Showing 1 - 8 results of 8 for search 'Brendan D Manning', query time: 0.03s Refine Results
  1. 1
    Therapeutic trial of metformin and bortezomib in a mouse model of tuberous sclerosis complex (TSC).

    Therapeutic trial of metformin and bortezomib in a mouse model of tuberous sclerosis complex (TSC). by Neil Auricchio, Izabela Malinowska, Reuben Shaw, Brendan D Manning, David J Kwiatkowski

    Published 2012-01-01
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  2. 2
    The mTORC1 Signaling Network Senses Changes in Cellular Purine Nucleotide Levels

    The mTORC1 Signaling Network Senses Changes in Cellular Purine Nucleotide Levels by Gerta Hoxhaj, James Hughes-Hallett, Rebecca C. Timson, Erika Ilagan, Min Yuan, John M. Asara, Issam Ben-Sahra, Brendan D. Manning

    Published 2017-10-01
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  3. 3
    The mTORC1-mediated activation of ATF4 promotes protein and glutathione synthesis downstream of growth signals

    The mTORC1-mediated activation of ATF4 promotes protein and glutathione synthesis downstream of growth signals by Margaret E Torrence, Michael R MacArthur, Aaron M Hosios, Alexander J Valvezan, John M Asara, James R Mitchell, Brendan D Manning

    Published 2021-03-01
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  4. 4
    Hepatic mTORC1 signaling activates ATF4 as part of its metabolic response to feeding and insulin

    Hepatic mTORC1 signaling activates ATF4 as part of its metabolic response to feeding and insulin by Vanessa Byles, Yann Cormerais, Krystle Kalafut, Victor Barrera, James E. Hughes Hallett, Shannan Ho Sui, John M. Asara, Christopher M. Adams, Gerta Hoxhaj, Issam Ben-Sahra, Brendan D. Manning

    Published 2021-11-01
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  5. 5
    The non-essential TSC complex component TBC1D7 restricts tissue mTORC1 signaling and brain and neuron growth

    The non-essential TSC complex component TBC1D7 restricts tissue mTORC1 signaling and brain and neuron growth by Sandra Schrötter, Christopher J. Yuskaitis, Michael R. MacArthur, Sarah J. Mitchell, Aaron M. Hosios, Maria Osipovich, Margaret E. Torrence, James R. Mitchell, Gerta Hoxhaj, Mustafa Sahin, Brendan D. Manning

    Published 2022-05-01
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  6. 6
    Reciprocal effects of mTOR inhibitors on pro-survival proteins dictate therapeutic responses in tuberous sclerosis complex

    Reciprocal effects of mTOR inhibitors on pro-survival proteins dictate therapeutic responses in tuberous sclerosis complex by Molly C. McNamara, Aaron M. Hosios, Margaret E. Torrence, Ting Zhao, Cameron Fraser, Meghan Wilkinson, David J. Kwiatkowski, Elizabeth P. Henske, Chin-Lee Wu, Kristopher A. Sarosiek, Alexander J. Valvezan, Brendan D. Manning

    Published 2022-11-01
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  7. 7
    Akt-mTORC1 signaling regulates Acly to integrate metabolic input to control of macrophage activation

    Akt-mTORC1 signaling regulates Acly to integrate metabolic input to control of macrophage activation by Anthony J Covarrubias, Halil Ibrahim Aksoylar, Jiujiu Yu, Nathaniel W Snyder, Andrew J Worth, Shankar S Iyer, Jiawei Wang, Issam Ben-Sahra, Vanessa Byles, Tiffany Polynne-Stapornkul, Erika C Espinosa, Dudley Lamming, Brendan D Manning, Yijing Zhang, Ian A Blair, Tiffany Horng

    Published 2016-02-01
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  8. 8
    Purine nucleotide depletion prompts cell migration by stimulating the serine synthesis pathway

    Purine nucleotide depletion prompts cell migration by stimulating the serine synthesis pathway by Mona Hoseini Soflaee, Rushendhiran Kesavan, Umakant Sahu, Alpaslan Tasdogan, Elodie Villa, Zied Djabari, Feng Cai, Diem H. Tran, Hieu S. Vu, Eunus S. Ali, Halie Rion, Brendan P. O’Hara, Sherwin Kelekar, James Hughes Hallett, Misty Martin, Thomas P. Mathews, Peng Gao, John M. Asara, Brendan D. Manning, Issam Ben-Sahra, Gerta Hoxhaj

    Published 2022-05-01
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