FGF/FGFR genomic amplification as a predictive biomarker for immune checkpoint blockade resistance: a short report by Francois Ghiringhelli, Caroline Truntzer, Julie Lecuelle, Nicolas Roussot, Lorraine Dalens

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Interleukin-1α as a Potential Prognostic Biomarker in Pancreatic Cancer by Leonardo Gigante, Gwladys Gaudillière-Le Dain, Aurélie Bertaut, Caroline Truntzer, François Ghiringhelli

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Predictive Factors of Local Recurrence after Colorectal Cancer Liver Metastases Thermal Ablation by Julien Odet, Julie Pellegrinelli, Olivier Varbedian, Caroline Truntzer, Marco Midulla, François Ghiringhelli, David Orry

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Evaluation of tumor immune contexture among intrinsic molecular subtypes helps to predict outcome in early breast cancer by Francois Ghiringhelli, Valentin Derangere, Quentin Klopfenstein, Emeric Limagne, Marion Thibaudin, Caroline Truntzer, Laurent Arnould, Sylvain Ladoire

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Toward the Identification of Two Glycoproteins Involved in the Stomatal Deregulation of Downy Mildew–Infected Grapevine Leaves by Christelle Guillier, Magdalena Gamm, Géraldine Lucchi, Caroline Truntzer, Delphine Pecqueur, Patrick Ducoroy, Marielle Adrian, Marie-Claire Héloir

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The bacterial species profiles of the lingual and salivary microbiota differ with basic tastes sensitivity in human by Hélène Licandro, Caroline Truntzer, Sébastien Fromentin, Christian Morabito, Benoit Quinquis, Nicolas Pons, Christophe Martin, Hervé M. Blottière, Eric Neyraud

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Protein Kinase Inhibitor-Mediated Immunoprophylactic and Immunotherapeutic Control of Colon Cancer by Silvia Ghione, Silvia Ghione, Cindy Racoeur, Cindy Racoeur, Nesrine Mabrouk, Nesrine Mabrouk, Jingxuan Shan, Emma Groetz, Emma Groetz, Elise Ballot, Elise Ballot, Caroline Truntzer, Caroline Truntzer, Lotfi Chouchane, Frédérique Végran, Frédérique Végran, Frédérique Végran, Catherine Paul, Catherine Paul, Stéphanie Plenchette, Stéphanie Plenchette, Ali Bettaieb, Ali Bettaieb

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MER4 endogenous retrovirus correlated with better efficacy of anti-PD1/PD-L1 therapy in non-small cell lung cancer by Francois Ghiringhelli, Romain Boidot, Caroline Truntzer, Bertrand Routy, Philippe Joubert, Julie Lecuelle, Laure Favier, Cléa Fraisse, Aurélie Lagrange, Coureche Kaderbhai, Sandy Chevrier

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CD3-CD8 immune score associated with a clinical score stratifies PDAC prognosis regardless of adjuvant or neoadjuvant chemotherapy by Coralie Schoumacher, Valentin Derangère, Gwladys Gaudillière-Le Dain, Titouan Huppe, David Rageot, Alis Ilie, Angélique Vienot, Christophe Borg, Franck Monnien, Frederic Bibeau, Caroline Truntzer, François Ghiringhelli

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Machine learning evaluation of immune infiltrate through digital tumour score allows prediction of survival outcome in a pooled analysis of three international stage III colon canc... by Julie Lecuelle, Caroline Truntzer, Debora Basile, Luigi Laghi, Luana Greco, Alis Ilie, David Rageot, Jean-François Emile, Fréderic Bibeau, Julien Taïeb, Valentin Derangere, Come Lepage, François Ghiringhelli

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Deep Multiple Instance Learning Model to Predict Outcome of Pancreatic Cancer Following Surgery by Caroline Truntzer, Dina Ouahbi, Titouan Huppé, David Rageot, Alis Ilie, Chloe Molimard, Françoise Beltjens, Anthony Bergeron, Angelique Vienot, Christophe Borg, Franck Monnien, Frédéric Bibeau, Valentin Derangère, François Ghiringhelli

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SALL4‐related gene signature defines a specific stromal subset of pancreatic ductal adenocarcinoma with poor prognostic features by Angélique Vienot, Franck Monnien, Caroline Truntzer, Virginie Mougey, Adeline Bouard, Jean‐René Pallandre, Chloé Molimard, Romain Loyon, Kamal Asgarov, Gerlinde Averous, François Ghiringhelli, Frédéric Bibeau, Paul Peixoto, Christophe Borg

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Molecular intrinsic subtypes, genomic, and immune landscapes of BRCA-proficient but HRD-high ER-positive/HER2-negative early breast cancers by Elise Ballot, Loïck Galland, Hugo Mananet, Romain Boidot, Laurent Arnould, Isabelle Desmoulins, Didier Mayeur, Courèche Kaderbhai, Silvia Ilie, Audrey Hennequin, Anthony Bergeron, Valentin Derangère, François Ghiringhelli, Caroline Truntzer, Sylvain Ladoire

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Efficacy of platinum-based chemotherapy in metastatic breast cancer and HRD biomarkers: utility of exome sequencing by Loïck Galland, Elise Ballot, Hugo Mananet, Romain Boidot, Julie Lecuelle, Juliette Albuisson, Laurent Arnould, Isabelle Desmoulins, Didier Mayeur, Courèche Kaderbhai, Silvia Ilie, Audrey Hennequin, Anthony Bergeron, Valentin Derangère, François Ghiringhelli, Caroline Truntzer, Sylvain Ladoire

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Real-world prevalence, treatment and survival of “high risk” early breast cancer, with mandatory testing of gBRCA1/2 mutation according to the OlympiA trial inclusion criteria: Dat... by Sylvain Ladoire, Ariane Mamguem Kamga, Loick Galland, Isabelle Desmoulins, Didier Mayeur, Courèche Kaderbhai, Silvia Mihaelia Ilie, Audrey Hennequin, Clementine Jankowski, Juliette Albuisson, Sophie Nambot, Charles Coutant, Laurent Arnould, Manon Reda, Caroline Truntzer, Sandrine Dabakuyo

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Follicular helper-T cells restore CD8+-dependent antitumor immunity and anti-PD-L1/PD-1 efficacy by Francois Ghiringhelli, Valentin Derangere, Marion Thibaudin, Caroline Truntzer, Bertrand Routy, Fanny Chalmin, Cédric Rébé, Julie Niogret, Hélène Berger, Romain Mary, Elise Ballot, Christophe Hibos, Léa Hampe, David Rageot, Théo Accogli, Philippe Joubert, James Harker, Frederique Vegran

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Safety and efficacy of trifluridine/tipiracil +/− bevacizumab plus XB2001 (anti-IL-1α antibody): a single-center phase 1 trial by Marion Thibaudin, Nicolas Roussot, Chloé Burlot, Antonin Schmitt, Julie Vincent, Zoé Tharin, Leila Bengrine, Hélène Bellio, Aurélie Bertaut, Léa Hampe, Susy Daumoine, Emilie Rederstorff, Morgane Peroz, Titouan Huppe, Valentin Derangère, David Rageot, John Simard, Caroline Truntzer, Jean David Fumet, Francois Ghiringhelli

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Peroxisomal defects in microglial cells induce a disease-associated microglial signature by Quentin Raas, Ali Tawbeh, Mounia Tahri-Joutey, Mounia Tahri-Joutey, Catherine Gondcaille, Céline Keime, Romain Kaiser, Doriane Trompier, Boubker Nasser, Valerio Leoni, Emma Bellanger, Maud Boussand, Yannick Hamon, Alexandre Benani, Francesca Di Cara, Caroline Truntzer, Mustapha Cherkaoui-Malki, Pierre Andreoletti, Stéphane Savary

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The DAV132 colon-targeted adsorbent does not interfere with plasma concentrations of antibiotics but prevents antibiotic-related dysbiosis: a randomized phase I trial in healthy vo... by Meriem Messaoudene, Stéphanie Ferreira, Nathalie Saint-Lu, Mayra Ponce, Caroline Truntzer, Romain Boidot, Clément Le Bescop, Thomas Loppinet, Tanguy Corbel, Céline Féger, Karine Bertrand, Arielle Elkrief, Morten Isaksen, Fabien Vitry, Frédérique Sablier-Gallis, Antoine Andremont, Lloyd Bod, François Ghiringhelli, Jean de Gunzburg, Bertrand Routy

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Downregulation of Elovl5 promotes breast cancer metastasis through a lipid-droplet accumulation-mediated induction of TGF-β receptors by Trinh-Le-Vi Kieu, Léa Pierre, Valentin Derangère, Sabrina Perrey, Caroline Truntzer, Antoine Jalil, Sébastien Causse, Emma Groetz, Adélie Dumont, Laura Guyard, Laurent Arnould, Jean-Paul Pais de Barros, Lionel Apetoh, Cédric Rébé, Emeric Limagne, Tony Jourdan, Laurent Demizieux, David Masson, Charles Thomas, François Ghiringhelli, Mickaël Rialland

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