China Kadoorie Biobank
The China Kadoorie Biobank is acquiring genomic data on half a million Chinese participants. In 2022 Genome-wide genotyping had been conducted for more than 100,000 participants using custom-designed Axiom arrays.It collected questionnaire and physical data and blood samples on 510,000 men and women aged between 30 and 79 from 10 regions in China between 2004-2008 with the aim of investigating chronic diseases (e.g. heart attack, stroke, diabetes, and cancer). Participants have been linked to mortality registers and nationwide health systems and a sub-group of 25,000 are retested every few years. It is a joint venture by the University of Oxford’s Clinical Trial Service Unit & Epidemiological Studies Unit and the Chinese Academy of Medical Sciences.
Research based on the biobank published by the American Thoracic Society in 2018 found that respiratory disease hospitalization or death were 36% higher among people who used wood or coal for cooking compared to those who used electricity or gas.
A study published in Heart based on the biobank found that people who ate an egg a day had a lower incidence of cardiovascular disease overall than those who ate no eggs. They had a 25% lower incidence of hemorrhagic stroke, and a 12% reduction in risk of ischemic heart disease.
A study published in 2022 examined the relative risk of mortality associated with five individual and combined lifestyle factors - never smoking or quitting not for illness, no excessive alcohol use, being physically active, healthy eating habits, and healthy body shape - and established that they could be associated with substantial gains in life expectancy in the Chinese population. Provided by Wikipedia
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Cardiovascular risk factors and Parkinson’s disease in 500,000 Chinese adults by Clarke, R, Lewington, S, Mappin‐Kasirer, B, Turnbull, I, Guo, Y, Bian, Z, Chen, Y, Yang, L, Chen, Z, Clarke, R, China Kadoorie Biobank
Published 2019Journal article -
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Trans-generational changes and rural-urban inequality in household fuel use and cookstove ventilation in China: a multi-region study of 0.5 million adults by Chan, K, Lam, K, Kurmi, O, Guo, Y, Bennett, D, Bian, Z, Sherliker, P, Chen, J, Li, L, Chen, Z, China Kadoorie Biobank Collaborative Group
Published 2017Journal article -
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Association of major depression with risk of ischemic heart disease in a mega-cohort of Chinese adults: the China Kadoorie Biobank Study by Liu, N, Pan, X, Yu, C, Lv, J, Guo, Y, Bian, Z, Yang, L, Chen, Y, Wu, T, Chen, Z, Pan, A, Li, L, China Kadoorie Biobank Collaborative Group
Published 2016Journal article -
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中国成年人睡眠时长、午睡与失眠症状的分布及关联研究 [Distributions and associations between duration of sleep, daytime naps and insomnia symptoms among Chinese adults]... by Zheng, B, Lin, L, Yu, C, Lyu, J, Guo, Y, Bian, Z, Tan, Y, Pei, P, Chen, J, Chen, Z, Li, L, China Kadoorie Biobank (CKB) Collaborative Group
Published 2017Journal article -
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Correlates and consequences of atrial fibrillation in a prospective study of 25 000 participants in the China Kadoorie Biobank by Turnbull, I, Camm, CF, Halsey, J, Du, H, Bennett, DA, Chen, Y, Yu, C, Sun, D, Liu, X, Li, L, Chen, Z, Clarke, R, China Kadoorie Biobank Study Group
Published 2024Journal article -
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Self-rated health status and risk of ischemic heart disease in the China Kadoorie Biobank study: a population based cohort study by Dong, W, Pan, X, Yu, C, Lv, J, Yu, G, Bian, Z, Yang, L, Chen, Y, Wu, T, Chen, Z, Pan, A, Li, L, on behalf of the China Kadoorie Biobank Collaborative Group
Published 2017Journal article -
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Study on genetic structure differences and adjustment strategies in different areas of China by Zhu, M, Lyu, J, Yu, C, Jin, G, Guo, Y, Bian, Z, Robin, W, Millwood, I, Chen, Z, Shen, H, Hu, Z, Li, L, China Kadoorie Biobank Collaborative Group
Published 2019Journal article -
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