Cytokines in CAR T Cell–Associated Neurotoxicity by Juliane Gust, Juliane Gust, Rafael Ponce, W. Conrad Liles, Gwenn A. Garden, Cameron J. Turtle, Cameron J. Turtle

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PD‐L1+ macrophage and tumor cell abundance and proximity to T cells in the pretreatment large B‐cell lymphoma microenvironment impact CD19 CAR‐T cell immunotherapy efficacy by Alexandre V. Hirayama, Jocelyn H. Wright, Kimberly S. Smythe, Salvatore Fiorenza, Akira N. Shaw, Jordan Gauthier, David G. Maloney, Kikkeri N. Naresh, Cecilia C. S. Yeung, Cameron J. Turtle

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Targeting the membrane-proximal C2-set domain of CD33 for improved CAR T cell therapy by Salvatore Fiorenza, Sheryl Y.T. Lim, George S. Laszlo, Erik L. Kimble, Tinh-Doan Phi, Margaret C. Lunn-Halbert, Delaney R. Kirchmeier, Jenny Huo, Hans-Peter Kiem, Cameron J. Turtle, Roland B. Walter

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Stealth transgenes enable CAR-T cells to evade host immune responses by David Millar, Rebecca Larson, Marcela V Maus, Amanda A Bouffard, Matthew J Frigault, Stefanie R Bailey, Mark B Leick, Michael C Kann, Cameron J Turtle, Trisha Berger, Kathleen Gallagher, Korneel Grauwet, Harrison Silva

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Durable preservation of antiviral antibodies after CD19-directed chimeric antigen receptor T-cell immunotherapy by Joshua A. Hill, Elizabeth M. Krantz, Kevin A. Hay, Sayan Dasgupta, Terry Stevens-Ayers, Rachel A. Bender Ignacio, Merav Bar, Joyce Maalouf, Sindhu Cherian, Xueyan Chen, Greg Pepper, Stanley R. Riddell, David G. Maloney, Michael J. Boeckh, Cameron J. Turtle

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Safety of allogeneic hematopoietic cell transplant in adults after CD19-targeted CAR T-cell therapy by Mazyar Shadman, Jordan Gauthier, Kevin A. Hay, Jenna M. Voutsinas, Filippo Milano, Ang Li, Alexandre V. Hirayama, Mohamed L. Sorror, Sindhu Cherian, Xueyan Chen, Ryan D. Cassaday, Brian G. Till, Ajay K. Gopal, Brenda M. Sandmaier, David G. Maloney, Cameron J. Turtle

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Clonal kinetics and single-cell transcriptional profiling of CAR-T cells in patients undergoing CD19 CAR-T immunotherapy by Alyssa Sheih, Valentin Voillet, Laïla-Aïcha Hanafi, Hannah A. DeBerg, Masanao Yajima, Reed Hawkins, Vivian Gersuk, Stanley R. Riddell, David G. Maloney, Martin E. Wohlfahrt, Dnyanada Pande, Mark R. Enstrom, Hans-Peter Kiem, Jennifer E. Adair, Raphaël Gottardo, Peter S. Linsley, Cameron J. Turtle

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Real-world outcomes with tisagenlecleucel in aggressive B-cell lymphoma: subgroup analyses from the CIBMTR registry by Frederick L Locke, Grant Schofield, Marcelo Pasquini, Matthew J Frigault, Cameron J Turtle, Stephen Lim, Brian Hill, Samantha Jaglowski, Caron A Jacobson, Gunjan Shah, Daniel J Landsburg, Michael Heim, Stephen Ronan Foley, Ron Ram, Peter A Riedell, Leslie L Popplewell, Ranjan Tiwari, Marta Majdan, Aisha Masood

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Antibodies against vaccine-preventable infections after CAR-T cell therapy for B cell malignancies by Carla S. Walti, Elizabeth M. Krantz, Joyce Maalouf, Jim Boonyaratanakornkit, Jacob Keane-Candib, Laurel Joncas-Schronce, Terry Stevens-Ayers, Sayan Dasgupta, Justin J. Taylor, Alexandre V. Hirayama, Merav Bar, Rebecca A. Gardner, Andrew J. Cowan, Damian J. Green, Michael J. Boeckh, David G. Maloney, Cameron J. Turtle, Joshua A. Hill

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Humoral immunogenicity of the seasonal influenza vaccine before and after CAR-T-cell therapy: a prospective observational study by Helen Y Chu, Caitlin R Wolf, Rebecca A Gardner, Cameron J Turtle, Joshua A Hill, Carla S Walti, Andrea N Loes, Kiel Shuey, Elizabeth M Krantz, Jim Boonyaratanakornkit, Jacob Keane-Candib, Tillie Loeffelholz, Justin J Taylor, Damian J Green, Andrew J Cowan, David G Maloney, Steven A Pergam, Jesse D Bloom

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Society for Immunotherapy of Cancer (SITC) clinical practice guideline on immune effector cell-related adverse events by Frederick L Locke, Stephan A Grupp, Elizabeth J Shpall, Sattva S Neelapu, Michael R Bishop, Marcela V Maus, Jorg Dietrich, Daniel W Lee, Matthew J Frigault, Terry J Fry, Sara Alexander, Jennifer N Brudno, Colleen Callahan, Marco L Davila, Claudia Diamonte, Julie C Fitzgerald, Jennifer L Holter-Chakrabarty, Krishna V Komanduri, Shannon L Maude, Philip L McCarthy, Elena Mead, Tomas G Neilan, Bianca D Santomasso, David T Teachey, Cameron J Turtle, Tom Whitehead

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Development and validation of predictive models of early immune effector cell–associated hematotoxicity by Emily C. Liang, Jennifer J. Huang, Andrew J. Portuguese, Valentín Ortiz-Maldonado, Aya Albittar, Natalie Wuliji, Ryan Basom, Yein Jeon, Qian Wu, Aiko Torkelson, Delaney Kirchmeier, Abigail Chutnik, Barbara Pender, Mohamed Sorror, Joshua A. Hill, Noam E. Kopmar, Rahul Banerjee, Andrew J. Cowan, Damian Green, Ajay K. Gopal, Christina Poh, Mazyar Shadman, Alexandre V. Hirayama, Brian G. Till, Erik L. Kimble, Lorenzo Iovino, Aude G. Chapuis, Folashade Otegbeye, Ryan D. Cassaday, Filippo Milano, Cameron J. Turtle, David G. Maloney, Jordan Gauthier

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Evidence generation and reproducibility in cell and gene therapy research: A call to action by Mohamed Abou-el-Enein, Aris Angelis, Frederick R. Appelbaum, Nancy C. Andrews, Susan E. Bates, Arlene S. Bierman, Malcolm K. Brenner, Marina Cavazzana, Michael A. Caligiuri, Hans Clevers, Emer Cooke, George Q. Daley, Victor J. Dzau, Lee M. Ellis, Harvey V. Fineberg, Lawrence S.B. Goldstein, Stephen Gottschalk, Margaret A. Hamburg, Donald E. Ingber, Donald B. Kohn, Adrian R. Krainer, Marcela V. Maus, Peter Marks, Christine L. Mummery, Roderic I. Pettigrew, Joni L. Rutter, Sarah A. Teichmann, Andre Terzic, Fyodor D. Urnov, David A. Williams, Jedd D. Wolchok, Mark Lawler, Cameron J. Turtle, Gerhard Bauer, John P.A. Ioannidis

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