Gene mutations do not operate in a vacuum: the increasing importance of epigenetics in juvenile myelomonocytic leukemia by Christian Flotho

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Induced Pluripotent Stem Cells to Model Juvenile Myelomonocytic Leukemia: New Perspectives for Preclinical Research by Zeinab Wehbe, Foued Ghanjati, Christian Flotho

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Current Treatment of Juvenile Myelomonocytic Leukemia by Christina Mayerhofer, Charlotte M. Niemeyer, Christian Flotho

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The epigenetics of breast cancer – Opportunities for diagnostics, risk stratification and therapy by Rieke Schröder, Anna-Lena Illert, Thalia Erbes, Christian Flotho, Michael Lübbert, Jesús Duque-Afonso

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P1000: JUVENILE MYELOMONOCYTIC LEUKEMIA (JMML) INHIBITS T CELL PROLIFERATION VIA THE ECTONUCLEOTIDASE CD39 AND THE PURINERGIC NETWORK by Jovana Rajak, Naile Koleci, Andreea Mesesan, Christian Flotho, Charlotte Niemeyer, Bertram Bengsch, Miriam Erlacher

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THE INTERFACE OF EPIGENETICS AND ENERGY METABOLISM IN JUVENILE MYELOMONOCYTIC LEUKEMIA by Zoé Wehbe, Ruba Hammad, Toni Cathomen, Sheila Bohler, Jovana Rajak, Miriam Erlacher, Foued Ghanjati, Charlotte Niemeyer, Christian Flotho

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Epigenetic dysregulation of the erythropoietic transcription factor KLF1 and the β-like globin locus in juvenile myelomonocytic leukemia by Silvia Fluhr, Christopher Felix Krombholz, Angelina Meier, Thomas Epting, Oliver Mücke, Christoph Plass, Charlotte M. Niemeyer, Christian Flotho

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ILLUSTRATION OF CLONAL ARCHITECTURE IN JUVENILE MYELOMONOCYTIC LEUKEMIA BY TARGETED SINGLE-CELL DNA SEQUENCING by Foued Ghanjati, Miriam Erlacher, Dirk Lebrecht, Peter Nöllke, Franco Locatelli, European Working Group Of Myelodysplastic Syndromes In Childhood, Charlotte Niemeyer, Christian Flotho

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IDENTIFICATION OF HIGH-RISK JMML BY BMP4 BISULFITE NEXT-GENERATION SEQUENCING by Foued Ghanjati, Annika Heck, Dirk Lebrecht, Peter Nöllke, Zoé Wehbe, Felicia Andresen, Natalia Rotari, Maximilian Schönung, Daniel Lipka, Miriam Erlacher, European Working Group Of Myelodysplastic Syndromes In Childhood, Charlotte Niemeyer, Christian Flotho

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Genome-wide DNA methylation is predictive of outcome in juvenile myelomonocytic leukemia by Elliot Stieglitz, Tali Mazor, Adam B. Olshen, Huimin Geng, Laura C. Gelston, Jon Akutagawa, Daniel B. Lipka, Christoph Plass, Christian Flotho, Farid F. Chehab, Benjamin S. Braun, Joseph F. Costello, Mignon L. Loh

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Abnormal B-Cell Maturation and Increased Transitional B Cells in CBL Syndrome by Francesco Saettini, Tiziana Angela Coliva, Francesca Vendemini, Marta Galbiati, Cristina Bugarin, Riccardo Masetti, Daniele Moratto, Marco Chiarini, Fabiola Guerra, Fabiola Guerra, Maria Iascone, Raffaele Badolato, Giovanni Cazzaniga, Charlotte Niemeyer, Christian Flotho, Andrea Biondi

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Epigenetic Profiling of <i>PTPN11</i> Mutant JMML Hematopoietic Stem and Progenitor Cells Reveals an Aberrant Histone Landscape by Roshani Sinha, Mai Dvorak, Ananthakrishnan Ganesan, Larry Kalesinskas, Charlotte M. Niemeyer, Christian Flotho, Kathleen M. Sakamoto, Norman Lacayo, Rachana Vinay Patil, Rhonda Perriman, Alma-Martina Cepika, Yunying Lucy Liu, Alex Kuo, Paul J. Utz, Purvesh Khatri, Alice Bertaina

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Long non-coding RNAs as novel therapeutic targets in juvenile myelomonocytic leukemia by Mattias Hofmans, Tim Lammens, Barbara Depreter, Ying Wu, Miriam Erlacher, Aurélie Caye, Hélène Cavé, Christian Flotho, Valerie de Haas, Charlotte M. Niemeyer, Jan Stary, Filip Van Nieuwerburgh, Dieter Deforce, Wouter Van Loocke, Pieter Van Vlierberghe, Jan Philippé, Barbara De Moerloose

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Hypersensitivity Reactions to Native E. coli L-asparaginase in Children With Acute Lymphoblastic Leukemia Treated in Trial ALL-BFM 2000: Impact of Treatment Schedule and Type of Gl... by Anja Möricke, Carmelo Rizzari, Julia Alten, Andishe Attarbaschi, Rita Beier, Andrea Biondi, Birgit Burkhardt, Nicole Bodmer, Joachim Boos, Gunnar Cario, Valentino Conter, Christian Flotho, Andreas Kulozik, Claudia Lanvers-Kaminsky, Georg Mann, Felix Niggli, Daniela Silvestri, Arend von Stackelberg, Martin Stanulla, Maria-Grazia Valsecchi, Martin Schrappe, Martin Zimmermann

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CircRNAs Dysregulated in Juvenile Myelomonocytic Leukemia: CircMCTP1 Stands Out by Anna Dal Molin, Mattias Hofmans, Mattias Hofmans, Enrico Gaffo, Alessia Buratin, Alessia Buratin, Hélène Cavé, Hélène Cavé, Christian Flotho, Valerie de Haas, Valerie de Haas, Charlotte M. Niemeyer, Jan Stary, Pieter Van Vlierberghe, Pieter Van Vlierberghe, Jan Philippé, Jan Philippé, Barbara De Moerloose, Barbara De Moerloose, Geertruij te Kronnie, Silvia Bresolin, Silvia Bresolin, Tim Lammens, Tim Lammens, Stefania Bortoluzzi, Stefania Bortoluzzi

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ONCO-FETAL REPROGRAMMING DRIVES HIGH-RISK JUVENILE MYELOMONOCYTIC LEUKEMIA, WHICH CAN BE TARGETED BY ANTI-CD52 TREATMENT by Mark Hartmann, Maximilian Schönung, Jovana Rajak, Joschka Hey, Valentin Maurer, Ling Hai, Sina Staeble, Jens Langstein, Katharina Bauer, Mariam Hakobyan, Laura Jardine, Sheila Bohler, Dominik Vonficht, Abdul-Habib Maag, Dirk Lebrecht, Katrin M. Bernt, Roland Roelz, Tobias Boch, Eleonora Khabirova, Pavlo Lutsik, Simon Haas, Muzlifah Haniffa, Sam Behjati, Jan-Philipp Mallm, Christian Buske, Michael D. Milsom, Stefan Fröhling, Marc-Jan Bonder, Charlotte Niemeyer, Christian Flotho, Christoph Plass, Miriam Erlacher, Matthias Schlesner, Daniel B. Lipka

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S206: ONCO-FETAL REPROGRAMMING DRIVES HIGH-RISK JUVENILE MYELOMONOCYTIC LEUKEMIA, WHICH CAN BE TARGETED BY ANTI-CD52 TREATMENT by Mark Hartmann, Maximilian Schönung, Jovana Rajak, Joschka Hey, Valentin Maurer, Ling Hai, Sina Staeble, Jens Langstein, Katharina Bauer, Mariam Hakobyan, Laura Jardine, Sheila Bohler, Dominik Vonficht, Abdul-Habib Maag, Dirk Lebrecht, Kathrin Bernt, Roland Rölz, Tobias Boch, Eleonora Khabirova, Pavlo Lutsik, Simon Haas, Muzlifah Haniffa, Sam Behjati, Jan-Philipp Mallm, Christian Buske, Michael Milsom, Stefan Fröhling, Marc-Jan Bonder, Christoph Plass, Charlotte Niemeyer, Christian Flotho, Miriam Erlacher, Matthias Schlesner, Daniel B. Lipka

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RAS-pathway mutation patterns define epigenetic subclasses in juvenile myelomonocytic leukemia by Daniel B. Lipka, Tania Witte, Reka Toth, Jing Yang, Manuel Wiesenfarth, Peter Nöllke, Alexandra Fischer, David Brocks, Zuguang Gu, Jeongbin Park, Brigitte Strahm, Marcin Wlodarski, Ayami Yoshimi, Rainer Claus, Michael Lübbert, Hauke Busch, Melanie Boerries, Mark Hartmann, Maximilian Schönung, Umut Kilik, Jens Langstein, Justyna A. Wierzbinska, Caroline Pabst, Swati Garg, Albert Catalá, Barbara De Moerloose, Michael Dworzak, Henrik Hasle, Franco Locatelli, Riccardo Masetti, Markus Schmugge, Owen Smith, Jan Stary, Marek Ussowicz, Marry M. van den Heuvel-Eibrink, Yassen Assenov, Matthias Schlesner, Charlotte Niemeyer, Christian Flotho, Christoph Plass

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