Assessment of ferroptosis as a promising candidate for metastatic uveal melanoma treatment and prognostication by Ellie Swords, Ellie Swords, Breandán N. Kennedy, Breandán N. Kennedy, Valentina Tonelotto, Valentina Tonelotto

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The potential of small molecule brain-derived neurotrophic factor: mimetics to treat inherited retinal degeneration by Andrea Cerquone Perpetuini, Justine Mathoux, Breandán N Kennedy

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Affordable and effective optokinetic response methods to assess visual acuity and contrast sensitivity in larval to juvenile zebrafish [version 2; peer review: 2 approved] by Alicia Gómez Sánchez, Basilio Colligris, Yolanda Álvarez, Breandán N. Kennedy

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Orthogonal Drug Pooling Enhances Phenotype-Based Discovery of Ocular Antiangiogenic Drugs in Zebrafish Larvae by Nils Ohnesorge, Temitope Sasore, Daniel Hillary, Yolanda Alvarez, Michelle Carey, Breandán N. Kennedy

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Genetic Deletion of Zebrafish Rab28 Causes Defective Outer Segment Shedding, but Not Retinal Degeneration by Stephen P. Carter, Stephen P. Carter, Ailís L. Moran, Ailís L. Moran, David Matallanas, Gavin J. McManus, Oliver E. Blacque, Oliver E. Blacque, Breandán N. Kennedy, Breandán N. Kennedy

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Enhancing Understanding of the Visual Cycle by Applying CRISPR/Cas9 Gene Editing in Zebrafish by Rebecca Ward, Husvinee Sundaramurthi, Husvinee Sundaramurthi, Husvinee Sundaramurthi, Valeria Di Giacomo, Breandán N. Kennedy

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Selective Histone Deacetylase 6 Inhibitors Restore Cone Photoreceptor Vision or Outer Segment Morphology in Zebrafish and Mouse Models of Retinal Blindness by Husvinee Sundaramurthi, Husvinee Sundaramurthi, Husvinee Sundaramurthi, Husvinee Sundaramurthi, Sarah L. Roche, Guinevere L. Grice, Ailis Moran, Ailis Moran, Eugene T. Dillion, Eugene T. Dillion, Giuseppe Campiani, James A. Nathan, Breandán N. Kennedy, Breandán N. Kennedy

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Neuroprotective Nanoparticles Targeting the Retina: A Polymeric Platform for Ocular Drug Delivery Applications by Patrizia Colucci, Martina Giannaccini, Matteo Baggiani, Breandán N. Kennedy, Luciana Dente, Vittoria Raffa, Chiara Gabellini

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Systemic treatment with cigarette smoke extract affects zebrafish visual behaviour, intraocular vasculature morphology and outer segment phagocytosis [version 2; peer review: 2 app... by Alicia Gómez Sánchez, Ailis Moran, Patrizia Colucci, Basilio Colligris, Breandán N. Kennedy, Alexandro Moya López, Yolanda Álvarez

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The Role of Mitochondria in Optic Atrophy With Autosomal Inheritance by Elin L. Strachan, Elin L. Strachan, Delphi Mac White-Begg, Delphi Mac White-Begg, John Crean, John Crean, John Crean, Alison L. Reynolds, Alison L. Reynolds, Breandán N. Kennedy, Breandán N. Kennedy, Niamh C. O’Sullivan, Niamh C. O’Sullivan

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Selective inhibition of retinal angiogenesis by targeting PI3 kinase. by Yolanda Alvarez, Olaya Astudillo, Lasse Jensen, Alison L Reynolds, Nora Waghorne, Derek P Brazil, Yihai Cao, John J O'Connor, Breandán N Kennedy

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Characterisation of an Isogenic Model of Cisplatin Resistance in Oesophageal Adenocarcinoma Cells by Amy M. Buckley, Becky AS. Bibby, Margaret R. Dunne, Susan A. Kennedy, Maria B. Davern, Breandán N. Kennedy, Stephen G. Maher, Jacintha O’Sullivan

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Curcumin Sensitizes Kidney Cancer Cells to TRAIL-Induced Apoptosis via ROS Mediated Activation of JNK-CHOP Pathway and Upregulation of DR4 by Ismael Obaidi, Hilary Cassidy, Verónica Ibáñez Gaspar, Jasmin McCaul, Michael Higgins, Melinda Halász, Alison L. Reynolds, Breandan N. Kennedy, Tara McMorrow

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Ciliary Rab28 and the BBSome negatively regulate extracellular vesicle shedding by Jyothi S Akella, Stephen P Carter, Ken Nguyen, Sofia Tsiropoulou, Ailis L Moran, Malan Silva, Fatima Rizvi, Breandan N Kennedy, David H Hall, Maureen M Barr, Oliver E Blacque

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1,4-dihydroxy quininib modulates the secretome of uveal melanoma tumour explants and a marker of oxidative phosphorylation in a metastatic xenograft model by Kayleigh Slater, Kayleigh Slater, Rosa Bosch, Kaelin Francis Smith, Kaelin Francis Smith, Chowdhury Arif Jahangir, Chowdhury Arif Jahangir, Sandra Garcia-Mulero, Sandra Garcia-Mulero, Arman Rahman, Arman Rahman, Fiona O’Connell, Josep M. Piulats, Valerie O’Neill, Noel Horgan, Sarah E. Coupland, Jacintha O’Sullivan, William M. Gallagher, William M. Gallagher, Alberto Villanueva, Alberto Villanueva, Breandán N. Kennedy, Breandán N. Kennedy

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Dysregulated miR-125a promotes angiogenesis through enhanced glycolysisResearch in context by Sarah M. Wade, Nils Ohnesorge, Hayley McLoughlin, Monika Biniecka, Steven P. Carter, Michelle Trenkman, Clare C. Cunningham, Trudy McGarry, Mary Canavan, Breandán N. Kennedy, Douglas J. Veale, Ursula Fearon

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Whole-Organism Developmental Expression Profiling Identifies RAB-28 as a Novel Ciliary GTPase Associated with the BBSome and Intraflagellar Transport. by Victor L Jensen, Stephen Carter, Anna A W M Sanders, Chunmei Li, Julie Kennedy, Tiffany A Timbers, Jerry Cai, Noemie Scheidel, Breandán N Kennedy, Ryan D Morin, Michel R Leroux, Oliver E Blacque

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Combining 1,4-dihydroxy quininib with Bevacizumab/FOLFOX alters angiogenic and inflammatory secretions in ex vivo colorectal tumors by Susan A. Kennedy, Maria E. Morrissey, Margaret R. Dunne, Fiona O’Connell, Clare T. Butler, Mary-Clare Cathcart, Amy M. Buckley, Brian J. Mehigan, John O. Larkin, Paul McCormick, Breandán N. Kennedy, Jacintha O’Sullivan

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1,4-dihydroxy quininib activates ferroptosis pathways in metastatic uveal melanoma and reveals a novel prognostic biomarker signature by Valentina Tonelotto, Marcel Costa-Garcia, Eve O’Reilly, Kaelin Francis Smith, Kayleigh Slater, Eugene T. Dillon, Marzia Pendino, Catherine Higgins, Paola Sist, Rosa Bosch, Sabina Passamonti, Josep M. Piulats, Alberto Villanueva, Federica Tramer, Luca Vanella, Michelle Carey, Breandán N. Kennedy

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Inhibition of the Pim1 oncogene results in diminished visual function. by Jun Yin, Lisa Shine, Francis Raycroft, Sudhakar Deeti, Alison Reynolds, Kristin M Ackerman, Antonino Glaviano, Sean O'Farrell, Olivia O'Leary, Claire Kilty, Ciaran Kennedy, Sarah McLoughlin, Megan Rice, Eileen Russell, Desmond G Higgins, David R Hyde, Breandan N Kennedy

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