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USP28 deletion and small molecule inhibition destabilises c-MYC and elicits regression of squamous cell lung carcinoma by Ruiz, EJ, Pinto-Fernandez, A, Turnbull, AP, Lan, L, Charlton, TM, Scott, HC, Damianou, A, Vere, G, Riising, EM, Da Costa, C, Krajewski, WW, Guerin, D, Kearns, JD, Ioannidis, S, Katz, M, McKinnon, C, O'Connell, J, Moncaut, N, Rosewell, I, Nye, E, Jones, N, Heride, C, Gersch, M, Wu, M, Dinsmore, CJ, Hammonds, TR, Kim, S, Komander, D, Urbe, S, Clague, MJ, Kessler, BM, Behrens, A
Published 2021Journal article -
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Molecular basis of USP7 inhibition by selective small-molecule inhibitors. by Turnbull, AP, Ioannidis, S, Krajewski, WW, Pinto-Fernandez, A, Heride, C, Martin, ACL, Tonkin, LM, Townsend, EC, Buker, SM, Lancia, DR, Caravella, JA, Toms, AV, Charlton, TM, Lahdenranta, J, Wilker, E, Follows, BC, Evans, NJ, Stead, L, Alli, C, Zarayskiy, VV, Talbot, AC, Buckmelter, AJ, Wang, M, McKinnon, CL, Saab, F, McGouran, JF, Century, H, Gersch, M, Pittman, MS, Marshall, CG, Raynham, TM, Simcox, M, Stewart, LMD, McLoughlin, SB, Escobedo, JA, Bair, KW, Dinsmore, CJ, Hammonds, TR, Kim, S, Urbé, S, Clague, MJ, Kessler, BM, Komander, D
Published 2017Journal article