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Chikashi Toyoshima
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Author
Chikashi Toyoshima
Chikashi Toyoshima
Chikashi Toyoshima
(,
Hepburn
: ; born July 17, 1954) is a Japanese
biophysicist
, a
professor
at the
University of Tokyo
and a Foreign Associate of the
National Academy of Sciences
in the
United States
. His research focuses on two
protein
s: the
Ca
2+
ATPase
, and the
Na
+
/ K
+
-ATPase
. Toyoshima's research about Ca
2+
ATPase started in 1989. He and his colleagues obtained the world's first series of images of Ca
2+
ATPase at the atomic level. He has determined the crystal structures of ten intermediates of Ca
2+
ATPase via
X-ray crystallography
,
cryogenic electron microscopy
(cryo-EM), among other methods. Toyoshima and
Poul Nissen
were awarded the
Gregori Aminoff Prize
in 2016 by
The Royal Swedish Academy of Sciences
for their fundamental contributions to understanding the structural basis for ATP-driven translocation of ions across membranes.
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Chikashi Toyoshima
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1
ATPase-dependent auto-phosphorylation of the open condensin hinge diminishes DNA binding
by
Yuko Akai
,
Ryuta Kanai
,
Norihiko Nakazawa
,
Masahiro Ebe
,
Chikashi Toyoshima
,
Mitsuhiro Yanagida
Published 2014-01-01
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Article
2
5-Hydroxymethylcytosine Plays a Critical Role in Glioblastomagenesis by Recruiting the CHTOP-Methylosome Complex
by
Hiroki Takai
,
Koji Masuda
,
Tomohiro Sato
,
Yuriko Sakaguchi
,
Takeo Suzuki
,
Tsutomu Suzuki
,
Ryo Koyama-Nasu
,
Yukiko Nasu-Nishimura
,
Yuki Katou
,
Haruo Ogawa
,
Yasuyuki Morishita
,
Hiroko Kozuka-Hata
,
Masaaki Oyama
,
Tomoki Todo
,
Yasushi Ino
,
Akitake Mukasa
,
Nobuhito Saito
,
Chikashi Toyoshima
,
Katsuhiko Shirahige
,
Tetsu Akiyama
Published 2014-10-01
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Article
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