CRISPR Gene Therapy: Applications, Limitations, and Implications for the Future by Fathema Uddin, Charles M. Rudin, Charles M. Rudin, Triparna Sen, Triparna Sen

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Co-targeting TGF-β and PD-L1 with radiation therapy: The Goldilocks principle by Samuel F. Bakhoum, Charles M. Rudin

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Role of CD38 in anti-tumor immunity of small cell lung cancer by Hirokazu Taniguchi, Hirokazu Taniguchi, Shweta S. Chavan, Andrew Chow, Joseph M. Chan, Joseph M. Chan, Hiroshi Mukae, Charles M. Rudin, Charles M. Rudin, Triparna Sen

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Quantitation of Murine Stroma and Selective Purification of the Human Tumor Component of Patient-Derived Xenografts for Genomic Analysis. by Valentina E Schneeberger, Viola Allaj, Eric E Gardner, J T Poirier, Charles M Rudin

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An optimized NGS sample preparation protocol for in vitro CRISPR screens by Corrin A. Wohlhieter, Fathema Uddin, Àlvaro Quintanal-Villalonga, John T. Poirier, Triparna Sen, Charles M. Rudin

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IL-18–secreting CAR T cells targeting DLL3 are highly effective in small cell lung cancer models by Janneke E. Jaspers, Jonathan F. Khan, William D. Godfrey, Andrea V. Lopez, Metamia Ciampricotti, Charles M. Rudin, Renier J. Brentjens

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Target engagement imaging of PARP inhibitors in small-cell lung cancer by Brandon Carney, Susanne Kossatz, Benjamin H. Lok, Valentina Schneeberger, Kishore K. Gangangari, Naga Vara Kishore Pillarsetty, Wolfgang A. Weber, Charles M. Rudin, John T. Poirier, Thomas Reiner

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Protocol to dissociate, process, and analyze the human lung tissue using single-cell RNA-seq by Álvaro Quintanal-Villalonga, Joseph M. Chan, Ignas Masilionis, Vianne Ran Gao, Yubin Xie, Viola Allaj, Andrew Chow, John T. Poirier, Dana Pe’er, Charles M. Rudin, Linas Mazutis

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Emerging therapies targeting the delta-like ligand 3 (DLL3) in small cell lung cancer by Charles M. Rudin, Martin Reck, Melissa L. Johnson, Fiona Blackhall, Christine L. Hann, James Chih-Hsin Yang, Julie M. Bailis, Gwyn Bebb, Amanda Goldrick, John Umejiego, Luis Paz-Ares

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Hedgehog signaling pathway is active in GBM with GLI1 mRNA expression showing a single continuous distribution rather than discrete high/low clusters. by Vikas Chandra, Tapojyoti Das, Puneet Gulati, Nidhan K Biswas, Sarang Rote, Uttara Chatterjee, Samarendra N Ghosh, Sumit Deb, Suniti K Saha, Anup K Chowdhury, Subhashish Ghosh, Charles M Rudin, Ankur Mukherjee, Analabha Basu, Surajit Dhara

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Antibiotics are associated with worse outcomes in lung cancer patients treated with chemotherapy and immunotherapy by Arielle Elkrief, Eder Orlando Méndez-Salazar, Jade Maillou, Chad M. Vanderbilt, Pooja Gogia, Antoine Desilets, Meriem Messaoudene, Daniel Kelly, Marc Ladanyi, Matthew D. Hellmann, Laurence Zitvogel, Charles M. Rudin, Bertrand Routy, Lisa Derosa, Adam J. Schoenfeld

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Correction: SMARCA4 controls state plasticity in small cell lung cancer through regulation of neuroendocrine transcription factors and REST splicing by Esther Redin, Harsha Sridhar, Yingqian A. Zhan, Barbara Pereira Mello, Hong Zhong, Vidushi Durani, Amin Sabet, Parvathy Manoj, Irina Linkov, Juan Qiu, Richard P. Koche, Elisa de Stanchina, Maider Astorkia, Doron Betel, Álvaro Quintanal-Villalonga, Charles M. Rudin

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SMARCA4 controls state plasticity in small cell lung cancer through regulation of neuroendocrine transcription factors and REST splicing by Esther Redin, Harsha Sridhar, Yingqian A. Zhan, Barbara Pereira Mello, Hong Zhong, Vidushi Durani, Amin Sabet, Parvathy Manoj, Irina Linkov, Juan Qiu, Richard P. Koche, Elisa de Stanchina, Maider Astorkia, Doron Betel, Álvaro Quintanal-Villalonga, Charles M. Rudin

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Factors influencing the utilization of prophylactic cranial irradiation in patients with limited-stage small cell lung cancer by Benjamin H. Lok, MD, Jennifer Ma, BA, Amanda Foster, BS, Carmen A. Perez, MD, PhD, Weiji Shi, MS, Zhigang Zhang, PhD, Bob T. Li, MD, MPH, Charles M. Rudin, MD, PhD, Andreas Rimner, MD, Abraham J. Wu, MD

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Regulation of neuroendocrine plasticity by the RNA-binding protein ZFP36L1 by Hsiao-Yun Chen, Yavuz T. Durmaz, Yixiang Li, Amin H. Sabet, Amir Vajdi, Thomas Denize, Emily Walton, Yasmin Nabil Laimon, John G. Doench, Navin R. Mahadevan, Julie-Aurore Losman, David A. Barbie, Michael Y. Tolstorukov, Charles M. Rudin, Triparna Sen, Sabina Signoretti, Matthew G. Oser

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Genomic and transcriptomic analysis of a diffuse pleural mesothelioma patient-derived xenograft library by Michael Offin, Jennifer L. Sauter, Sam E. Tischfield, Jacklynn V. Egger, Shweta Chavan, Nisargbhai S. Shah, Parvathy Manoj, Katia Ventura, Viola Allaj, Elisa de Stanchina, William Travis, Marc Ladanyi, Andreas Rimner, Valerie W. Rusch, Prasad S. Adusumilli, John T. Poirier, Marjorie G. Zauderer, Charles M. Rudin, Triparna Sen

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Concurrent Mutations in STK11 and KEAP1 Promote Ferroptosis Protection and SCD1 Dependence in Lung Cancer by Corrin A. Wohlhieter, Allison L. Richards, Fathema Uddin, Christopher H. Hulton, Àlvaro Quintanal-Villalonga, Axel Martin, Elisa de Stanchina, Umeshkumar Bhanot, Marina Asher, Nisargbhai S. Shah, Omar Hayatt, Darren J. Buonocore, Natasha Rekhtman, Ronglai Shen, Kathryn C. Arbour, Mark Donoghue, John T. Poirier, Triparna Sen, Charles M. Rudin

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WEE1 inhibition enhances the antitumor immune response to PD-L1 blockade by the concomitant activation of STING and STAT1 pathways in SCLC by Hirokazu Taniguchi, Rebecca Caeser, Shweta S. Chavan, Yingqian A. Zhan, Andrew Chow, Parvathy Manoj, Fathema Uddin, Hidenori Kitai, Rui Qu, Omar Hayatt, Nisargbhai S. Shah, Álvaro Quintanal Villalonga, Viola Allaj, Evelyn M. Nguyen, Joseph Chan, Adam O. Michel, Hiroshi Mukae, Elisa de Stanchina, Charles M. Rudin, Triparna Sen

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Molecular classification and biomarkers of outcome with immunotherapy in extensive-stage small-cell lung cancer: analyses of the CASPIAN phase 3 study by Mingchao Xie, Miljenka Vuko, Jaime Rodriguez-Canales, Johannes Zimmermann, Markus Schick, Cathy O’Brien, Luis Paz-Ares, Jonathan W. Goldman, Marina Chiara Garassino, Carl M. Gay, John V. Heymach, Haiyi Jiang, J. Carl Barrett, Ross A. Stewart, Zhongwu Lai, Lauren A. Byers, Charles M. Rudin, Yashaswi Shrestha

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A Hyperactive Signalosome in Acute Myeloid Leukemia Drives Addiction to a Tumor-Specific Hsp90 Species by Hongliang Zong, Alexander Gozman, Eloisi Caldas-Lopes, Tony Taldone, Eric Sturgill, Sarah Brennan, Stefan O. Ochiana, Erica M. Gomes-DaGama, Siddhartha Sen, Anna Rodina, John Koren III, Michael W. Becker, Charles M. Rudin, Ari Melnick, Ross L. Levine, Gail J. Roboz, Stephen D. Nimer, Gabriela Chiosis, Monica L. Guzman

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