Validation of the 30-Year Framingham Risk Score in a German Population-Based Cohort by Susanne Rospleszcz, Fabian Starnecker, Birgit Linkohr, Moritz von Scheidt, Christian Gieger, Heribert Schunkert, Annette Peters

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A polygenic and family risk score are both independently associated with risk of type 2 diabetes in a population-based study by Elena Duschek, Lukas Forer, Sebastian Schönherr, Christian Gieger, Annette Peters, Florian Kronenberg, Harald Grallert, Claudia Lamina

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Smoking-Induced DNA Hydroxymethylation Signature Is Less Pronounced than True DNA Methylation: The Population-Based KORA Fit Cohort by Liye Lai, Pamela R. Matías-García, Anja Kretschmer, Christian Gieger, Rory Wilson, Jakob Linseisen, Annette Peters, Melanie Waldenberger

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Association of plasma proteomics with mortality in individuals with and without type 2 diabetes: Results from two population-based KORA cohort studies by Hong Luo, Agnese Petrera, Stefanie M. Hauck, Wolfgang Rathmann, Christian Herder, Christian Gieger, Annika Hoyer, Annette Peters, Barbara Thorand

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Are Epigenetic Factors Implicated in Chronic Widespread Pain? by Andrea Burri, Zoya Marinova, Mark D Robinson, Brigitte Kühnel, Melanie Waldenberger, Simone Wahl, Sonja Kunze, Christian Gieger, Gregory Livshits, Frances Williams

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Impact of long-term storage and freeze-thawing on eight circulating microRNAs in plasma samples. by Pamela R Matias-Garcia, Rory Wilson, Veronika Mussack, Eva Reischl, Melanie Waldenberger, Christian Gieger, Gabriele Anton, Annette Peters, Andrea Kuehn-Steven

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Detecting heritable phenotypes without a model using fast permutation testing for heritability and set-tests by Regev Schweiger, Eyal Fisher, Omer Weissbrod, Elior Rahmani, Martina Müller-Nurasyid, Sonja Kunze, Christian Gieger, Melanie Waldenberger, Saharon Rosset, Eran Halperin

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The dynamics of smoking-related disturbed methylation: a two time-point study of methylation change in smokers, non-smokers and former smokers by Rory Wilson, Simone Wahl, Liliane Pfeiffer, Cavin K. Ward-Caviness, Sonja Kunze, Anja Kretschmer, Eva Reischl, Annette Peters, Christian Gieger, Melanie Waldenberger

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The kringle IV type 2 domain variant 4925G>A causes the elusive association signal of the LPA pentanucleotide repeat by Rebecca Grüneis, Hansi Weissensteiner, Claudia Lamina, Sebastian Schönherr, Lukas Forer, Silvia Di Maio, Gertraud Streiter, Annette Peters, Christian Gieger, Florian Kronenberg, Stefan Coassin

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Metabolic Signatures Elucidate the Effect of Body Mass Index on Type 2 Diabetes by Qiuling Dong, Sidra Sidra, Christian Gieger, Rui Wang-Sattler, Wolfgang Rathmann, Cornelia Prehn, Jerzy Adamski, Wolfgang Koenig, Annette Peters, Harald Grallert, Sapna Sharma

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A systematic evaluation of short tandem repeats in lipid candidate genes: riding on the SNP-wave. by Claudia Lamina, Margot Haun, Stefan Coassin, Anita Kloss-Brandstätter, Christian Gieger, Annette Peters, Harald Grallert, Konstantin Strauch, Thomas Meitinger, Lyudmyla Kedenko, Bernhard Paulweber, Florian Kronenberg

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Gene set of nuclear-encoded mitochondrial regulators is enriched for common inherited variation in obesity. by Nadja Knoll, Ivonne Jarick, Anna-Lena Volckmar, Martin Klingenspor, Thomas Illig, Harald Grallert, Christian Gieger, Heinz-Erich Wichmann, Annette Peters, Johannes Hebebrand, André Scherag, Anke Hinney

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Tobacco smoking leads to extensive genome-wide changes in DNA methylation. by Sonja Zeilinger, Brigitte Kühnel, Norman Klopp, Hansjörg Baurecht, Anja Kleinschmidt, Christian Gieger, Stephan Weidinger, Eva Lattka, Jerzy Adamski, Annette Peters, Konstantin Strauch, Melanie Waldenberger, Thomas Illig

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Revealing the role of the human blood plasma proteome in obesity using genetic drivers by Shaza B. Zaghlool, Sapna Sharma, Megan Molnar, Pamela R. Matías-García, Mohamed A. Elhadad, Melanie Waldenberger, Annette Peters, Wolfgang Rathmann, Johannes Graumann, Christian Gieger, Harald Grallert, Karsten Suhre

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Genetics meets metabolomics: a genome-wide association study of metabolite profiles in human serum. by Christian Gieger, Ludwig Geistlinger, Elisabeth Altmaier, Martin Hrabé de Angelis, Florian Kronenberg, Thomas Meitinger, Hans-Werner Mewes, H-Erich Wichmann, Klaus M Weinberger, Jerzy Adamski, Thomas Illig, Karsten Suhre

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Analyzing longitudinal trait trajectories using GWAS identifies genetic variants for kidney function decline by Simon Wiegrebe, Mathias Gorski, Janina M. Herold, Klaus J. Stark, Barbara Thorand, Christian Gieger, Carsten A. Böger, Johannes Schödel, Florian Hartig, Han Chen, Thomas W. Winkler, Helmut Küchenhoff, Iris M. Heid

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The Human Blood Metabolome-Transcriptome Interface. by Jörg Bartel, Jan Krumsiek, Katharina Schramm, Jerzy Adamski, Christian Gieger, Christian Herder, Maren Carstensen, Annette Peters, Wolfgang Rathmann, Michael Roden, Konstantin Strauch, Karsten Suhre, Gabi Kastenmüller, Holger Prokisch, Fabian J Theis

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Alterations in Lipid and Inositol Metabolisms in Two Dopaminergic Disorders. by Eva C Schulte, Elisabeth Altmaier, Hannah S Berger, Kieu Trinh Do, Gabi Kastenmüller, Simone Wahl, Jerzy Adamski, Annette Peters, Jan Krumsiek, Karsten Suhre, Bernhard Haslinger, Andres Ceballos-Baumann, Christian Gieger, Juliane Winkelmann

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Prediction of Myocardial Infarction Using a Combined Generative Adversarial Network Model and Feature-Enhanced Loss Function by Shixiang Yu, Siyu Han, Mengya Shi, Makoto Harada, Jianhong Ge, Xuening Li, Xiang Cai, Margit Heier, Gabi Karstenmüller, Karsten Suhre, Christian Gieger, Wolfgang Koenig, Wolfgang Rathmann, Annette Peters, Rui Wang-Sattler

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Phenotypic and genome-wide studies on dicarbonyls: major associations to glomerular filtration rate and gamma-glutamyltransferase activityResearch in context by Philip Harrer, Julica Inderhees, Chen Zhao, Barbara Schormair, Erik Tilch, Christian Gieger, Annette Peters, Olaf Jöhren, Thomas Fleming, Peter P. Nawroth, Klaus Berger, Marco Hermesdorf, Juliane Winkelmann, Markus Schwaninger, Konrad Oexle

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