A Portable, Negative-Pressure Actuated, Dynamically Tunable Microfluidic Droplet Generator by Martin Trossbach, Marta de Lucas Sanz, Brinton Seashore-Ludlow, Haakan N. Joensson

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Evaluating feature extraction in ovarian cancer cell line co-cultures using deep neural networks by Osheen Sharma, Greta Gudoityte, Rezan Minozada, Olli P. Kallioniemi, Riku Turkki, Lassi Paavolainen, Brinton Seashore-Ludlow

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Functional-proteomics-based investigation of the cellular response to farnesyltransferase inhibition in lung cancer by Yanbo Pan, Olena Berkovska, Soumitra Marathe, Georgios Mermelekas, Greta Gudoityte, Amare D. Wolide, Taner Arslan, Brinton Seashore-Ludlow, Janne Lehtiö, Lukas M. Orre

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High‐content screening of drug combinations of an mPGES‐1 inhibitor in multicellular tumor spheroids leads to mechanistic insights into neuroblastoma chemoresistance by Ahlem Zaghmi, Erdem Aybay, Long Jiang, Mingmei Shang, Julia Steinmetz‐Späh, Fredrik Wermeling, Per Kogner, Marina Korotkova, Päivi Östling, Per‐Johan Jakobsson, Brinton Seashore‐Ludlow, Karin Larsson

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Targeting autophagy as a therapeutic strategy in pediatric acute lymphoblastic leukemia by Henri Colyn Bwanika, Isabelle Rose Leo, Nona Struyf, Asimina Talanti, Luay Aswad, Aishwarya Konnur, Ann-Charlotte Björklund, Mats Heyman, Georgios Rassidakis, Tom Erkers, Brinton Seashore-Ludlow, Rozbeh Jafari, Katja Pokrovskaja Tamm

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The drug efficacy testing in 3D cultures platform identifies effective drugs for ovarian cancer patients by Emma Åkerlund, Greta Gudoityte, Elisabeth Moussaud-Lamodière, Olina Lind, Henri Colyn Bwanika, Kaisa Lehti, Sahar Salehi, Joseph Carlson, Emelie Wallin, Josefin Fernebro, Päivi Östling, Olli Kallioniemi, Ulrika Joneborg, Brinton Seashore-Ludlow

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Multiomics characterization implicates PTK7 in ovarian cancer EMT and cell plasticity and offers strategies for therapeutic intervention by Juuli Raivola, Alice Dini, Hanna Karvonen, Emilia Piki, Kari Salokas, Wilhelmiina Niininen, Laura Kaleva, Kaiyang Zhang, Mariliina Arjama, Greta Gudoityte, Brinton Seashore-Ludlow, Markku Varjosalo, Olli Kallioniemi, Sampsa Hautaniemi, Astrid Murumägi, Daniela Ungureanu

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A phenotypic screening approach to target p60AmotL2-expressing invasive cancer cells by Pedro Fonseca, Weiyingqi Cui, Nona Struyf, Le Tong, Ayushi Chaurasiya, Felipe Casagrande, Honglei Zhao, Dinura Fernando, Xinsong Chen, Nicholas P. Tobin, Brinton Seashore-Ludlow, Andreas Lundqvist, Johan Hartman, Anita Göndör, Päivi Östling, Lars Holmgren

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Targeting CDK2 overcomes melanoma resistance against BRAF and Hsp90 inhibitors by Alireza Azimi, Stefano Caramuta, Brinton Seashore‐Ludlow, Johan Boström, Jonathan L Robinson, Fredrik Edfors, Rainer Tuominen, Kristel Kemper, Oscar Krijgsman, Daniel S Peeper, Jens Nielsen, Johan Hansson, Suzanne Egyhazi Brage, Mikael Altun, Mathias Uhlen, Gianluca Maddalo

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Delineating functional and molecular impact of ex vivo sample handling in precision medicine by Nona Struyf, Albin Österroos, Mattias Vesterlund, Cornelia Arnroth, Tojo James, Stephanie Sunandar, Georgios Mermelekas, Anna Bohlin, Kerstin Hamberg Levedahl, Sofia Bengtzén, Rozbeh Jafari, Lukas M. Orre, Janne Lehtiö, Sören Lehmann, Päivi Östling, Olli Kallioniemi, Brinton Seashore-Ludlow, Tom Erkers

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SETD8 inhibition targets cancer cells with increased rates of ribosome biogenesis by Matilde Murga, Gema Lopez-Pernas, Robert Soliva, Elena Fueyo-Marcos, Corina Amor, Ignacio Faustino, Marina Serna, Alicia G. Serrano, Lucía Díaz, Sonia Martínez, Carmen Blanco-Aparicio, Marta Elena Antón, Brinton Seashore-Ludlow, Joaquín Pastor, Rozbeh Jafari, Miguel Lafarga, Oscar Llorca, Modesto Orozco, Oscar Fernández-Capetillo

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Chemogenomic Screening in a Patient‐Derived 3D Fatty Liver Disease Model Reveals the CHRM1‐TRPM8 Axis as a Novel Module for Targeted Intervention by Sonia Youhanna, Aurino M. Kemas, Shane C. Wright, Yi Zhong, Britta Klumpp, Kathrin Klein, Aikaterini Motso, Maurice Michel, Nicole Ziegler, Mingmei Shang, Pierre Sabatier, Aimo Kannt, Hongda Sheng, Nuria Oliva‐Vilarnau, Florian A. Büttner, Brinton Seashore‐Ludlow, Jonas Schreiner, Maike Windbergs, Martin Cornillet, Niklas K. Björkström, Andreas J. Hülsmeier, Thorsten Hornemann, Jesper V. Olsen, Yi Wang, Roberto Gramignoli, Michael Sundström, Volker M. Lauschke

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