Editorial: New therapeutics for soft tissue sarcomas by Marla Weetall, Mark Rance, Matthew Ingham, Brian A. Van Tine, Brian A. Van Tine, Brian A. Van Tine

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Pathogenesis and Current Treatment of Osteosarcoma: Perspectives for Future Therapies by Richa Rathore, Brian A. Van Tine

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Therapeutic arginine starvation in ASS1-deficient cancers inhibits the Warburg effect by Jeff C. Kremer, Brian A. Van Tine

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Common Pitfalls in Ewing Sarcoma and Desmoplastic Small Round Cell Tumor Diagnosis Seen in a Study of 115 Cases by Nikolaos A. Trikalinos, John S. A. Chrisinger, Brian A. Van Tine

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Intensity modulated radiation therapy and surgery for Management of Retroperitoneal Sarcomas: a single-institution experience by Pippa F. Cosper, Jeffrey Olsen, Todd DeWees, Brian A. Van Tine, William Hawkins, Jeff Michalski, Imran Zoberi

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A phase II clinical study of 13‐deoxy, 5‐iminodoxorubicin (GPX‐150) with metastatic and unresectable soft tissue sarcoma by Brian A. Van Tine, Mark Agulnik, Richard D. Olson, Gerald M. Walsh, Arthur Klausner, Nicole E. Frank, Todd T. Talley, Mohammed M. Milhem

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Systemic Anti-Cancer Therapy in Synovial Sarcoma: A Systematic Review by Richard F. Riedel, Robin L. Jones, Antoine Italiano, Chet Bohac, Juliette C. Thompson, Kerstin Mueller, Zaeem Khan, Seth M. Pollack, Brian A. Van Tine

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The novel drug candidate S2/IAPinh improves survival in models of pancreatic and ovarian cancer by Takaomi Hagi, Suwanna Vangveravong, Rony Takchi, Qingqing Gong, S. Peter Goedegebuure, Herve Tiriac, Brian A. Van Tine, Matthew A. Powell, William G. Hawkins, Dirk Spitzer

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A Retrospective Multi-Institutional Cohort Analysis of Clinical Characteristics and Outcomes in Dedifferentiated Chondrosarcoma by Nam Bui, Hilary Dietz, Sheima Farag, Angela C. Hirbe, Michael J. Wagner, Brian A. Van Tine, Kristen Ganjoo, Robin L. Jones, Vicki L. Keedy, Elizabeth J. Davis

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Pregnancy outcomes related to the treatment of sarcomas with anthracyclines and/or ifosfamide during pregnancy by Devon Miller, John A. Livingston, Yeonhee Park, Kristi Posey, Sonia Godbole, Keith Skubitz, Steven I. Robinson, Mark Agulnik, Lara E. Davis, Brian A. Van Tine, Angela C. Hirbe, Amanda Parkes

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Pharmacokinetics of doxorubicin following concomitant intravenous administration of olaratumab (IMC‐3G3) to patients with advanced soft tissue sarcoma by Victor M. Villalobos, Gary Mo, Mark Agulnik, Seth M. Pollack, Daniel A. Rushing, Arun Singh, Brian A. Van Tine, Rhian McNaughton, Rodney L. Decker, Wei Zhang, Ashwin Shahir, Damien M. Cronier

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Clinical outcomes of patients with advanced synovial sarcoma or myxoid/round cell liposarcoma treated at major cancer centers in the United States by Seth M. Pollack, Neeta Somaiah, Dejka M. Araujo, Mihaela Druta, Brian A. Van Tine, Melissa A. Burgess, Sant P. Chawla, Mahesh Seetharam, Scott H. Okuno, Chet Bohac, Michael Chen, Sergey Yurasov, Steven Attia

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Quality of life of patients with soft tissue sarcoma treated with doxorubicin in the ANNOUNCE phase III clinical trial by Brian A Van Tine MD, PhD, Anders Krarup-Hansen MD, PhD, Lisa M Hess PhD, Albiruni R Abdul Razak MD, Victoria Soldatenkova MSc, Jennifer Wright MD, Se Hoon Park MD

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Pharmacokinetics of dacarbazine and unesbulin and CYP1A2‐mediated drug interactions in patients with leiomyosarcoma by Lan Gao, Diksha Kaushik, Brian A. Van Tine, Matthew A. Ingham, Steven Attia, Christian F. Meyer, Gary K. Schwartz, Pius Maliakal, John D. Baird, Jiyuan Ma, Rosemary Barrett, Dhiren D'Silva, Kylie O'Keefe, Ronald Kong

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A Retrospective Analysis of the Efficacy of Immunotherapy in Metastatic Soft-Tissue Sarcomas by Varun Monga, Keith M. Skubitz, Seth Maliske, Sarah L. Mott, Hilary Dietz, Angela C. Hirbe, Brian A. Van Tine, Peter Oppelt, Scott Okuno, Steven Robinson, Madeline O’Connor, Mahesh Seetharam, Steven Attia, John Charlson, Mark Agulnik, Mohammed Milhem

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Cardiac safety of trabectedin monotherapy or in combination with pegylated liposomal doxorubicin in patients with sarcomas and ovarian cancer by Robin L. Jones, Thomas J. Herzog, Shreyaskumar R. Patel, Margaret von Mehren, Scott M. Schuetze, Brian A. Van Tine, Robert L. Coleman, Roland Knoblauch, Spyros Triantos, Peter Hu, Waleed Shalaby, Tracy McGowan, Bradley J. Monk, George D. Demetri

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Phase II study of dacarbazine given with modern prophylactic anti-emetics and growth factor support to patients with metastatic, resistant soft tissue, and bone sarcoma by Brian A Van Tine, Mia C Weiss, Angela C Hirbe, Peter J Oppelt, Sarah Abaricia, Kathryn Trinkaus, Jingqin Luo, Shellie Berry, Tyler Ruff, Cheryl Callahan, Jacqui Toensikoetter, Jessica Ley, Marilyn J Siegel, Farrokh Dehdashti, Barry A Siegel, Douglas R Adkins

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Unmet Medical Needs and Future Perspectives for Leiomyosarcoma Patients—A Position Paper from the National LeioMyoSarcoma Foundation (NLMSF) and Sarcoma Patients EuroNet (SPAEN) by Bernd Kasper, Annie Achee, Kathrin Schuster, Roger Wilson, Gerard van Oortmerssen, Rebecca A. Gladdy, Matthew L. Hemming, Paul Huang, Matthew Ingham, Robin L. Jones, Seth M. Pollack, Denise Reinke, Roberta Sanfilippo, Scott M. Schuetze, Neeta Somaiah, Brian A. Van Tine, Breelyn Wilky, Scott Okuno, Jonathan Trent

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Biomarker correlates with response to NY-ESO-1 TCR T cells in patients with synovial sarcoma by Alexandra Gyurdieva, Stefan Zajic, Ya-Fang Chang, E. Andres Houseman, Shan Zhong, Jaegil Kim, Michael Nathenson, Thomas Faitg, Mary Woessner, David C. Turner, Aisha N. Hasan, John Glod, Rosandra N. Kaplan, Sandra P. D’Angelo, Dejka M. Araujo, Warren A. Chow, Mihaela Druta, George D. Demetri, Brian A. Van Tine, Stephan A. Grupp, Gregg D. Fine, Ioanna Eleftheriadou

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Systemic and local immunity following adoptive transfer of NY-ESO-1 SPEAR T cells in synovial sarcoma by Indu Ramachandran, Daniel E. Lowther, Rebecca Dryer-Minnerly, Ruoxi Wang, Svetlana Fayngerts, Daniel Nunez, Gareth Betts, Natalie Bath, Alex J. Tipping, Luca Melchiori, Jean-Marc Navenot, John Glod, Crystal L. Mackall, Sandra P. D’Angelo, Dejka M. Araujo, Warren A. Chow, George D. Demetri, Mihaela Druta, Brian A. Van Tine, Stephan A. Grupp, Albiruni R. Abdul Razak, Breelyn Wilky, Malini Iyengar, Trupti Trivedi, Erin Van Winkle, Karen Chagin, Rafael Amado, Gwendolyn K. Binder, Samik Basu

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