Science in focus: Bioinformatics part 1 – Lost in translation gan O'Cathail, SM, Buffa, FM

Robustness and reproducibility for AI learning in biomedical sciences: RENOIR gan Barberis, A, Aerts, HJWL, Buffa, FM

Endogenous miRNA sponges mediate the generation of oscillatory dynamics for a non-coding RNA network gan Dhawan, A, Harris, AL, Buffa, FM, Scott, JG

The MITF regulatory network in melanoma gan Chauhan, JS, Hölzel, M, Lambert, J-P, Buffa, FM, Goding, CR

MITF controls the TCA cycle to modulate the melanoma hypoxia response gan Louphrasitthiphol, P, Ledaki, I, Chauhan, J, Falletta, P, Siddaway, R, Buffa, FM, Mole, DR, Soga, T, Goding, CR

Role of gene signatures combined with pathology in classification of oropharynx head and neck cancer gan Dhawan, A, Scott, J, Sundaresan, P, Veness, M, Porceddu, S, Hau, E, Harris, AL, Buffa, FM, Gee, HE

Are signatures of radiosensitivity ready for routine clinical use? A pragmatic comparison of clinical, pathological, and gene signature predictors of outcome in oropharynx head and... gan Dhawan, A, Scott, JG, Sundaresan, P, Veness, M, Porceddu, S, Hau, E, Ahern, V, Harris, AL, Buffa, FM, Gee, HE

Disease-associated KBTBD4 mutations in medulloblastoma elicit neomorphic ubiquitylation activity to promote CoREST degradation gan Chen, Z, Ioris, RM, Richardson, S, Van Ess, AN, Vendrell, I, Kessler, BM, Buffa, FM, Busino, L, Clifford, SC, Bullock, AN, D'Angiolella, V

Molecular analysis of archival diagnostic prostate cancer biopsies identifies genomic similarities in cases with progression post-radiotherapy, and those with de novo metastatic di... gan Charlton, PV, O'Reilly, D, Philippou, Y, Rao, SR, Lamb, ADG, Mills, IG, Higgins, GS, Hamdy, FC, Verrill, C, Buffa, FM, Bryant, RJ

Molecular analysis of archival diagnostic prostate cancer biopsies identifies genomic similarities in cases with progression post-radiotherapy, and those with de novo metastatic di... gan Charlton, P, O’Reilly, D, Philippou, Y, Rao, SR, Lamb, AD, Mills, IG, Higgins, G, Hamdy, FC, Verrill, C, Buffa, FM, Bryant, RJ

New role of fat-free mass in cancer risk linked with genetic predisposition gan Harris, BHL, Di Giovannantonio, M, Zhang, P, Harris, DA, Lord, SR, Allen, NE, Maughan, TS, Bryant, RJ, Harris, AL, Bond, GL, Buffa, FM

Cyclin F–EXO1 axis controls cell cycle–dependent execution of double-strand break repair gan Yang, H, Fouad, S, Smith, P, Bae, EY, Ji, Y, Lan, X, Van Ess, A, Buffa, FM, Fischer, R, Vendrell, I, Kessler, BM, D’Angiolella, V

Disruption of hypoxia-inducible fatty acid binding protein 7 induces beige fat-like differentiation and thermogenesis in breast cancer cells gan Kawashima, M, Bensaad, K, Zois, CE, Barberis, A, Bridges, E, Wigfield, S, Lagerholm, C, Dmitriev, RI, Tokiwa, M, Toi, M, Papkovsky, DB, Buffa, FM, Harris, AL

Heritable genetic variants in key cancer genes link cancer risk with anthropometric traits gan Di Giovannantonio, M, Harris, BHL, Zhang, P, Kitchen-Smith, I, Xiong, L, Sahgal, N, Stracquadanio, G, Wallace, M, Blagden, S, Lord, S, Harris, D, Harris, AHL, Buffa, FM, Bond, GL

Liver glycogen phosphorylase is upregulated in glioblastoma and provides a metabolic vulnerability to high dose radiation gan Zois, CE, Hendriks, AM, Haider, S, Pires, E, Bridges, E, Kalamida, D, Voukantsis, D, Lagerholm, BC, Fehrmann, RSN, den Dunnen, WFA, Tarasov, AI, Baba, O, Morris, J, Buffa, FM, McCullagh, JSO, Jalving, M, Harris, AL

miR-139-5p modulates radiotherapy resistance in breast cancer by repressing multiple gene networks of DNA repair and ROS defense. gan Pajic, M, Froio, D, Daly, S, Doculara, L, Millar, E, Graham, PH, Drury, A, Steinmann, A, de Bock, CE, Boulghourjian, A, Zaratzian, A, Carroll, S, Toohey, J, O'Toole, SA, Harris, AL, Buffa, FM, Gee, HE, Hollway, GE, Molloy, TJ

Hypoxia promotes stem cell phenotypes and poor prognosis through epigenetic regulation of DICER gan Van Den Beucken, T, Koch, E, Chu, K, Rupaimoole, R, Prickaerts, P, Adriaens, M, Voncken, JW, Harris, AL, Buffa, FM, Haider, S, Starmans, MHW, Yao, CQ, Ivan, M, Ivan, C, Pecot, CV, Boutros, PC, Sood, AK, Koritzinsky, M, Wouters, BG

Adaptation to HIF1α deletion in hypoxic cancer cells by upregulation of GLUT14 and creatine metabolism gan Valli, A, Morotti, M, Zois, CE, Albers, PK, Soga, T, Feldinger, K, Fischer, R, Frejno, M, McIntyre, A, Bridges, E, Haider, S, Buffa, FM, Baban, D, Rodriguez, M, Yanes, O, Whittington, HJ, Lake, HA, Zervou, S, Lygate, CA, Kessler, BM, Harris, AL

Clinical whole-genome sequencing from routine formalin-fixed, paraffin-embedded specimens: pilot study for the 100,000 Genomes Project. gan Robbe, P, Popitsch, N, Knight, SJL, Antoniou, P, Becq, J, He, M, Kanapin, A, Samsonova, A, Vavoulis, DV, Ross, MT, Kingsbury, Z, Cabes, M, Ramos, SDC, Page, S, Dreau, H, Ridout, K, Jones, LJ, Tuff-Lacey, A, Henderson, S, Mason, J, Buffa, FM, Verrill, CL, Maldonado-Perez, D, Roxanis, I, Collantes, E, Browning, L, Dhar, S, Damato, SP, Davies, S, Caulfield, M, Bentley, DR, Taylor, JC, Turnbull, C, Schuh, A