Charis Eng

Eng in 2011 Charis Eng (17 January 1962 – 13 August 2024) was a Singaporean American physician-scientist and geneticist at the Cleveland Clinic, notable for identifying the ''PTEN'' gene. She was the chairwoman and founding director of the Genomic Medicine Institute of the Cleveland Clinic, founding director and attending clinical cancer geneticist of the institute's clinical component, the Center for Personalized Genetic Healthcare, and professor and vice chairwoman of the Department of Genetics and Genome Sciences at Case Western Reserve University School of Medicine. Provided by Wikipedia
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  1. 1
    Transcriptome-(phospho)proteome characterization of brain of a germline model of cytoplasmic-predominant Pten expression with autism-like phenotypes

    Transcriptome-(phospho)proteome characterization of brain of a germline model of cytoplasmic-predominant Pten expression with autism-like phenotypes by Stetson Thacker, Charis Eng

    Published 2021-06-01
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  2. 2
    AP-2alpha induces epigenetic silencing of tumor suppressive genes and microsatellite instability in head and neck squamous cell carcinoma.

    AP-2alpha induces epigenetic silencing of tumor suppressive genes and microsatellite instability in head and neck squamous cell carcinoma. by Kristi L Bennett, Todd Romigh, Charis Eng

    Published 2009-09-01
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  3. 3
    Are population level familial risks and germline genetics meeting each other?

    Are population level familial risks and germline genetics meeting each other? by Kari Hemminki, Xinjun Li, Asta Försti, Charis Eng

    Published 2023-03-01
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  4. 4
    Integrative genomic analysis reveals extended germline homozygosity with lung cancer risk in the PLCO cohort.

    Integrative genomic analysis reveals extended germline homozygosity with lung cancer risk in the PLCO cohort. by Mohammed S Orloff, Li Zhang, Gurkan Bebek, Charis Eng

    Published 2012-01-01
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  5. 5
    Integrating somatic CNV and gene expression in breast cancers from women with PTEN hamartoma tumor syndrome

    Integrating somatic CNV and gene expression in breast cancers from women with PTEN hamartoma tumor syndrome by Takae Brewer, Lamis Yehia, Peter Bazeley, Charis Eng

    Published 2023-07-01
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  6. 6
    Germline nuclear-predominant Pten murine model exhibits impaired social and perseverative behavior, microglial activation, and increased oxytocinergic activity

    Germline nuclear-predominant Pten murine model exhibits impaired social and perseverative behavior, microglial activation, and increased oxytocinergic activity by Nick Sarn, Stetson Thacker, Hyunpil Lee, Charis Eng

    Published 2021-06-01
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  7. 7
    The mitochondrial genome as a modifier of autism versus cancer phenotypes in PTEN hamartoma tumor syndrome

    The mitochondrial genome as a modifier of autism versus cancer phenotypes in PTEN hamartoma tumor syndrome by Ruipeng Wei, Lamis Yehia, Ying Ni, Charis Eng

    Published 2023-07-01
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  8. 8
    Non-canonical role of wild-type SEC23B in the cellular stress response pathway

    Non-canonical role of wild-type SEC23B in the cellular stress response pathway by Lamis Yehia, Darren Liu, Shuai Fu, Pranav Iyer, Charis Eng

    Published 2021-03-01
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  9. 9
    Formative Evaluation of Clinician Experience with Integrating Family History-Based Clinical Decision Support into Clinical Practice

    Formative Evaluation of Clinician Experience with Integrating Family History-Based Clinical Decision Support into Clinical Practice by Megan Doerr, Emily Edelman, Emily Gabitzsch, Charis Eng, Kathryn Teng

    Published 2014-03-01
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  10. 10
    Comprehensive germline genomic profiles of children, adolescents and young adults with solid tumors

    Comprehensive germline genomic profiles of children, adolescents and young adults with solid tumors by Sara Akhavanfard, Roshan Padmanabhan, Lamis Yehia, Feixiong Cheng, Charis Eng

    Published 2020-05-01
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  11. 11
    Linkage disequilibrium between two high-frequency deletion polymorphisms: implications for association studies involving the glutathione-S transferase (GST) genes.

    Linkage disequilibrium between two high-frequency deletion polymorphisms: implications for association studies involving the glutathione-S transferase (GST) genes. by Yongzhong Zhao, Michael Marotta, Evan E Eichler, Charis Eng, Hisashi Tanaka

    Published 2009-05-01
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  12. 12
    Genetic and molecular features of seizure-freedom following surgical resections for focal epilepsy: A pilot study

    Genetic and molecular features of seizure-freedom following surgical resections for focal epilepsy: A pilot study by Shreya Louis, Robyn M. Busch, Robyn M. Busch, Robyn M. Busch, Dennis Lal, Dennis Lal, Jennifer Hockings, Jennifer Hockings, Jennifer Hockings, Jennifer Hockings, Olivia Hogue, Marcia Morita-Sherman, Deborah Vegh, Imad Najm, Imad Najm, Chaitali Ghosh, Chaitali Ghosh, Peter Bazeley, Charis Eng, Charis Eng, Charis Eng, Charis Eng, Lara Jehi, Lara Jehi, Lara Jehi, Daniel M. Rotroff, Daniel M. Rotroff, Daniel M. Rotroff

    Published 2022-09-01
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  13. 13
    Characterization of immunomodulating agents from Staphylococcus aureus for priming immunotherapy in triple-negative breast cancers

    Characterization of immunomodulating agents from Staphylococcus aureus for priming immunotherapy in triple-negative breast cancers by Chin-Chih Liu, Matthew Wolf, Ruth Ortego, Dennis Grencewicz, Tammy Sadler, Charis Eng

    Published 2024-01-01
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  14. 14
    Maternal genetics influences fetal neurodevelopment and postnatal autism spectrum disorder-like phenotype by modulating in-utero immunosuppression

    Maternal genetics influences fetal neurodevelopment and postnatal autism spectrum disorder-like phenotype by modulating in-utero immunosuppression by Ritika Jaini, Matthew R. Wolf, Qi Yu, Alexander T. King, Thomas W. Frazier, Charis Eng

    Published 2021-06-01
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  15. 15
    Investigating the Link between Lynch Syndrome and Breast Cancer

    Investigating the Link between Lynch Syndrome and Breast Cancer by Megan Sheehan, Brandie Heald, Courtney Yanda, Erinn Downs Kelly, Stephen Grobmyer, Charis Eng, Matthew Kalady, Holly Pederson

    Published 2020-04-01
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  16. 16
    Individualized genetic network analysis reveals new therapeutic vulnerabilities in 6,700 cancer genomes.

    Individualized genetic network analysis reveals new therapeutic vulnerabilities in 6,700 cancer genomes. by Chuang Liu, Junfei Zhao, Weiqiang Lu, Yao Dai, Jennifer Hockings, Yadi Zhou, Ruth Nussinov, Charis Eng, Feixiong Cheng

    Published 2020-02-01
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  17. 17
    My personal mutanome: a computational genomic medicine platform for searching network perturbing alleles linking genotype to phenotype

    My personal mutanome: a computational genomic medicine platform for searching network perturbing alleles linking genotype to phenotype by Yadi Zhou, Junfei Zhao, Jiansong Fang, William Martin, Lang Li, Ruth Nussinov, Timothy A. Chan, Charis Eng, Feixiong Cheng

    Published 2021-01-01
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  18. 18
    Brain single cell transcriptomic profiles in episodic memory phenotypes associated with temporal lobe epilepsy

    Brain single cell transcriptomic profiles in episodic memory phenotypes associated with temporal lobe epilepsy by Robyn M. Busch, Lamis Yehia, Bo Hu, Melissa Goldman, Bruce P. Hermann, Imad M. Najm, Steven A. McCarroll, Charis Eng

    Published 2022-11-01
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  19. 19
    Rapid Mutation Scanning of Genes Associated with Familial Cancer Syndromes Using Denaturing High-Performance Liquid Chromatography

    Rapid Mutation Scanning of Genes Associated with Familial Cancer Syndromes Using Denaturing High-Performance Liquid Chromatography by Deborah J. Marsh, George Theodosopoulos, Viive Howell, Anne-Louise Richardson, Diana E. Benn, Anné L. Proos, Charis Eng, Bruce G. Robinson

    Published 2001-01-01
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  20. 20
    A Bi-Institutional Study of Gastrointestinal and Hepatic Manifestations in Children With PTEN Hamartoma Tumor Syndrome

    A Bi-Institutional Study of Gastrointestinal and Hepatic Manifestations in Children With PTEN Hamartoma Tumor Syndrome by Darren Liu, Suzanne P. MacFarland, Lamis Yehia, Melani M. Duvall, Petar Mamula, Jacob A. Kurowski, Colleen S. Greene, Kadakkal Radhakrishnan, Charis Eng

    Published 2024-01-01
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