What’s New in the Classification, Diagnosis and Therapy of Myeloid Leukemias by Marco Pizzi, Carmela Gurrieri, Attilio Orazi

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Severe haemorrhagic diathesis due to acquired hypofibrinogenemia in a patient with early T-cell precursor acute lymphoblastic leukaemia/lymphoma: a case report by Luca Spiezia, Marcello Riva, Carmela Gurrieri, Elena Campello, Paolo Simioni

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Intramural hematoma of the esophagus in a woman with chronic renal failure and prophylactic heparin therapy by Francesco Serafini, Giuseppe Fantin, Andrea Zancanaro, Carmela Gurrieri, Luca Bonanni, Gabriele Bittolo Bon

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Limbic Encephalitis with HU-Antibodies in T-cell Anaplastic Lymphoma. A Case Report by Carmela Gurrieri, Andrea Visentin, Cinzia Bussè, Francesco Piazza, Renzo Manara, Livio Trentin, Chiara Briani

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A Case of Hemophagocytic Lymphohistiocytosis Triggered by Disseminated Tuberculosis and Hairy Cell Leukaemia after SARS-CoV2 Infection by Alessandro Cellini, Andrea Visentin, Massimiliano Arangio Febbo, Susanna Vedovato, Serena Marinello, Ivo Tiberio, Livio Trentin, Carmela Gurrieri

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Efficacy and safety of venetoclax plus hypomethylating agents in relapsed/refractory acute myeloid leukemia: a multicenter real-life experience by Francesco Angotzi, Federica Lessi, Matteo Leoncin, Carla Filì, Mauro Endri, Albana Lico, Andrea Visentin, Stefano Pravato, Anna Candoni, Livio Trentin, Carmela Gurrieri

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PB1858: PROGNOSIS AND TREATMENT OF FLT3 MUTATED MYELOID SARCOMA IN THE ERA OF FLT3 INHIBITORS: RETROSPECTIVE EVALUATION IN 5 ITALIAN CENTERS. by Federica Lessi, Erika Borlenghi, Chiara Sartor, Calogero Vetro, Ernesta Audisio, Federico Vincenzo, Andrea Visentin, Federica Loscocco, Carmela Gurrieri, Livio Trentin, Felicetto Ferrara

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Protein Kinase CK2 represents a new target to boost Ibrutinib and Venetoclax induced cytotoxicity in mantle cell lymphoma by Sabrina Manni, Sabrina Manni, Maria Pesavento, Maria Pesavento, Zaira Spinello, Zaira Spinello, Lara Saggin, Lara Saggin, Arash Arjomand, Arash Arjomand, Anna Fregnani, Anna Fregnani, Laura Quotti Tubi, Laura Quotti Tubi, Greta Scapinello, Greta Scapinello, Carmela Gurrieri, Carmela Gurrieri, Gianpietro Semenzato, Gianpietro Semenzato, Livio Trentin, Livio Trentin, Francesco Piazza, Francesco Piazza

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Protein Kinase CK1α Sustains B-Cell Receptor Signaling in Mantle Cell Lymphoma by Sabrina Manni, Sabrina Manni, Anna Fregnani, Anna Fregnani, Laura Quotti Tubi, Laura Quotti Tubi, Zaira Spinello, Zaira Spinello, Marco Carraro, Marco Carraro, Greta Scapinello, Greta Scapinello, Andrea Visentin, Andrea Visentin, Gregorio Barilà, Gregorio Barilà, Marco Pizzi, Angelo Paolo Dei Tos, Fabrizio Vianello, Renato Zambello, Renato Zambello, Carmela Gurrieri, Carmela Gurrieri, Gianpietro Semenzato, Gianpietro Semenzato, Livio Trentin, Livio Trentin, Francesco Piazza, Francesco Piazza

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GSK-3 Inhibition Modulates Metalloproteases in a Model of Lung Inflammation and Fibrosis by Francesco Cinetto, Jessica Ceccato, Ilaria Caputo, Daniela Cangiano, Barbara Montini, Francesca Lunardi, Maria Piazza, Carlo Agostini, Fiorella Calabrese, Gianpietro Semenzato, Marcello Rattazzi, Carmela Gurrieri, Riccardo Scarpa, Carla Felice, Fabrizio Vianello

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P1111: WALDENSTRÖM MACROGLOBULINEMIA IN THE VERY ELDERLY (≥75-YEAR-OLD): DESCRIPTION OF CLINICAL FEATURES AND SURVIVAL OUTCOMES IN A CASE SERIES FROM AN ITALIAN ACADEMIC CENTER by Nicolò Danesin, Mariella Lo Schirico, Greta Scapinello, Marco Carraro, Laura Bonaldi, Roberta Bertorelle, Andrea Visentin, Tamara Berno, Antonio Branca, Marcello Riva, Renato Zambello, Fabrizio Vianello, Carmela Gurrieri, Livio Trentin, Francesco Piazza

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Sequential allogeneic transplantation and ruxolitinib maintenance for a synchronous PCM1‐JAK2 positive myeloid sarcoma and acute B‐lymphoblastic leukemia by Giuliana Rizzuto, Matteo Leoncin, Silvia Imbergamo, Daniela Taurino, Maria Caterina Mico, Manuela Tosi, Anna Michelato, Ksenija Buklijas, Orietta Spinelli, Federico Lussana, Federica Lessi, Marco Pizzi, Laura Bonaldi, Gianni Binotto, Alessandro Rambaldi, Carmela Gurrieri

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CK1α/RUNX2 Axis in the Bone Marrow Microenvironment: A Novel Therapeutic Target in Multiple Myeloma by Anna Fregnani, Lara Saggin, Ketty Gianesin, Laura Quotti Tubi, Marco Carraro, Gregorio Barilà, Greta Scapinello, Giorgia Bonetto, Maria Pesavento, Tamara Berno, Antonio Branca, Carmela Gurrieri, Renato Zambello, Gianpietro Semenzato, Livio Trentin, Sabrina Manni, Francesco Piazza

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Protein kinase CK2 inhibition down modulates the NF-κB and STAT3 survival pathways, enhances the cellular proteotoxic stress and synergistically boosts the cytotoxic effect of bort... by Sabrina Manni, Alessandra Brancalion, Elisa Mandato, Laura Quotti Tubi, Anna Colpo, Marco Pizzi, Rocco Cappellesso, Fortunato Zaffino, Speranza Antonia Di Maggio, Anna Cabrelle, Filippo Marino, Renato Zambello, Livio Trentin, Fausto Adami, Carmela Gurrieri, Gianpietro Semenzato, Francesco Piazza

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Waldenström Macroglobulinemia in Very Elderly (≥75-year-old) Patients: A 33-year-retrospective Cohort Study in an Italian University Hospital by Nicolò Danesin, Mariella Lo Schirico, Greta Scapinello, Angela Grassi, Marcello Riva, Tamara Berno, Antonio Branca, Andrea Visentin, Marco Carraro, Laura Pavan, Sabrina Manni, Laura Bonaldi, Annalisa Martines, Roberta Bertorelle, Fabrizio Vianello, Carmela Gurrieri, Chiara Briani, Renato Zambello, Livio Trentin, Francesco Piazza

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P549: EFFICACY AND TOXICITY OF CPX-351 IN PATIENTS WITH HIGH-RISK ACUTE MYELOID LEUKEMIA (AML): THE MULTICENTER REAL-WORLD EXPERIENCE FROM THE “ITALIAN TRIVENETO REGISTRY”. by Gian Luca Morelli, Carla Fili, Endri Mauro, Anna Maria Scattolin, Federico Mosna, Carmela Gurrieri, Gianpaolo Nadali, Albana Lico, Alessandra Sperotto, Eleonora DE Bellis, Mariagrazia Michieli, Teresa Aloisi, Davide Lazzarotto, Maria Elena Zannier, Erica Simeone, Daniel Alzetta, Giulia Battaglia, Chiara Callegari, Umberto Pizzano, Rikard Mullai, Luca Tosoni, Mario Tiribelli, Renato Fanin

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CK2β Regulates Hematopoietic Stem Cell Biology and Erythropoiesis by Laura Quotti Tubi, Sara Canovas Nunes, Elisa Mandato, Marco Pizzi, Nicola Vitulo, Mirco D’Agnolo, Raffaella Colombatti, Maddalena Martella, Maria Paola Boaro, Elena Doriguzzi Breatta, Anna Fregnani, Zaira Spinello, Mitja Nabergoj, Odile Filhol, Brigitte Boldyreff, Mattia Albiero, Gian Paolo Fadini, Carmela Gurrieri, Fabrizio Vianello, Gianpietro Semenzato, Sabrina Manni, Livio Trentin, Francesco Piazza

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Tixagevimab/Cilgavimab as pre-exposure prophylaxis against SARS-CoV-2 in patients with hematological malignancies by Francesco Angotzi, Marco Petrella, Tamara Berno, Gianni Binotto, Giorgia Bonetto, Antonio Branca, Marco Carraro, Chiara Adele Cavaretta, Alessandro Cellini, Fabio D’Amore, Laura Forlani, Ilaria Gianesello, Carmela Gurrieri, Silvia Imbergamo, Federica Lessi, Antonio Maroccia, Federica Mazzetto, Laura Pavan, Sara Pezone, Francesco Piazza, Stefano Pravato, Valeria Ruocco, Greta Scapinello, Fabrizio Vianello, Renato Zambello, Ivan Zatta, Simone Zoletto, Andrea Padoan, Livio Trentin, Andrea Visentin

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Blinatumomab and Inotuzumab Ozogamicin Sequential Use for the Treatment of Relapsed/Refractory Acute Lymphoblastic Leukemia: A Real-Life Campus All Study by Nicola Stefano Fracchiolla, Mariarita Sciumè, Cristina Papayannidis, Antonella Vitale, Sabina Chiaretti, Mario Annunziata, Fabio Giglio, Prassede Salutari, Fabio Forghieri, Davide Lazzarotto, Monia Lunghi, Annalisa Imovilli, Barbara Scappini, Massimiliano Bonifacio, Michelina Dargenio, Carmela Gurrieri, Elisabetta Todisco, Marzia Defina, Maria Ilaria Del Principe, Patrizia Zappasodi, Marco Cerrano, Lidia Santoro, Elena Tagliaferri, Enrico Barozzi, Pasquale De Roberto, Marta Canzi, Elisa Buzzatti, Chiara Sartor, Francesco Passamonti, Robin Foà, Antonio Curti

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