Chromosomal context and epigenetic mechanisms control the efficacy of genome editing by rare-cutting designer endonucleases ανά Daboussi, F, Zaslavskiy, M, Poirot, L, Loperfido, M, Gouble, A, Guyot, V, Leduc, S, Galetto, R, Grizot, S, Oficjalska, D, Perez, C, Delacote, F, Dupuy, A, Chion-Sotinel, I, Le Clerre, D, Lebuhotel, C, Danos, O, Lemaire, F, Oussedik, K, Cedrone, F, Epinat, J, Smith, J, Yanez-Munoz, R, Dickson, G, Popplewell, L