Growth factors and lipid transport in early mammalian development od Brice, A

Mapping the uncertainties in internet-based clinical trials: a systematic review and qualitative study od Brice, A

Accumulating research: a systematic account of how cumulative meta-analyses would have provided knowledge, improved health, reduced harm and saved resources od Clarke, M, Brice, A, Chalmers, I

Creating a database of internet-based clinical trials to support a public-led research programme: A descriptive analysis od Brice, A, Price, A, Burls, A

Self-management open online trials in health [SMOOTH] an analysis of existing online trials [Protocol] od Price, A, Burls, A, Vasanthan, L, Clarke, M, Liew, S, Brice, A

Self-Management Open Online Trials in Health (SMOOTH): Methods and public involvement survey of corresponding authors of existing online trials od Price, A, Vasanthan, L, Clarke, M, Liew, S, Brice, A, Burls, A

Taking healthcare interventions from trial to practice. od Glasziou, P, Chalmers, I, Altman, D, Bastian, H, Boutron, I, Brice, A, Jamtvedt, G, Farmer, A, Ghersi, D, Groves, T, Heneghan, C, Hill, S, Lewin, S, Michie, S, Perera, R, Pomeroy, V, Tilson, J, Shepperd, S, Williams, J

From trial to practice Authors' reply od Glasziou, P, Chalmers, I, Altman, D, Bastian, H, Boutron, I, Brice, A, Jamtvedt, G, Farmer, A, Ghersi, D, Groves, T, Heneghan, C, Hill, S, Lewin, S, Michie, S, Perera, R, Pomeroy, V, Tilson, J, Shepperd, S, Williams, J

Cross-talking noncoding RNAs contribute to cell-specific neurodegeneration in SCA7. od Tan, J, Vance, K, Varela, M, Sirey, T, Watson, L, Curtis, H, Marinello, M, Alves, S, Steinkraus, B, Cooper, S, Nesterova, T, Brockdorff, N, Fulga, T, Brice, A, Sittler, A, Oliver, P, Wood, M, Ponting, C, Marques, A

Taking healthcare interventions from trial to practice. od Glasziou, P, Chalmers, I, Altman, D, Bastian, H, Boutron, I, Brice, A, Jamtvedt, G, Farmer, A, Ghersi, D, Groves, T, Heneghan, C, Hill, S, Lewin, S, Michie, S, Perera, R, Pomeroy, V, Tilson, J, Shepperd, S, Williams, J

DNM3 and genetic modifiers of age of onset in LRRK2 Gly2019Ser parkinsonism: a genome-wide linkage and association study od Parkkinen, L, Trinh, J, Gustavsson, E, Vilariño-Güell, C, Bortnick, S, Latourelle, J, McKenzie, M, Tu, C, Nosova, E, Khinda, J, Milnerwood, A, Lesage, S, Brice, A, Tazir, M, Aasly, J, Haytural, H, Foroud, T, Myers, R, Ben Sassi, S, Hentati, E, Nabli, F, Farhat, E, Amouri, R, Hentati, F, Farrer, M

Using genome-wide complex trait analysis to quantify 'missing heritability' in Parkinson's disease. od Keller, M, Saad, M, Bras, J, Bettella, F, Nicolaou, N, Simón-Sánchez, J, Mittag, F, Büchel, F, Sharma, M, Gibbs, JR, Schulte, C, Moskvina, V, Durr, A, Holmans, P, Kilarski, L, Guerreiro, R, Hernandez, D, Brice, A, Ylikotila, P, Stefánsson, H, Majamaa, K, Morris, H, Williams, N, Gasser, T, Heutink, P

Discovery and functional prioritization of Parkinson’s disease candidate genes from large-scale whole exome sequencing od Jansen, IE, Ye, H, Heetveld, S, Lechler, MC, Michels, H, Seinstra, RI, Lubbe, SJ, Drouet, V, Lesage, S, Majounie, E, Gibbs, JR, Nalls, MA, Ryten, M, Botia, JA, Vandrovcova, J, Simon-Sanchez, J, Castillo-Lizardo, M, Rizzu, P, Blauwendraat, C, Chouhan, AK, Li, Y, Yogi, P, Amin, N, Van Duijn, CM, Morris, HR, Brice, A, Singleton, AB, David, DC, Nollen, EA, Jain, S, Shulman, JM, Heutink, P

Genome-wide Pleiotropy Between Parkinson Disease and Autoimmune Diseases od Witoelar, A, Jansen, IE, Wang, Y, Desikan, RS, Gibbs, JR, Blauwendraat, C, Thompson, WK, Hernandez, DG, Djurovic, S, Schork, AJ, Bettella, F, Ellinghaus, D, Franke, A, Lie, BA, McEvoy, LK, Karlsen, TH, Lesage, S, Morris, HR, Brice, A, Wood, NW, Heutink, P, Hardy, J, Singleton, AB, Dale, AM, Gasser, T, Andreassen, OA, Sharma, M, International Parkinson’s Disease Genomics Consortium (IPDGC), North American Brain Expression Consortium (NABEC), and United Kingdom Brain Expression Consortium (UKBEC) Investigators

Large-scale meta-analysis of genome-wide association data identifies six new risk loci for Parkinson's disease od Nalls, M, Pankratz, N, Lill, C, Do, C, Hernandez, D, Saad, M, DeStefano, A, Kara, E, Bras, J, Sharma, M, Schulte, C, Keller, M, Arepalli, S, Letson, C, Edsall, C, Stefansson, H, Liu, X, Pliner, H, Lee, J, Cheng, R, Ikram, M, Ioannidis, J, Hadjigeorgiou, G, Bis, J, Martinez, M, Perlmutter, J, Goate, A, Marder, K, Fiske, B, Sutherland, M, Xiromerisiou, G, Myers, R, Clark, L, Stefansson, K, Hardy, J, Heutink, P, Chen, H, Wood, N, Houlden, H, Payami, H, Brice, A, Scott, W, Gasser, T, Bertram, L, Eriksson, N, Foroud, T, Singleton, A

A Two-Stage Meta-Analysis Identifies Several New Loci for Parkinson's Disease od Plagnol, V, Nalls, M, Bras, J, Hernandez, D, Sharma, M, Sheerin, U, Saad, M, Simon-Sanchez, J, Schulte, C, Lesage, S, Sveinbjornsdottir, S, Amouyel, P, Arepalli, S, Band, G, Barker, R, Bellinguez, C, Ben-Shlomo, Y, Berendse, H, Berg, D, Bhatia, K, de Bie, R, Biffi, A, Bloem, B, Bochdanovits, Z, Bonin, M, Brockmann, K, Brooks, J, Burn, D, Charlesworth, G, Chen, H, Chinnery, P, Chong, S, Clarke, C, Cookson, MR, Cooper, J, Corvol, J, Counsell, C, Damier, P, Dartigues, J, Deloukas, P, Deuschl, G, Dexter, D, van Dijk, K, Dillman, A, Durif, F, Duerr, A, Edkins, S, Evans, JR, Foltynie, T, Freeman, C, Gao, J, Gardner, M, Gibbs, JR, Goate, A, Gray, E, Guerreiro, R, Gustafsson, O, Harris, C, Hellenthal, G, van Hilten, J, Hofman, A, Hollenbeck, A, Holton, J, Hu, M, Huang, X, Huber, H, Hudson, G, Hunt, SE, Huttenlocher, J, Illig, T, Jonsson, P, Langford, C, Lees, A, Lichtner, P, Limousin, P, Lopez, G, Lorenz, D, McNeill, A, Moorby, C, Moore, M, Morris, H, Morrison, K, Mudanohwo, E, O'Sullivan, S, Pearson, J, Pearson, R, Perlmutter, J, Petursson, H, Pirinen, M, Pollak, P, Post, B, Potter, S, Ravina, B, Revesz, T, Riess, O, Rivadeneira, F, Rizzu, P, Ryten, M, Sawcer, S, Schapira, A, Scheffer, H, Shaw, K, Shoulson, I, Sidransky, E, de Silva, R, Smith, C, Spencer, C, Stefansson, H, Steinberg, S, Stockton, J, Strange, A, Su, Z, Talbot, K, Tanner, C, Tashakkori-Ghanbaria, A, Tison, F, Trabzuni, D, Traynor, B, Uitterlinden, A, Vandrovcova, J, Velseboer, D, Vidailhet, M, Vukcevic, D, Walker, R, van de Warrenburg, B, Weale, M, Wickremaratchi, M, Williams, N, Williams-Gray, C, Winder-Rhodes, S, Stefansson, K, Martinez, M, Donnelly, P, Singleton, AB, Hardy, J, Heutink, P, Brice, A, Gasser, T, Wood, N, WTCCC2

Gene-wide analysis detects two new susceptibility genes for Alzheimer's disease od Escott-Price, V, Bellenguez, C, Wang, L, Choi, S, Harold, D, Jones, L, Holmans, P, Gerrish, A, Vedernikov, A, Richards, A, Destefano, A, Lambert, J, Ibrahim-Verbaas, C, Naj, A, Sims, R, Jun, G, Bis, J, Beecham, G, Grenier-Boley, B, Russo, G, Thornton-Wells, T, Denning, N, Smith, A, Chouraki, V, Thomas, C, Ikram, M, Zelenika, D, Vardarajan, B, Kamatani, Y, Lin, C, Schmidt, H, Kunkle, B, Dunstan, M, Vronskaya, M, Johnson, A, Ruiz, A, Bihoreau, M, Reitz, C, Pasquier, F, Hollingworth, P, Hanon, O, Fitzpatrick, A, Buxbaum, J, Campion, D, Crane, P, Baldwin, C, Becker, T, Gudnason, V, Cruchaga, C, Craig, D, Amin, N, Berr, C, Lopez, O, De Jager, P, Deramecourt, V, Johnston, J, Evans, D, Lovestone, S, Letenneur, L, Hernández, I, Rubinsztein, D, Eiriksdottir, G, Sleegers, K, Goate, A, Fiévet, N, Huentelman, M, Gill, M, Brown, K, Kamboh, M, Keller, L, Barberger-Gateau, P, McGuinness, B, Larson, E, Myers, A, Dufouil, C, Todd, S, Wallon, D, Love, S, Rogaeva, E, Gallacher, J, George-Hyslop, P, Clarimon, J, Lleo, A, Bayer, A, Tsuang, D, Yu, L, Tsolaki, M, Bossù, P, Spalletta, G, Proitsi, P, Collinge, J, Sorbi, S, Garcia, F, Fox, N, Hardy, J, Naranjo, M, Bosco, P, Clarke, R, Brayne, C, Galimberti, D, Scarpini, E, Bonuccelli, U, Mancuso, M, Siciliano, G, Moebus, S, Mecocci, P, Zompo, MD, Maier, W, Hampel, H, Pilotto, A, Frank-García, A, Panza, F, Solfrizzi, V, Caffarra, P, Nacmias, B, Perry, W, Mayhaus, M, Lannfelt, L, Hakonarson, H, Pichler, S, Carrasquillo, M, Ingelsson, M, Beekly, D, Alvarez, V, Zou, F, Valladares, O, Younkin, S, Coto, E, Hamilton-Nelson, K, Gu, W, Razquin, C, Pastor, P, Mateo, I, Owen, M, Faber, K, Jonsson, P, Combarros, O, O'Donovan, M, Cantwell, L, Soininen, H, Blacker, D, Mead, S, Mosley, T, Bennett, D, Harris, T, Fratiglioni, L, Holmes, C, De Bruijn, R, Passmore, P, Montine, T, Bettens, K, Rotter, J, Brice, A, Morgan, K, Foroud, T, Kukull, W, Hannequin, D, Powell, J, Nalls, M, Ritchie, K, Lunetta, K, Kauwe, J, Boerwinkle, E, Riemenschneider, M, Boada, M, Hiltunen, M, Martin, E, Schmidt, R, Rujescu, D, Dartigues, J, Mayeux, R, Tzourio, C, Hofman, A, Nöthen, M, Graff, C, Psaty, B, Haines, J, Lathrop, M, Pericak-Vance, M, Launer, L, Van Broeckhoven, C, Farrer, L, Van Duijn, C, Ramirez, A, Seshadri, S, Schellenberg, G, Amouyel, P, Williams, J

Genome-wide association analyses identify new risk variants and the genetic architecture of amyotrophic lateral sclerosis od Lin, K, Pulit, SL, Van Rheenen, W, Shatunov, A, Dekker, AM, McLaughlin, RL, Diekstra, FP, Van Der Spek, RAA, Võsa, U, De Jong, S, Robinson, MR, Yang, J, Fogh, I, Van Doormaal, PT, Tazelaar, GHP, Koppers, M, Blokhuis, AM, Sproviero, W, Jones, AR, Kenna, KP, Van Eijk, KR, Harschnitz, O, Schellevis, RD, Brands, WJ, Medic, J, Menelaou, A, Vajda, A, Ticozzi, N, Rogelj, B, Vrabec, K, Ravnik-Glavač, M, Koritnik, B, Zidar, J, Leonardis, L, Grošelj, LD, Millecamps, S, Salachas, F, Meininger, V, De Carvalho, M, Pinto, S, Mora, JS, Rojas-García, R, Polak, M, Chandran, S, Colville, S, Swingler, R, Morrison, KE, Shaw, PJ, Hardy, J, Orrell, RW, Pittman, A, Sidle, K, Fratta, P, Malaspina, A, Topp, S, Petri, S, Abdulla, S, Drepper, C, Sendtner, M, Meyer, T, Ophoff, RA, Staats, KA, Wiedau-Pazos, M, Lomen-Hoerth, C, Van Deerlin, VM, Trojanowski, JQ, Elman, L, McCluskey, L, Basak, AN, Tunca, C, Hamzeiy, H, Parman, Y, Meitinger, T, Lichtner, P, Radivojkov-Blagojevic, M, Andres, CR, Maurel, C, Bensimon, G, Landwehrmeyer, B, Brice, A, Payan, CAM, Saker-Delye, S, Dürr, A, Wood, NW, Tittmann, L, Lieb, W, Franke, A, Rietschel, M, Cichon, S, Nöthen, MM, Amouyel, P, Tzourio, C, Dartigues, J-F, Uitterlinden, AG, Rivadeneira, F, Estrada, K, Hofman, A, Curtis, C, Blauw, HM, Van Der Kooi, AJ, De Visser, M, Goris, A, Weber, M, Shaw, CE, Smith, BN, Pansarasa, O, Cereda, C, Del Bo, R, Comi, GP, D'Alfonso, S, Bertolin, C, Sorarù, G, Mazzini, L, Pensato, V, Gellera, C, Tiloca, C, Ratti, A, Calvo, A, Moglia, C, Brunetti, M, Arcuti, S, Capozzo, R, Zecca, C, Lunetta, C, Penco, S, Riva, N, Padovani, A, Filosto, M, Muller, B, Stuit, RJ, Registry, P, Slalom Group, Registry, S, Fals Sequencing Consortium, Slagen Consortium, Nnipps Study Group, Blair, I, Zhang, K, McCann, EP, Fifita, JA, Nicholson, GA, Rowe, DB, Pamphlett, R, Kiernan, MC, Grosskreutz, J, Witte, OW, Ringer, T, Prell, T, Stubendorff, B, Kurth, I, Hübner, CA, Leigh, PN, Casale, F, Chio, A, Beghi, E, Pupillo, E, Tortelli, R, Logroscino, G, Powell, J, Ludolph, AC, Weishaupt, JH, Robberecht, W, Van Damme, P, Franke, L, Pers, TH, Brown, RH, Glass, JD, Landers, JE, Hardiman, O, Andersen, PM, Corcia, P, Vourc'H, P, Silani, V, Wray, NR, Visscher, PM, De Bakker, PIW, Van Es, MA, Pasterkamp, RJ, Lewis, CM, Breen, G, Al-Chalabi, A, Van Den Berg, LH, Veldink, JH

Genome-wide analyses identify KIF5A as a novel ALS gene od Nicolas, A, Kenna, KP, Renton, AE, Ticozzi, N, Faghri, F, Chia, R, Dominov, JA, Kenna, BJ, Nalls, MA, Keagle, P, Rivera, AM, Van Rheenen, W, Murphy, NA, Van Vugt, JJFA, Geiger, JT, Van Der Spek, RA, Pliner, HA, Shankaracharya, Smith, BN, Marangi, G, Topp, SD, Abramzon, Y, Gkazi, AS, Eicher, JD, Kenna, A, Italsgen Consortium, Mora, G, Calvo, A, Mazzini, L, Riva, N, Mandrioli, J, Caponnetto, C, Battistini, S, Volanti, P, La Bella, V, Conforti, FL, Borghero, G, Messina, S, Simone, IL, Trojsi, F, Salvi, F, Logullo, FO, D'Alfonso, S, Corrado, L, Capasso, M, Ferrucci, L, Genomic Translation For ALS Care (GTAC) Consortium, Moreno, CDAM, Kamalakaran, S, Goldstein, DB, ALS Sequencing Consortium, Gitler, AD, Harris, T, Myers, RM, NYGC ALS Consortium, Phatnani, H, Musunuri, RL, Evani, US, Abhyankar, A, Zody, MC, Answer ALS Foundation, Kaye, J, Finkbeiner, S, Wyman, SK, Lenail, A, Lima, L, Fraenkel, E, Svendsen, CN, Thompson, LM, Van Eyk, JE, Berry, JD, Miller, TM, Kolb, SJ, Cudkowicz, M, Baxi, E, Clinical Research In ALS And Related Disorders For Therapeutic Development (CREATE) Consortium, Benatar, M, Taylor, JP, Rampersaud, E, Wu, G, Wuu, J, Slagen Consortium, Lauria, G, Verde, F, Fogh, I, Tiloca, C, Comi, GP, Sorarù, G, Cereda, C, French ALS Consortium, Corcia, P, Laaksovirta, H, Myllykangas, L, Jansson, L, Valori, M, Ealing, J, Hamdalla, H, Rollinson, S, Pickering-Brown, S, Orrell, RW, Sidle, KC, Malaspina, A, Hardy, J, Singleton, AB, Johnson, JO, Arepalli, S, Sapp, PC, McKenna-yasek, D, Polak, M, Asress, S, Al-Sarraj, S, King, A, Troakes, C, Vance, C, De Belleroche, J, Baas, F, Asbroek, ALMA, Muñoz-Blanco, JL, Hernandez, DG, Ding, J, Gibbs, JR, Scholz, SW, Floeter, MK, Campbell, RH, Landi, F, Bowser, R, Pulst, SM, Ravits, JM, Macgowan, DJL, Kirby, J, Pioro, EP, Pamphlett, R, Broach, J, Gerhard, G, Dunckley, TL, Brady, CB, Kowall, NW, Troncoso, JC, Le Ber, I, Mouzat, K, Lumbroso, S, Heiman-Patterson, TD, Kamel, F, Van Den Bosch, L, Baloh, RH, Strom, TM, Meitinger, T, Shatunov, A, Van Eijk, KR, De Carvalho, M, Kooyman, M, Middelkoop, B, Moisse, M, McLaughlin, RL, Van Es, MA, Weber, M, Boylan, KB, Van Blitterswijk, M, Rademakers, R, Morrison, KE, Basak, AN, Mora, JS, Drory, VE, Shaw, PJ, Turner, MR, Talbot, K, Hardiman, O, Williams, KL, Fifita, JA, Nicholson, GA, Blair, IP, Rouleau, GA, Esteban-Pérez, J, García-Redondo, A, Al-Chalabi, A, Project Mine ALS Sequencing Consortium, Rogaeva, E, Zinman, L, Ostrow, LW, Maragakis, NJ, Rothstein, JD, Simmons, Z, Cooper-Knock, J, Brice, A, Goutman, SA, Feldman, EL, Gibson, SB, Taroni, F, Ratti, A, Gellera, C, Van Damme, P, Robberecht, W, Fratta, P, Sabatelli, M, Lunetta, C, Ludolph, AC, Andersen, PM, Weishaupt, JH, Camu, W, Trojanowski, JQ, Van Deerlin, VM, Brown, RH, Van Den Berg, LH, Veldink, JH, Harms, MB, Glass, JD, Stone, DJ, Tienari, P, Silani, V, Chiò, A, Shaw, CE, Traynor, BJ, Landers, JE