Resistance Mutations to BTK Inhibitors Originate From the NF-κB but Not From the PI3K-RAS-MAPK Arm of the B Cell Receptor Signaling Pathway 由 C. I. Edvard Smith, Jan A. Burger

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COVID-19 in a patient with Good's syndrome and in 13 patients with common variable immunodeficiency 由 Hannes Lindahl, C I Edvard Smith, Peter Bergman

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Estimating the number of diseases – the concept of rare, ultra-rare, and hyper-rare 由 C. I. Edvard Smith, Peter Bergman, Daniel W. Hagey

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Editorial: New Insights on Bruton’s Tyrosine Kinase Inhibitors 由 C. I. Edvard Smith, Jennifer R. Brown, Rula Zain, Rula Zain

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Oligonucleotide–Palladacycle Conjugates as Splice-Correcting Agents 由 Madhuri Hande, Osama Saher, Karin E. Lundin, C. I. Edvard Smith, Rula Zain, Tuomas Lönnberg

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Exposure to Therapeutic BTK Inhibitors Induces Phenocopying of Btk29A Mutants in the Fruit Fly Drosophila melanogaster 由 Noriko Hamada-Kawaguchi, Beston F. Nore, Rula Zain, Ylva Engström, C. I. Edvard Smith, Daisuke Yamamoto

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Comparative Analysis of BTK Inhibitors and Mechanisms Underlying Adverse Effects 由 H. Yesid Estupiñán, H. Yesid Estupiñán, Anna Berglöf, Rula Zain, Rula Zain, C. I. Edvard Smith

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Differential evolutionary wiring of the tyrosine kinase Btk. 由 Hossain M Nawaz, Per Kylsten, Noriko Hamada, Daisuke Yamamoto, C I Edvard Smith, Jessica M Lindvall

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Diagnostics of primary immunodeficiency diseases: a sequencing capture approach. 由 Lotte N Moens, Elin Falk-Sörqvist, A Charlotta Asplund, Ewa Bernatowska, C I Edvard Smith, Mats Nilsson

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Oligonucleotide Binding to Non-B-DNA in MYC 由 Tea Umek, Karin Sollander, Helen Bergquist, Jesper Wengel, Karin E. Lundin, C.I. Edvard Smith, Rula Zain

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mRNA and microRNA transcriptomics analyses in a murine model of dystrophin loss and therapeutic restoration 由 Thomas C. Roberts, K. Emelie M. Blomberg, C.I. Edvard Smith, Samir EL Andaloussi, Matthew J.A. Wood

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The ability of locked nucleic acid oligonucleotides to pre-structure the double helix: A molecular simulation and binding study. 由 You Xu, Olof Gissberg, Y Vladimir Pabon-Martinez, Jesper Wengel, Karin E Lundin, C I Edvard Smith, Rula Zain, Lennart Nilsson, Alessandra Villa

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Clinical measurement of cellular DNA damage hypersensitivity in patients with DNA repair defects 由 Ola Hammarsten, Anna Lyytikäinen, Sofia Thunström, Torben Ek, Anders Fasth, Olov Ekwall, Sara Cajander, Emilie Wahren Borgström, C. I. Edvard Smith, Pegah Johansson

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Predisposition to childhood acute lymphoblastic leukemia caused by a constitutional translocation disrupting ETV6 由 Tekla Järviaho, Benedicte Bang, Vasilios Zachariadis, Fulya Taylan, Jukka Moilanen, Merja Möttönen, C.I. Edvard Smith, Arja Harila-Saari, Riitta Niinimäki, Ann Nordgren

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ANKRD54 preferentially selects Bruton's Tyrosine Kinase (BTK) from a Human Src-Homology 3 (SH3) domain library. 由 Manuela O Gustafsson, Dara K Mohammad, Erkko Ylösmäki, Hyunseok Choi, Subhash Shrestha, Qing Wang, Beston F Nore, Kalle Saksela, C I Edvard Smith

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Differential regulatory effects of the N-terminal region in SYK-fusion kinases reveal unique activation-inducible nuclear translocation of ITK-SYK 由 Abdulrahman Hamasy, Alamdar Hussain, Dara K. Mohammad, Qing Wang, Manuela Gustafsson Sfetcovici, Beston F. Nore, Abdalla J. Mohamed, Rula Zain, C. I. Edvard Smith

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Eleven percent intact PGM3 in a severely immunodeficient patient with a novel splice-site mutation, a case report 由 Karin E. Lundin, Qing Wang, Abdulrahman Hamasy, Per Marits, Mehmet Uzunel, Valtteri Wirta, Ann-Charlotte Wikström, Anders Fasth, Olov Ekwall, C.I. Edvard Smith

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Disruption of Higher Order DNA Structures in Friedreich's Ataxia (GAA)n Repeats by PNA or LNA Targeting. 由 Helen Bergquist, Cristina S J Rocha, Rubén Álvarez-Asencio, Chi-Hung Nguyen, Mark W Rutland, C I Edvard Smith, Liam Good, Peter E Nielsen, Rula Zain

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Ibrutinib Has Time-dependent On- and Off-target Effects on Plasma Biomarkers and Immune Cells in Chronic Lymphocytic Leukemia 由 Tom A. Mulder, Lucía Peña-Pérez, Anna Berglöf, Stephan Meinke, H. Yesid Estupiñán, Kia Heimersson, Rula Zain, Robert Månsson, C. I. Edvard Smith, Marzia Palma

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Lipophilic Peptide Dendrimers for Delivery of Splice-Switching Oligonucleotides 由 Haneen Daralnakhla, Osama Saher, Susanna Zamolo, Safa Bazaz, Jeremy P. Bost, Marc Heitz, Karin E. Lundin, Samir EL Andaloussi, Tamis Darbre, Jean-Louis Reymond, Rula Zain, C. I. Edvard Smith

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