Effect of levofloxacin on neutrophilic airway inflammation in stable COPD: a randomized, double-blind, placebo-controlled trial af Siva R, Bafadhel M, Monteiro W, Brightling CE, Pavord ID

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Long COVID research: an update from the PHOSP-COVID Scientific Summit af Brightling, CE, Evans, RA, Singapuri, A, Smith, N, Wain, LV, Sigfrid, LA

Investigating the role of pentraxin 3 as a biomarker for bacterial infection in subjects with COPD af Thulborn SJ, Dilpazir M, Haldar K, Mistry V, Brightling CE, Barer MR, Bafadhel M

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Sputum Moraxella catarrhalis strains exhibit diversity within and between COPD subjects af George LM, Haigh RD, Mistry V, Haldar K, Barer MR, Oggioni MR, Brightling CE

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S45 Evaluating the sensitivity and specificity of active neutrophil elastase as a biomarker for bacterial infection in subjects with copd af Thulborn, SJ, Akram, N, Mistry, V, Brightling, CE, Moffitt, K, Ribeiro, D, Bafadhel, M

Detection of Cell-Dissociated Non-Typeable Haemophilus influenzae in the Airways of Patients with Chronic Obstructive Pulmonary Disease af Thulborn SJ, Ceroni A, Haldar K, Mistry V, Cane JL, Brightling CE, Barer MR, Bafadhel M

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Airway bacteria measured by quantitative polymerase chain reaction and culture in patients with stable COPD: relationship with neutrophilic airway inflammation, exacerbation freque... af Bafadhel M, Haldar K, Barker B, Patel H, Mistry V, Barer MR, Pavord ID, Brightling CE

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Detection of cell-dissociated non-typeable haemophilus influenzae in the airways of patients with chronic obstructive pulmonary disease af Thulborn, SJ, Ceroni, A, Haldar, K, Mistry, V, Cane, JL, Brightling, CE, Barer, MR, Bafadhel, M

Cell-dissociated haemophilus influenzae and bacteria-associated inflammatory mediators in the airways of patients with chronic obstructive pulmonary disease af Thulborn, SJ, Ceroni, A, Haldar, K, Mistry, V, Cane, JL, Brightling, CE, Barer, MR, Bafadhel, M

The Prognostic Value of Blood Eosinophil Level in AECOPD is Influenced by Corticosteroid Treatment During Hospitalization af Li J, Liang L, Feng L, Cao S, Cai YS, Li X, Qian Z, Brightling CE, Tong Z

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Effect of Biologic Therapies on Airway Hyperresponsiveness and Allergic Response: A Systematic Literature Review af Spahn JD, Brightling CE, O’Byrne PM, Simpson LJ, Molfino NA, Ambrose CS, Martin N, Hallstrand TS

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Characterisation of exacerbations of severe eosinophilic asthma (SEA) on mepolizumab compared to placebo af Shrimanker, R, Hargaden, B, Bradding, P, Wardlaw, AJ, Brightling, CE, Green, R, Bafadhel, M, Pavord, ID, Haldar, P, Heaney, L

Blood Eosinophils and outcomes in severe hospitalized exacerbations of COPD af Bafadhel, M, Greening, NJ, Harvey-Dunstan, TC, Williams, JE, Morgan, MD, Brightling, CE, Hussain, SF, Pavord, ID, Singh, SJ, Steiner, MC

Systemic and pulmonary inflammation is independent of skeletal muscle changes in patients with chronic obstructive pulmonary disease af Barker BL, McKenna S, Mistry V, Pancholi M, Patel H, Haldar K, Barer MR, Pavord ID, Steiner MC, Brightling CE, Bafadhel M

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Microbiome balance in sputum determined by PCR stratifies COPD exacerbations and shows potential for selective use of antibiotics af Haldar, K, Bafadhel, M, Lau, K, Berg, A, Kwambana, B, Kebadze, T, Ramsheh, MY, Barker, B, Haldar, P, Johnston, S, Ketley, JM, Brightling, CE, Barer, MR

Lung microbiome dynamics in COPD exacerbations af Wang, Z, Bafadhel, M, Haldar, K, Spivak, A, Mayhew, D, Miller, BE, Tal-Singer, R, Johnston, SL, Ramsheh, MY, Barer, MR, Brightling, CE, Brown, JR

Sputum Streptococcus pneumoniae is reduced in COPD following treatment with benralizumab af George L, Wright A, Mistry V, Sutcliffe A, Chachi L, Haldar K, Ramsheh MY, Richardson M, van der Merwe R, Martin U, Newbold P, Brightling CE

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Airway proteomics reveals broad residual anti-inflammatory effects of prednisolone in mepolizumab-treated asthma af Howell, I, Yang, F, Brown, V, Cane, J, Marchi, E, Azim, A, Busby, J, McDowell, PJ, Diver, SE, Borg, C, Heaney, LG, Pavord, ID, Brightling, CE, Chaudhuri, R, Hinks, TSC

Symptom persistence despite improvement in cardiopulmonary health -- Insights from longitudinal CMR, CPET and lung function testing post-COVID-19 af Cassar, MP, Tunnicliffe, EM, Petousi, N, Lewandowski, AJ, Xie, C, Mahmod, M, Samat, AHA, Evans, RA, Brightling, CE, Ho, L-P, Piechnik, SK, Talbot, NP, Holdsworth, D, Ferreira, VM, Neubauer, S, Raman, B

DP2 antagonism reduces airway smooth muscle mass in asthma by decreasing eosinophilia and myofibroblast recruitment af Saunders, R, Kaul, H, Berair, R, Gonem, S, Singapuri, A, Sutcliffe, AJ, Chachi, L, Biddle, MS, Kaur, D, Bourne, M, Pavord, ID, Wardlaw, AJ, Siddiqui, SH, Kay, RA, Brook, BS, Smallwood, RH, Brightling, CE