Disrupting the LC3 Interaction Region (LIR) Binding of Selective Autophagy Receptors Sensitizes AML Cell Lines to Cytarabine by Mateusz Putyrski, Mateusz Putyrski, Olesya Vakhrusheva, Florian Bonn, Suchithra Guntur, Andrew Vorobyov, Christian Brandts, Christian Brandts, Christian Brandts, Ivan Dikic, Ivan Dikic, Andreas Ernst, Andreas Ernst

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Blast vacuolization in AML patients indicates adverse-risk AML and is associated with impaired survival after intensive induction chemotherapy. by Olivier Ballo, Jan Stratmann, Hubert Serve, Björn Steffen, Fabian Finkelmeier, Christian Brandts

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Targeted Therapies and Immune-Checkpoint Inhibition in Head and Neck Squamous Cell Carcinoma: Where Do We Stand Today and Where to Go? by Jens von der Grün, Franz Rödel, Christian Brandts, Emmanouil Fokas, Matthias Guckenberger, Claus Rödel, Panagiotis Balermpas

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Colonization with multidrug resistant organisms determines the clinical course of patients with acute myeloid leukemia undergoing intensive induction chemotherapy. by Olivier Ballo, Ikram Tarazzit, Jan Stratmann, Claudia Reinheimer, Michael Hogardt, Thomas A Wichelhaus, Volkhard Kempf, Hubert Serve, Fabian Finkelmeier, Christian Brandts

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SOCS1 function in BCR-ABL mediated myeloproliferative disease is dependent on the cytokine environment. by Özlem Demirel, Olivier Balló, Pavankumar N G Reddy, Olesya Vakhrusheva, Jing Zhang, Astrid Eichler, Ramona Fernandes, Susanne Badura, Hubert Serve, Christian Brandts

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P1319: TREATMENT WITH MIDOSTAURIN AND OTHER FLT3 TARGETING INHIBITORS IS ASSOCIATED WITH AN INCREASED RISK OF CARDIOVASCULAR ADVERSE EVENTS IN PATIENTS WITH FLT3 MUTATED AML WHO UN... by Anjali Cremer, Julius C. Enssle, Saskia Pfaff, Khouloud Kouidri, Fabian Lang, Christian Brandts, Andreas Zeiher, Sebastian Cremer, Björn Steffen, Hubert Serve, Gesine Bug

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Hemolysis is associated with low reticulocyte production index and predicts blood transfusion in severe malarial anemia. by Rolf Fendel, Christian Brandts, Annika Rudat, Andrea Kreidenweiss, Claudia Steur, Iris Appelmann, Bettina Ruehe, Paul Schröder, Wolfgang E Berdel, Peter G Kremsner, Benjamin Mordmüller

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P447: DECIPHERING THE MITOPHAGY RECEPTOR NETWORK IDENTIFIES A CRUCIAL ROLE FOR OPTINEURIN IN ACUTE MYELOID LEUKEMIA by Laura Meyer, Sebastian Koschade, Jonas Vischedyk, Marlyn Thölken, Andrea Gubas, Martin Wegner, Marion Basoglu, Stefan Knapp, Manuel Kaulich, Stefan Eimer, Shabnam Shaid, Christian Brandts

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Re-irradiation with concurrent and maintenance nivolumab in locally recurrent and inoperable squamous cell carcinoma of the head and neck: A single-center cohort study by Alev Altay-Langguth, Panagiotis Balermpas, Christian Brandts, Sven Balster, Shahram Ghanaati, Ria Winkelmann, Iris Burck, Franz Rödel, Daniel Martin, Claus Rödel, Jens von der Grün

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FLT3 mutations in early T-cell precursor ALL characterize a stem cell like leukemia and imply the clinical use of tyrosine kinase inhibitors. by Martin Neumann, Ebru Coskun, Lars Fransecky, Liliana H Mochmann, Isabelle Bartram, Nasrin Farhadi Sartangi, Sandra Heesch, Nicola Gökbuget, Stefan Schwartz, Christian Brandts, Cornelia Schlee, Rainer Haas, Ulrich Dührsen, Martin Griesshammer, Hartmut Döhner, Gerhard Ehninger, Thomas Burmeister, Olga Blau, Eckhard Thiel, Dieter Hoelzer, Wolf-Karsten Hofmann, Claudia D Baldus

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Defective homologous recombination DNA repair as therapeutic target in advanced chordoma by Stefan Gröschel, Daniel Hübschmann, Francesco Raimondi, Peter Horak, Gregor Warsow, Martina Fröhlich, Barbara Klink, Laura Gieldon, Barbara Hutter, Kortine Kleinheinz, David Bonekamp, Oliver Marschal, Priya Chudasama, Jagoda Mika, Marie Groth, Sebastian Uhrig, Stephen Krämer, Christoph Heining, Christoph E. Heilig, Daniela Richter, Eva Reisinger, Katrin Pfütze, Roland Eils, Stephan Wolf, Christof von Kalle, Christian Brandts, Claudia Scholl, Wilko Weichert, Stephan Richter, Sebastian Bauer, Roland Penzel, Evelin Schröck, Albrecht Stenzinger, Richard F. Schlenk, Benedikt Brors, Robert B. Russell, Hanno Glimm, Matthias Schlesner, Stefan Fröhling

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Comparative proteomics reveals a diagnostic signature for pulmonary head‐and‐neck cancer metastasis by Hanibal Bohnenberger, Lars Kaderali, Philipp Ströbel, Diego Yepes, Uwe Plessmann, Neekesh V Dharia, Sha Yao, Carina Heydt, Sabine Merkelbach‐Bruse, Alexander Emmert, Jonatan Hoffmann, Julius Bodemeyer, Kirsten Reuter‐Jessen, Anna‐Maria Lois, Leif Hendrik Dröge, Philipp Baumeister, Christoph Walz, Lorenz Biggemann, Roland Walter, Björn Häupl, Federico Comoglio, Kuan‐Ting Pan, Sebastian Scheich, Christof Lenz, Stefan Küffer, Felix Bremmer, Julia Kitz, Maren Sitte, Tim Beißbarth, Marc Hinterthaner, Martin Sebastian, Joachim Lotz, Hans‐Ulrich Schildhaus, Hendrik Wolff, Bernhard C Danner, Christian Brandts, Reinhard Büttner, Martin Canis, Kimberly Stegmaier, Hubert Serve, Henning Urlaub, Thomas Oellerich

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