Science in focus: Bioinformatics part 1 – Lost in translation ανά O'Cathail, SM, Buffa, FM

Robustness and reproducibility for AI learning in biomedical sciences: RENOIR ανά Barberis, A, Aerts, HJWL, Buffa, FM

Endogenous miRNA sponges mediate the generation of oscillatory dynamics for a non-coding RNA network ανά Dhawan, A, Harris, AL, Buffa, FM, Scott, JG

The MITF regulatory network in melanoma ανά Chauhan, JS, Hölzel, M, Lambert, J-P, Buffa, FM, Goding, CR

MITF controls the TCA cycle to modulate the melanoma hypoxia response ανά Louphrasitthiphol, P, Ledaki, I, Chauhan, J, Falletta, P, Siddaway, R, Buffa, FM, Mole, DR, Soga, T, Goding, CR

Role of gene signatures combined with pathology in classification of oropharynx head and neck cancer ανά Dhawan, A, Scott, J, Sundaresan, P, Veness, M, Porceddu, S, Hau, E, Harris, AL, Buffa, FM, Gee, HE

Are signatures of radiosensitivity ready for routine clinical use? A pragmatic comparison of clinical, pathological, and gene signature predictors of outcome in oropharynx head and... ανά Dhawan, A, Scott, JG, Sundaresan, P, Veness, M, Porceddu, S, Hau, E, Ahern, V, Harris, AL, Buffa, FM, Gee, HE

Disease-associated KBTBD4 mutations in medulloblastoma elicit neomorphic ubiquitylation activity to promote CoREST degradation ανά Chen, Z, Ioris, RM, Richardson, S, Van Ess, AN, Vendrell, I, Kessler, BM, Buffa, FM, Busino, L, Clifford, SC, Bullock, AN, D'Angiolella, V

Molecular analysis of archival diagnostic prostate cancer biopsies identifies genomic similarities in cases with progression post-radiotherapy, and those with de novo metastatic di... ανά Charlton, PV, O'Reilly, D, Philippou, Y, Rao, SR, Lamb, ADG, Mills, IG, Higgins, GS, Hamdy, FC, Verrill, C, Buffa, FM, Bryant, RJ

Molecular analysis of archival diagnostic prostate cancer biopsies identifies genomic similarities in cases with progression post-radiotherapy, and those with de novo metastatic di... ανά Charlton, P, O’Reilly, D, Philippou, Y, Rao, SR, Lamb, AD, Mills, IG, Higgins, G, Hamdy, FC, Verrill, C, Buffa, FM, Bryant, RJ

New role of fat-free mass in cancer risk linked with genetic predisposition ανά Harris, BHL, Di Giovannantonio, M, Zhang, P, Harris, DA, Lord, SR, Allen, NE, Maughan, TS, Bryant, RJ, Harris, AL, Bond, GL, Buffa, FM

Cyclin F–EXO1 axis controls cell cycle–dependent execution of double-strand break repair ανά Yang, H, Fouad, S, Smith, P, Bae, EY, Ji, Y, Lan, X, Van Ess, A, Buffa, FM, Fischer, R, Vendrell, I, Kessler, BM, D’Angiolella, V

Disruption of hypoxia-inducible fatty acid binding protein 7 induces beige fat-like differentiation and thermogenesis in breast cancer cells ανά Kawashima, M, Bensaad, K, Zois, CE, Barberis, A, Bridges, E, Wigfield, S, Lagerholm, C, Dmitriev, RI, Tokiwa, M, Toi, M, Papkovsky, DB, Buffa, FM, Harris, AL

Heritable genetic variants in key cancer genes link cancer risk with anthropometric traits ανά Di Giovannantonio, M, Harris, BHL, Zhang, P, Kitchen-Smith, I, Xiong, L, Sahgal, N, Stracquadanio, G, Wallace, M, Blagden, S, Lord, S, Harris, D, Harris, AHL, Buffa, FM, Bond, GL

Liver glycogen phosphorylase is upregulated in glioblastoma and provides a metabolic vulnerability to high dose radiation ανά Zois, CE, Hendriks, AM, Haider, S, Pires, E, Bridges, E, Kalamida, D, Voukantsis, D, Lagerholm, BC, Fehrmann, RSN, den Dunnen, WFA, Tarasov, AI, Baba, O, Morris, J, Buffa, FM, McCullagh, JSO, Jalving, M, Harris, AL

miR-139-5p modulates radiotherapy resistance in breast cancer by repressing multiple gene networks of DNA repair and ROS defense. ανά Pajic, M, Froio, D, Daly, S, Doculara, L, Millar, E, Graham, PH, Drury, A, Steinmann, A, de Bock, CE, Boulghourjian, A, Zaratzian, A, Carroll, S, Toohey, J, O'Toole, SA, Harris, AL, Buffa, FM, Gee, HE, Hollway, GE, Molloy, TJ

Hypoxia promotes stem cell phenotypes and poor prognosis through epigenetic regulation of DICER ανά Van Den Beucken, T, Koch, E, Chu, K, Rupaimoole, R, Prickaerts, P, Adriaens, M, Voncken, JW, Harris, AL, Buffa, FM, Haider, S, Starmans, MHW, Yao, CQ, Ivan, M, Ivan, C, Pecot, CV, Boutros, PC, Sood, AK, Koritzinsky, M, Wouters, BG

Adaptation to HIF1α deletion in hypoxic cancer cells by upregulation of GLUT14 and creatine metabolism ανά Valli, A, Morotti, M, Zois, CE, Albers, PK, Soga, T, Feldinger, K, Fischer, R, Frejno, M, McIntyre, A, Bridges, E, Haider, S, Buffa, FM, Baban, D, Rodriguez, M, Yanes, O, Whittington, HJ, Lake, HA, Zervou, S, Lygate, CA, Kessler, BM, Harris, AL

Clinical whole-genome sequencing from routine formalin-fixed, paraffin-embedded specimens: pilot study for the 100,000 Genomes Project. ανά Robbe, P, Popitsch, N, Knight, SJL, Antoniou, P, Becq, J, He, M, Kanapin, A, Samsonova, A, Vavoulis, DV, Ross, MT, Kingsbury, Z, Cabes, M, Ramos, SDC, Page, S, Dreau, H, Ridout, K, Jones, LJ, Tuff-Lacey, A, Henderson, S, Mason, J, Buffa, FM, Verrill, CL, Maldonado-Perez, D, Roxanis, I, Collantes, E, Browning, L, Dhar, S, Damato, SP, Davies, S, Caulfield, M, Bentley, DR, Taylor, JC, Turnbull, C, Schuh, A