Genomic risk scores and oral contraceptive-associated ischemic stroke risk: a call for collaboration Bằng Forrest Lin, Liisa Tomppo, Brady Gaynor, Kathleen Ryan, John W. Cole, John W. Cole, Braxton D. Mitchell, Braxton D. Mitchell, Jukka Putaala, Steven J. Kittner

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Extension of GWAS results for lipid-related phenotypes to extreme obesity using electronic health record (EHR) data and the Metabochip. Bằng Ankita eParihar, G. Craig eWood, Xin eChu, Qunjan eJin, George eArgyropoulos, Christopher D. Still, Alan eShuldiner, Alan eShuldiner, Braxton D Mitchell, Braxton D Mitchell, Glenn S. Gerhard

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Disruption of ldlr causes increased LDL-c and vascular lipid accumulation in a zebrafish model of hypercholesterolemia[S] Bằng Elizabeth A. O'Hare, Xiaochun Wang, May E. Montasser, Yen-Pei C. Chang, Braxton D. Mitchell, Norann A. Zaghloul

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Associations of genome-wide and regional autozygosity with 96 complex traits in old order Amish Bằng Megan T. Lynch, Kristin A. Maloney, Huichun Xu, James A. Perry, Regeneron Genetics Center, Alan R. Shuldiner, Braxton D. Mitchell

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Acute pharmacodynamic responses to sitagliptin: Drug‐induced increase in early insulin secretion in oral glucose tolerance test Bằng Amber L. Beitelshees, Elizabeth A. Streeten, Zhinous Shahidzadeh Yazdi, Hilary B. Whitlatch, Braxton D. Mitchell, Alan R. Shuldiner, May E. Montasser, Simeon I. Taylor

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Genome-wide meta-analysis identified novel variant associated with hallux valgus in Caucasians Bằng Liubov Arbeeva, Michelle Yau, Braxton D. Mitchell, Rebecca D. Jackson, Kathleen Ryan, Yvonne M. Golightly, Marian T. Hannan, Amanda Nelson, Joanne M. Jordan, Marc C. Hochberg

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Gender differences in first and secondhand smoke exposure, spirometric lung function and cardiometabolic health in the old order Amish: A novel population without female smoking. Bằng Robert M Reed, Mark T Dransfield, Michael Eberlein, Michael Miller, Giora Netzer, Mary Pavlovich, Toni I Pollin, Steven M Scharf, Alan R Shuldiner, Don Sin, Braxton D Mitchell

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Evidence of survival bias in the association between APOE-Є4 and age at ischemic stroke onset Bằng Joanna von Berg, Joanna von Berg, Patrick F. McArdle, Paavo Häppölä, Jeffrey Haessler, Charles Kooperberg, Robin Lemmens, Robin Lemmens, Alessandro Pezzini, Alessandro Pezzini, Vincent Thijs, Vincent Thijs, Vincent Thijs, Sara L. Pulit, Steven J. Kittner, Steven J. Kittner, Braxton D. Mitchell, Braxton D. Mitchell, Jeroen de Ridder, Jeroen de Ridder, Sander W. van der Laan, Sander W. van der Laan

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Clopidogrel Improves Skin Microcirculatory Endothelial Function in Persons With Heightened Platelet Aggregation Bằng Shabnam Salimi, Joshua P. Lewis, Laura M. Yerges‐Armstrong, Braxton D. Mitchell, Faisal Saeed, Jeffry R. O'Connell, James A. Perry, Kathleen A. Ryan, Alan R. Shuldiner, Afshin Parsa

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Missense variants in SORT1 are associated with LDL-C in an Amish population Bằng Kelly A. Mitok, Kathryn L. Schueler, Sarah M. King, Joseph Orr, Kathleen A. Ryan, Mark P. Keller, Ronald M. Krauss, Braxton D. Mitchell, Alan R. Shuldiner, Alan D. Attie

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Randomized evaluation of the loss‐of‐function carboxylesterase 1 (CES1) G143E variant on clopidogrel and ticagrelor pharmacodynamics Bằng Joshua P. Lewis, Kathleen A. Ryan, Elizabeth A. Streeten, Hilary B. Whitlatch, Melanie Daue, Keith Tanner, James A. Perry, Jeffrey R. O'Connell, Alan R. Shuldiner, Braxton D. Mitchell

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Living the good life? Mortality and hospital utilization patterns in the Old Order Amish. Bằng Braxton D Mitchell, Woei-Jyh Lee, Magdalena I Tolea, Kelsey Shields, Zahra Ashktorab, Laurence S Magder, Kathleen A Ryan, Toni I Pollin, Patrick F McArdle, Alan R Shuldiner, Alejandro A Schäffer

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Selective adipocyte loss of Angiopoietin-2 prompts female-specific obesity and metabolic syndrome Bằng Bin Ni, Shanshan Chen, Kathleen A. Ryan, Michael L. Maitland, Jared S. Farrar, Martin Witzenrath, Birgitt Gubier, Cindy Serdjebi, Karine Bertotti, Rui Wang, Fadi N. Salloum, Luigi Marino, Braxton D. Mitchell, Francesco S. Celi

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Circulating CD34+ Cell Count is Associated with Extent of Subclinical Atherosclerosis in Asymptomatic Amish Men, Independent of 10-Year Framingham Risk Bằng Lawrence F. Bielak D.D.S., M.P.H., Richard B. Horenstein, Kathleen A. Ryan, Patrick F. Sheedy, John A. Rumberger, Keith Tanner, Wendy Post, Braxton D. Mitchell, Alan R. Shuldiner, Patricia A. Peyser

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Prevalence, control, and treatment of diabetes, hypertension, and high cholesterol in the Amish Bằng Shisi He, Kathleen A Ryan, Elizabeth A Streeten, Patrick F McArdle, Melanie Daue, Donna Trubiano, Yvonne Rohrer, Patrick Donnelly, Maryann Drolet, Sylvia Newcomer, Susan Shaub, Nancy Weitzel, Toni I Pollin, Braxton D Mitchell

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Bitter taste receptors influence glucose homeostasis. Bằng Cedrick D Dotson, Lan Zhang, Hong Xu, Yu-Kyong Shin, Stephan Vigues, Sandra H Ott, Amanda E T Elson, Hyun Jin Choi, Hillary Shaw, Josephine M Egan, Braxton D Mitchell, Xiaodong Li, Nanette I Steinle, Steven D Munger

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Rare variants in ischemic stroke: an exome pilot study. Bằng John W Cole, O Colin Stine, Xinyue Liu, Abhishek Pratap, Yuching Cheng, Luke J Tallon, Lisa K Sadzewicz, Nicole Dueker, Marcella A Wozniak, Barney J Stern, James F Meschia, Braxton D Mitchell, Steven J Kittner, Jeffrey R O'Connell

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Analysis of the gut microbiota in the old order Amish and its relation to the metabolic syndrome. Bằng Margaret L Zupancic, Brandi L Cantarel, Zhenqiu Liu, Elliott F Drabek, Kathleen A Ryan, Shana Cirimotich, Cheron Jones, Rob Knight, William A Walters, Daniel Knights, Emmanuel F Mongodin, Richard B Horenstein, Braxton D Mitchell, Nanette Steinle, Soren Snitker, Alan R Shuldiner, Claire M Fraser

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An exome-wide sequencing study of lipid response to high-fat meal and fenofibrate in Caucasians from the GOLDN cohort Bằng Xin Geng, Marguerite R. Irvin, Bertha Hidalgo, Stella Aslibekyan, Vinodh Srinivasasainagendra, Ping An, Alexis C. Frazier-Wood, Hemant K. Tiwari, Tushar Dave, Kathleen Ryan, Jose M. Ordovas, Robert J. Straka, Mary F. Feitosa, Paul N. Hopkins, Ingrid Borecki, Michael A. Province, Braxton D. Mitchell, Donna K. Arnett, Degui Zhi

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An Exome-Wide Sequencing Study of the GOLDN Cohort Reveals Novel Associations of Coding Variants and Fasting Plasma Lipids Bằng Xin Geng, Xin Geng, Marguerite R. Irvin, Bertha Hidalgo, Stella Aslibekyan, Vinodh Srinivasasainagendra, Ping An, Alexis C. Frazier-Wood, Hemant K. Tiwari, Tushar Dave, Kathleen Ryan, Jose M. Ordovas, Jose M. Ordovas, Jose M. Ordovas, Robert J. Straka, Mary F. Feitosa, Paul N. Hopkins, Ingrid Borecki, Michael A. Province, Braxton D. Mitchell, Donna K. Arnett, Degui Zhi, Degui Zhi

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