perry, Jeffrey R. O'Connell, Alan R. Shuldiner, Braxton D. Mitchell

Cael y testun llawn

Living the good life? Mortality and hospital utilization patterns in the Old Order Amish. gan Braxton D Mitchell, Woei-Jyh Lee, Magdalena I Tolea, Kelsey Shields, Zahra Ashktorab, Laurence S Magder, Kathleen A Ryan, Toni I Pollin, Patrick F McArdle, Alan R Shuldiner, Alejandro A Schäffer

Cael y testun llawn

Selective adipocyte loss of Angiopoietin-2 prompts female-specific obesity and metabolic syndrome gan Bin Ni, Shanshan Chen, Kathleen A. Ryan, Michael L. Maitland, Jared S. Farrar, Martin Witzenrath, Birgitt Gubier, Cindy Serdjebi, Karine Bertotti, Rui Wang, Fadi N. Salloum, Luigi Marino, Braxton D. Mitchell, Francesco S. Celi

Cael y testun llawn

Circulating CD34+ Cell Count is Associated with Extent of Subclinical Atherosclerosis in Asymptomatic Amish Men, Independent of 10-Year Framingham Risk gan Lawrence F. Bielak D.D.S., M.P.H., Richard B. Horenstein, Kathleen A. Ryan, Patrick F. Sheedy, John A. Rumberger, Keith Tanner, Wendy Post, Braxton D. Mitchell, Alan R. Shuldiner, Patricia A. Peyser

Cael y testun llawn

Prevalence, control, and treatment of diabetes, hypertension, and high cholesterol in the Amish gan Shisi He, Kathleen A Ryan, Elizabeth A Streeten, Patrick F McArdle, Melanie Daue, Donna Trubiano, Yvonne Rohrer, Patrick Donnelly, Maryann Drolet, Sylvia Newcomer, Susan Shaub, Nancy Weitzel, Toni I Pollin, Braxton D Mitchell

Cael y testun llawn

Bitter taste receptors influence glucose homeostasis. gan Cedrick D Dotson, Lan Zhang, Hong Xu, Yu-Kyong Shin, Stephan Vigues, Sandra H Ott, Amanda E T Elson, Hyun Jin Choi, Hillary Shaw, Josephine M Egan, Braxton D Mitchell, Xiaodong Li, Nanette I Steinle, Steven D Munger

Cael y testun llawn

Rare variants in ischemic stroke: an exome pilot study. gan John W Cole, O Colin Stine, Xinyue Liu, Abhishek Pratap, Yuching Cheng, Luke J Tallon, Lisa K Sadzewicz, Nicole Dueker, Marcella A Wozniak, Barney J Stern, James F Meschia, Braxton D Mitchell, Steven J Kittner, Jeffrey R O'Connell

Cael y testun llawn

Analysis of the gut microbiota in the old order Amish and its relation to the metabolic syndrome. gan Margaret L Zupancic, Brandi L Cantarel, Zhenqiu Liu, Elliott F Drabek, Kathleen A Ryan, Shana Cirimotich, Cheron Jones, Rob Knight, William A Walters, Daniel Knights, Emmanuel F Mongodin, Richard B Horenstein, Braxton D Mitchell, Nanette Steinle, Soren Snitker, Alan R Shuldiner, Claire M Fraser

Cael y testun llawn

An exome-wide sequencing study of lipid response to high-fat meal and fenofibrate in Caucasians from the GOLDN cohort gan Xin Geng, Marguerite R. Irvin, Bertha Hidalgo, Stella Aslibekyan, Vinodh Srinivasasainagendra, Ping An, Alexis C. Frazier-Wood, Hemant K. Tiwari, Tushar Dave, Kathleen Ryan, Jose M. Ordovas, Robert J. Straka, Mary F. Feitosa, Paul N. Hopkins, Ingrid Borecki, Michael A. Province, Braxton D. Mitchell, Donna K. Arnett, Degui Zhi

Cael y testun llawn

An Exome-Wide Sequencing Study of the GOLDN Cohort Reveals Novel Associations of Coding Variants and Fasting Plasma Lipids gan Xin Geng, Xin Geng, Marguerite R. Irvin, Bertha Hidalgo, Stella Aslibekyan, Vinodh Srinivasasainagendra, Ping An, Alexis C. Frazier-Wood, Hemant K. Tiwari, Tushar Dave, Kathleen Ryan, Jose M. Ordovas, Jose M. Ordovas, Jose M. Ordovas, Robert J. Straka, Mary F. Feitosa, Paul N. Hopkins, Ingrid Borecki, Michael A. Province, Braxton D. Mitchell, Donna K. Arnett, Degui Zhi, Degui Zhi

Cael y testun llawn