Posterior reversible encephalopathy syndrome in a B-cell acute lymphoblastic leukemia young adult patient treated with a pediatric-like chemotherapeutic schedule by Cristina Papayannidis, Francesca Volpato, Ilaria Iacobucci, Maria Chiara Abbenante, Chiara Sartor, Giovanni Martinelli

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Recurrent gastrointestinal hemorrhage in treatment with dasatinib in a patient showing SMAD4 mutation with acute lymphoblastic leukemia Philadelphia positive and juvenile polyposis... by Chiara Sartor, Cristina Papayannidis, Maria Chiara Abbenante, Ilaria Iacobucci, Alessandro Broccoli, Claudia Venturi, Nicoletta Testoni, Anna Ferrari, Giovanni Martinelli

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A case report of acute myeloid leukemia and neurofibromatosis 1 by Chiara Sartor, Cristina Papayannidis, Maria Chiara Abbenante, Antonio Curti, Nicola Polverelli, Emanuela Ottaviani, Ilaria Iacobucci, Viviana Guadagnuolo, Giovanni Martinelli

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P558: ABSOLUTE LYMPHOCYTE COUNT IS AN INDEPENDENT SURVIVAL PREDICTOR COMPARED TO MINIMAL RESIDUAL DISEASE IN PATIENTS WITH ACUTE MYELOID LEUKEMIA TREATED WITH INTENSIVE CHEMOTHERAP... by Gianluca Cristiano, Jacopo Nanni, Letizia Zannoni, Federico Zingarelli, Chiara Sartor, Parisi Sarah, Stefania Paolini, Cristina Papayannidis, Michele Cavo, Antonio Curti

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Combined Inhibition of Polo-Like Kinase-1 and Wee1 as a New Therapeutic Strategy to Induce Apoptotic Cell Death in Neoplastic Mast Cells by Manuela Mancini, Cecilia Monaldi, Sara De Santis, Michela Rondoni, Cristina Papayannidis, Chiara Sartor, Antonio Curti, Samantha Bruno, Michele Cavo, Simona Soverini

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PB1858: PROGNOSIS AND TREATMENT OF FLT3 MUTATED MYELOID SARCOMA IN THE ERA OF FLT3 INHIBITORS: RETROSPECTIVE EVALUATION IN 5 ITALIAN CENTERS. by Federica Lessi, Erika Borlenghi, Chiara Sartor, Calogero Vetro, Ernesta Audisio, Federico Vincenzo, Andrea Visentin, Federica Loscocco, Carmela Gurrieri, Livio Trentin, Felicetto Ferrara

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Rationale for a pediatric-inspired approach in the adolescent and young adult population with acute lymphoblastic leukemia, with a focus on asparaginase treatment by Carmelo Rizzari, Maria Caterina Putti, Antonella Colombini, Sara Casagranda, Giulia Maria Ferrari, Cristina Papayannidis, Ilaria Iacobucci, Maria Chiara Abbenante, Chiara Sartor, Giovanni Martinelli

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Ceftolozane-Tazobactam Treatment of Hypervirulent Multidrug Resistant <i>Pseudomonas aeruginosa</i> Infections in Neutropenic Patients by Paolo E. Coppola, Paolo Gaibani, Chiara Sartor, Simone Ambretti, Russell E. Lewis, Claudia Sassi, Marco Pignatti, Stefania Paolini, Antonio Curti, Fausto Castagnetti, Margherita Ursi, Michele Cavo, Marta Stanzani

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PB1865: NPM1-MUT MONITORING DURING GILTERITINIB TREATMENT IDENTIFIES DIFFERENT DYNAMICAL PATTERNS IN RESPONSIVE PATIENTS by Chiara Sartor, Emanuela Ottaviani, Jacopo Nanni, Raffaele Ciruolo, Gianluca Cristiano, Letizia Zannoni, Federico Zingarelli, Lorenza Bandini, Agnese Patuelli, Claudia Venturi, Valentina Robustellu, Dorian Forte, Michele Cavo, Antonio Curti, Cristina Papayannidis

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P371: PONATINIB AS A PROPHYLACTIC OR PRE-EMPTIVE STRATEGY TO PREVENT CYTOLOGICAL RELAPSE AFTER ALLO-SCT IN PATIENTS WITH PH POS ALL TRANSPLANTED IN COMPLETE CYTOLOGICAL REMISSION by Anna Candoni, Patrizia Chiusolo, Davide Lazzarotto, Cristina Papayannidis, Cristina Skert, Fabio Giglio, Nicola Stefano Fracchiolla, Michelina Dargenio, Sabina Chiaretti, Silvia Trappolini, Chiara Sartor, Paola Bresciani, Angela Cuoghi, Attilio Olivieri, Renato Fanin

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SETD2 non genomic loss of function in advanced systemic mastocytosis is mediated by an Aurora kinase A/MDM2 axis and can be therapeutically targeted by Manuela Mancini, Cecilia Monaldi, Sara De Santis, Cristina Papayannidis, Michela Rondoni, Chiara Sartor, Samantha Bruno, Livio Pagano, Marianna Criscuolo, Roberta Zanotti, Massimiliano Bonifacio, Patrizia Tosi, Michel Arock, Peter Valent, Michele Cavo, Simona Soverini

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Inotuzumab ozogamicin is effective in relapsed/refractory extramedullary B acute lymphoblastic leukemia by Luca Bertamini, Jacopo Nanni, Giovanni Marconi, Mariachiara Abbenante, Valentina Robustelli, Francesco Bacci, Antonella Matti, Stefania Paolini, Chiara Sartor, Silvia Lo Monaco, Maria Chiara Fontana, Stefano De Polo, Michele Cavo, Antonio Curti, Giovanni Martinelli, Cristina Papayannidis

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The ALLgorithMM: How to define the hemodilution of bone marrow samples in lymphoproliferative diseases by Ilaria Vigliotta, Ilaria Vigliotta, Silvia Armuzzi, Silvia Armuzzi, Martina Barone, Martina Barone, Vincenza Solli, Vincenza Solli, Ignazia Pistis, Enrica Borsi, Enrica Borsi, Barbara Taurisano, Barbara Taurisano, Gaia Mazzocchetti, Gaia Mazzocchetti, Marina Martello, Marina Martello, Andrea Poletti, Andrea Poletti, Chiara Sartor, Chiara Sartor, Ilaria Rizzello, Ilaria Rizzello, Lucia Pantani, Paola Tacchetti, Cristina Papayannidis, Katia Mancuso, Katia Mancuso, Serena Rocchi, Serena Rocchi, Elena Zamagni, Elena Zamagni, Antonio Curti, Antonio Curti, Mario Arpinati, Mario Arpinati, Michele Cavo, Michele Cavo, Carolina Terragna

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P375: INOTUZUMB OZOGAMICIN PRIOR TO ALLOGENEIC HEMATOPOIETIC STEM CELL TRANSPLANTATION IN RELAPSED OR REFRACTORY ACUTE B-LYMPHOBLASTIC LEUKEMIA by Sabine Kayser, Chiara Sartor, Fabio Giglio, Alessandro Bruno, Jonathan Webster, Patrizia Chiusolo, Francesco Saraceni, Selene Guerzoni, Lara Pochintesta, Erika Borlenghi, Giovanni Marconi, Irene Zacheo, Marco Cerrano, Prassede Salutari, Francesco Restuccia, Mariachiara Abbenante, Mark J Levis, Richard Schlenk, Cristina Papayannidis

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Synergism Through WEE1 and CHK1 Inhibition in Acute Lymphoblastic Leukemia by Andrea Ghelli Luserna Di Rorà, Matteo Bocconcelli, Anna Ferrari, Carolina Terragna, Samantha Bruno, Enrica Imbrogno, Neil Beeharry, Valentina Robustelli, Martina Ghetti, Roberta Napolitano, Gabriella Chirumbolo, Giovanni Marconi, Cristina Papayannidis, Stefania Paolini, Chiara Sartor, Giorgia Simonetti, Timothy J. Yen, Giovanni Martinelli

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PB1840: OUTCOME OF ADULT ACUTE MYELOID LEUKEMIA PATIENTS WITH EXTRAMEDULLARY DISEASE AFTER TREATMENT WITH VENETOCLAX/HYPOMETHYLATING AGENTS by Sabine Kayser, Khaled Sanber, Giovanni Marconi, Agnese Mattei, Marlise Luskin, Amar Kelkar, Marco Cerrano, Chiara Sartor, Fabio Giglio, Marta Riva, Lorenzo Rizzo, Francesco Saraceni, Selene Guerzoni, Federica Lessi, Erika Borlenghi, Alexander Perl, Mark J Levis, Cristina Papayannidis, Tania Jain, Richard Schlenk

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Case Report: A Novel Activating FLT3 Mutation in Acute Myeloid Leukemia by Samantha Bruno, Lorenza Bandini, Agnese Patuelli, Valentina Robustelli, Valentina Robustelli, Claudia Venturi, Manuela Mancini, Dorian Forte, Sara De Santis, Cecilia Monaldi, Alessandra Grassi, Gabriella Chiurumbolo, Stefania Paolini, Gianluca Cristiano, Cristina Papayannidis, Chiara Sartor, Jacopo Nanni, Emanuela Ottaviani, Antonio Curti, Michele Cavo, Michele Cavo, Simona Soverini

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Assessment of liver stiffness measurement and ultrasound findings change during inotuzumab ozogamicin cycles for relapsed or refractory acute lymphoblastic leukemia by Federico Ravaioli, Giovanni Marconi, Giovanni Martinelli, Elton Dajti, Chiara Sartor, Maria Chiara Abbenante, Luigina Vanessa Alemanni, Jacopo Nanni, Benedetta Rossini, Sarah Parisi, Luigi Colecchia, Gianluca Cristiano, Giovanni Marasco, Amanda Vestito, Stefania Paolini, Francesca Bonifazi, Antonio Curti, Davide Festi, Michele Cavo, Antonio Colecchia, Cristina Papayannidis

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The baseline comorbidity burden affects survival in elderly patients with acute myeloid leukemia receiving hypomethylating agents: Results from a multicentric clinical study by Giovanni Marconi, Anna Candoni, Roberta Di Nicola, Chiara Sartor, Sarah Parisi, Mariachiara Abbenante, Jacopo Nanni, Gianluca Cristiano, Letizia Zannoni, Davide Lazzarotto, Benedetta Giannini, Carmen Baldazzi, Lorenza Bandini, Emanuela Ottaviani, Nicoletta Testoni, Chiara Di Giovanni Bezzi, Rania Abd‐alatif, Giulia Ciotti, Renato Fanin, Giovanni Martinelli, Stefania Paolini, Paolo Ricci, Michele Cavo, Cristina Papayannidis, Antonio Curti

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Targeting WEE1 to enhance conventional therapies for acute lymphoblastic leukemia by Andrea Ghelli Luserna Di Rorà, Neil Beeharry, Enrica Imbrogno, Anna Ferrari, Valentina Robustelli, Simona Righi, Elena Sabattini, Maria Vittoria Verga Falzacappa, Chiara Ronchini, Nicoletta Testoni, Carmen Baldazzi, Cristina Papayannidis, Maria Chiara Abbenante, Giovanni Marconi, Stefania Paolini, Sarah Parisi, Chiara Sartor, Maria Chiara Fontana, Serena De Matteis, Ilaria Iacobucci, Pier Giuseppe Pelicci, Michele Cavo, Timothy J. Yen, Giovanni Martinelli

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