Modeling of pharmacokinetics of cocaine in human reveals the feasibility for development of enzyme therapies for drugs of abuse. by Fang Zheng, Chang-Guo Zhan

Get full text

Clinical data mining reveals analgesic effects of lapatinib in cancer patients by Shuo Zhou, Fang Zheng, Chang-Guo Zhan

Get full text

Development of pharmacotherapies for abdominal aortic aneurysms by Lauren M. Weaver, Charles D. Loftin, Chang-Guo Zhan

Get full text

Shexiang Baoxin Pill, a Proprietary Multi-Constituent Chinese Medicine, Prevents Locomotor and Cognitive Impairment Caused by Brain Ischemia and Reperfusion Injury in Rats: A Poten... by Zong-Shi Qin, Yu Zheng, Xi-Dan Zhou, Dong-Dong Shi, Dan Cheng, Chun Shum Shek, Chang-Sen Zhan, Chang-Sen Zhan, Zhang-Jin Zhang

Get full text

Effects of alcohol on metabolism and toxicity of cocaine in rats by Linyue Shang, Xirong Zheng, Ting Zhang, Jing Deng, Chang-Guo Zhan, Fang Zheng

Get full text

Catalytic activities of a highly efficient cocaine hydrolase for hydrolysis of biologically active cocaine metabolites norcocaine and benzoylecgonine by Linyue Shang, Zhenyu Jin, Huimei Wei, Shawn Park, Chang-Guo Zhan, Fang Zheng

Get full text

Long-lasting blocking of interoceptive effects of cocaine by a highly efficient cocaine hydrolase in rats by Huimei Wei, Johnathan E. LeSaint, Zhenyu Jin, Chang-Guo Zhan, Fang Zheng

Get full text

Data for high-throughput estimation of specific activities of enzyme/mutants in cell lysates through immunoturbidimetric assay of proteins by Yiran Feng, Xiaolan Yang, Huimin Chong, Deqiang Wang, Xiaolei Hu, Chang-Guo Zhan, Fei Liao

Get full text

DREAM-in-CDM Approach and Identification of a New Generation of Anti-inflammatory Drugs Targeting mPGES-1 by Shuo Zhou, Ziyuan Zhou, Kai Ding, Yaxia Yuan, Charles Loftin, Fang Zheng, Chang-Guo Zhan

Get full text

iMSCGnet: Iterative Multi-Scale Context-Guided Segmentation of Skin Lesion in Dermoscopic Images by Yujiao Tang, Zhiwen Fang, Shaofeng Yuan, Chang'An Zhan, Yanyan Xing, Joey Tianyi Zhou, Feng Yang

Get full text

Develop a High-Throughput Screening Method to Identify C-P4H1 (Collagen Prolyl 4-Hydroxylase 1) Inhibitors from FDA-Approved Chemicals by Shike Wang, Kuo-Hao Lee, Nathalia Victoria Araujo, Chang-Guo Zhan, Vivek M. Rangnekar, Ren Xu

Get full text

A highly selective mPGES-1 inhibitor to block abdominal aortic aneurysm progression in the angiotensin mouse model by Lauren M. Weaver, Madeline J. Stewart, Kai Ding, Charles D. Loftin, Fang Zheng, Chang-Guo Zhan

Get full text

Analgesic effects of a highly selective mPGES-1 inhibitor by Madeline J. Stewart, Lauren M. Weaver, Kai Ding, Annet Kyomuhangi, Charles D. Loftin, Fang Zheng, Chang-Guo Zhan

Get full text

Computational and experimental insights into the mechanism of substrate recognition and feedback inhibition of protoporphyrinogen oxidase. by Ge-Fei Hao, Ying Tan, Sheng-Gang Yang, Zhi-Fang Wang, Chang-Guo Zhan, Zhen Xi, Guang-Fu Yang

Get full text

Nicotine has no significant cytoprotective activity against SARS-CoV-2 infection. by Fang Zheng, Elena Lian, Gaby Ramirez, Carley McAlister, Shuo Zhou, Wen Zhang, Chunming Liu, Rushika Perera, Chang-Guo Zhan

Get full text

Gene transfer of mutant mouse cholinesterase provides high lifetime expression and reduced cocaine responses with no evident toxicity. by Liyi Geng, Yang Gao, Xiabin Chen, Shurong Hou, Chang-Guo Zhan, Zoran Radic, Robin J Parks, Stephen J Russell, Linh Pham, Stephen Brimijoin

Get full text

Epigenetic Regulation of Wnt Signaling by Carboxamide-Substituted Benzhydryl Amines that Function as Histone Demethylase Inhibitors by Wen Zhang, Vitaliy M. Sviripa, Yanqi Xie, Tianxin Yu, Meghan G. Haney, Jessica S. Blackburn, Charles A. Adeniran, Chang-Guo Zhan, David S. Watt, Chunming Liu

Get full text

Mutations of tyrosine 467 in the human norepinephrine transporter attenuate HIV-1 Tat-induced inhibition of dopamine transport while retaining physiological function. by Matthew J Strauss, Katherine D Porter, Pamela M Quizon, Sarah E Davis, Steven Lin, Yaxia Yuan, Gustavo A Martinez-Muniz, Wei-Lun Sun, Chang-Guo Zhan, Jun Zhu

Get full text

Mutations of tyrosine 467 in the human norepinephrine transporter attenuate HIV-1 Tat-induced inhibition of dopamine transport while retaining physiological function by Matthew J. Strauss, Katherine D. Porter, Pamela M. Quizon, Sarah E. Davis, Steven Lin, Yaxia Yuan, Gustavo A. Martinez-Muniz, Wei-Lun Sun, Chang-Guo Zhan, Jun Zhu

Get full text

Crystal Structure of 4-Hydroxyphenylpyruvate Dioxygenase in Complex with Substrate Reveals a New Starting Point for Herbicide Discovery by Hong-Yan Lin, Xi Chen, Jia-Nan Chen, Da-Wei Wang, Feng-Xu Wu, Song-Yun Lin, Chang-Guo Zhan, Jia-Wei Wu, Wen-Chao Yang, Guang-Fu Yang

Get full text