Microglia Are Essential to Protective Antiviral Immunity: Lessons From Mouse Models of Viral Encephalitis by Catherine F. Hatton, Christopher J. A. Duncan, Christopher J. A. Duncan

Get full text

Viral Determinants of HIV-1 Macrophage Tropism by Christopher J. A. Duncan, Quentin J. Sattentau

Get full text

Life-Threatening Influenza, Hemophagocytic Lymphohistiocytosis and Probable Vaccine-Strain Varicella in a Novel Case of Homozygous STAT2 Deficiency by Bishara J. Freij, Bishara J. Freij, Aidan T. Hanrath, Rui Chen, Sophie Hambleton, Sophie Hambleton, Christopher J. A. Duncan, Christopher J. A. Duncan

Get full text

Type I interferon receptor (IFNAR2) deficiency reveals Zika virus cytopathicity in human macrophages and microglia by Aidan T. Hanrath, Aidan T. Hanrath, Catherine F. Hatton, Catherine F. Hatton, Florian Gothe, Cathy Browne, Jane Vowles, Peter Leary, Simon J. Cockell, Simon J. Cockell, Sally A. Cowley, William S. James, Sophie Hambleton, Sophie Hambleton, Christopher J. A. Duncan, Christopher J. A. Duncan, Christopher J. A. Duncan

Get full text

Acute kidney injury (AKI) associated with intravenous aciclovir in adults: Incidence and risk factors in clinical practice by Lucy Ryan, Andrew Heed, Jonathan Foster, Manoj Valappil, Matthias L. Schmid, Christopher J.A. Duncan

Get full text

The trajectory of COVID-19 cardiopulmonary disease: insights from an autopsy study of community-based, pre-hospital deaths by Luke Milross, Joaquim Majo, Julian Pulle, Sam Hoggard, Nigel Cooper, Bethany Hunter, Christopher J.A. Duncan, Andrew Filby, Andrew J. Fisher

Get full text

Persistent SARS-CoV-2 infection in patients with secondary antibody deficiency: successful clearance following combination casirivimab and imdevimab (REGN-COV2) monoclonal antibody... by Yusri Taha, Hayley Wardle, Adam B. Evans, Ewan R. Hunter, Helen Marr, Wendy Osborne, Matthew Bashton, Darren Smith, Shirelle Burton-Fanning, Matthias L. Schmid, Christopher J. A. Duncan

Get full text

Pyogenic Spondylodiscitis: Risk Factors for Adverse Clinical Outcome in Routine Clinical Practice by John D. Widdrington, Ingrid Emmerson, Milo Cullinan, Manjusha Narayanan, Eleanor Klejnow, Alistair Watson, Edmund L. C. Ong, Matthias L. Schmid, D. Ashley Price, Ulrich Schwab, Christopher J. A. Duncan

Get full text

COVID-19 vaccines are effective at preventing symptomatic and severe infection among healthcare workers: A clinical review by Oliver Galgut, Fiona Ashford, Alexandra Deeks, Andeep Ghataure, Mimia Islam, Tanvir Sambhi, Yiu Wayn Ker, Christopher J.A. Duncan, Thushan I. de Silva, Susan Hopkins, Victoria Hall, Paul Klenerman, Susanna Dunachie, Alex Richter

Get full text

Comparison of clinical and parasitological data from controlled human malaria infection trials. by Meta Roestenberg, Geraldine A O'Hara, Christopher J A Duncan, Judith E Epstein, Nick J Edwards, Anja Scholzen, André J A M van der Ven, Cornelus C Hermsen, Adrian V S Hill, Robert W Sauerwein

Get full text

Clinical frailty, and not features of acute infection, is associated with late mortality in COVID‐19: a retrospective cohort study by Nikolaos I. Vlachogiannis, Kenneth F. Baker, Georgios Georgiopoulos, Charalampos Lazaridis, Ina Schim van der Loeff, Aidan T. Hanrath, Kateryna Sopova, Simon Tual‐Chalot, Aikaterini Gatsiou, Ioakim Spyridopoulos, Kimon Stamatelopoulos, Christopher J.A. Duncan, Konstantinos Stellos

Get full text

mRNA vaccination drives differential mucosal neutralizing antibody profiles in naïve and SARS-CoV-2 previously-infected individuals by Stephanie Longet, Stephanie Longet, Alexander Hargreaves, Alexander Hargreaves, Saoirse Healy, Saoirse Healy, Rebecca Brown, Hailey R. Hornsby, Naomi Meardon, Tom Tipton, Tom Tipton, Eleanor Barnes, Eleanor Barnes, Susanna Dunachie, Susanna Dunachie, Susanna Dunachie, Susanna Dunachie, Christopher J. A. Duncan, Christopher J. A. Duncan, Paul Klenerman, Paul Klenerman, Paul Klenerman, Paul Klenerman, Alex Richter, Alex Richter, Lance Turtle, Lance Turtle, Thushan I. de Silva, Thushan I. de Silva, Miles W. Carroll, Miles W. Carroll

Get full text

SARS-CoV-2 Testing of 11,884 Healthcare Workers at an Acute NHS Hospital Trust in England: A Retrospective Analysis by Aidan T. Hanrath, Ina Schim van der Loeff, Dennis W. Lendrem, Dennis W. Lendrem, Kenneth F. Baker, Kenneth F. Baker, David A. Price, Peter McDowall, Kiera McDowall, Susan Cook, Peter Towns, Ulrich Schwab, Adam Evans, Jill Dixon, Jennifer Collins, Shirelle Burton-Fanning, David Saunders, Jayne Harwood, Julie Samuel, Matthias L. Schmid, Lucia Pareja-Cebrian, Ewan Hunter, Elizabeth Murphy, Yusri Taha, Brendan A. I. Payne, Brendan A. I. Payne, Christopher J. A. Duncan, Christopher J. A. Duncan

Get full text

Distinct lung cell signatures define the temporal evolution of diffuse alveolar damage in fatal COVID-19Research in context by Luke Milross, Bethany Hunter, David McDonald, George Merces, Amanda Thomson, Catharien M.U. Hilkens, John Wills, Paul Rees, Kasim Jiwa, Nigel Cooper, Joaquim Majo, Helen Ashwin, Christopher J.A. Duncan, Paul M. Kaye, Omer Ali Bayraktar, Andrew Filby, Andrew J. Fisher

Get full text

Assessment of humoral immune responses to blood-stage malaria antigens following ChAd63-MVA immunization, controlled human malaria infection and natural exposure. by Sumi Biswas, Prateek Choudhary, Sean C Elias, Kazutoyo Miura, Kathryn H Milne, Simone C de Cassan, Katharine A Collins, Fenella D Halstead, Carly M Bliss, Katie J Ewer, Faith H Osier, Susanne H Hodgson, Christopher J A Duncan, Geraldine A O'Hara, Carole A Long, Adrian V S Hill, Simon J Draper

Get full text

Estimated pulse wave velocity improves risk stratification for all-cause mortality in patients with COVID-19 by Kimon Stamatelopoulos, Georgios Georgiopoulos, Kenneth F. Baker, Giusy Tiseo, Dimitrios Delialis, Charalampos Lazaridis, Greta Barbieri, Stefano Masi, Nikolaos I. Vlachogiannis, Kateryna Sopova, Alessandro Mengozzi, Lorenzo Ghiadoni, Ina Schim van der Loeff, Aidan T. Hanrath, Bajram Ajdini, Charalambos Vlachopoulos, Meletios A. Dimopoulos, Christopher J. A. Duncan, Marco Falcone, Konstantinos Stellos, the Pisa COVID-19 Research Group, Newcastle COVID-19 Research Group

Get full text

CD4+ and CD8+ T cells and antibodies are associated with protection against Delta vaccine breakthrough infection: a nested case-control study within the PITCH study by Isabel Neale, Mohammad Ali, Barbara Kronsteiner, Stephanie Longet, Priyanka Abraham, Alexandra S. Deeks, Anthony Brown, Shona C. Moore, Lizzie Stafford, Susan L. Dobson, Megan Plowright, Thomas A. H. Newman, Mary Y. Wu, Edward J. Carr, Rupert Beale, Ashley D. Otter, Susan Hopkins, Victoria Hall, Adriana Tomic, Rebecca P. Payne, Eleanor Barnes, Alex Richter, Christopher J. A. Duncan, Lance Turtle, Thushan I. de Silva, Miles Carroll, Teresa Lambe, Paul Klenerman, Susanna Dunachie

Get full text

COVID-19 Management in a UK NHS Foundation Trust with a High Consequence Infectious Diseases Centre: A Retrospective Analysis by Kenneth F. Baker, Aidan T. Hanrath, Ina Schim van der Loeff, Su Ann Tee, Richard Capstick, Gabriella Marchitelli, Ang Li, Andrew Barr, Alsafi Eid, Sajeel Ahmed, Dalvir Bajwa, Omer Mohammed, Neil Alderson, Clare Lendrem, Dennis W. Lendrem, COVID-19 Control Group, COVID-19 Clinical Group, Lucia Pareja-Cebrian, Andrew Welch, Joanne Field, Brendan A. I. Payne, Yusri Taha, David A. Price, Christopher Gibbins, Matthias L. Schmid, Ewan Hunter, Christopher J. A. Duncan

Get full text

Impact of vaccination on hospitalization and mortality from COVID-19 in patients with primary and secondary immunodeficiency: The United Kingdom experience by Adrian M. Shields, Adrian M. Shields, Susan Tadros, Adam Al-Hakim, Jeremy M. Nell, Me Me Nay Lin, Michele Chan, Sarah Goddard, John Dempster, Magdalena Dziadzio, Smita Y. Patel, Smita Y. Patel, Shuayb Elkalifa, Aarnoud Huissoon, Christopher J. A. Duncan, Archana Herwadkar, Sujoy Khan, Claire Bethune, Suzanne Elcombe, James Thaventhiran, Paul Klenerman, David M. Lowe, David M. Lowe, Sinisa Savic, Siobhan O. Burns, Siobhan O. Burns, Alex G. Richter, Alex G. Richter

Get full text

Impact on malaria parasite multiplication rates in infected volunteers of the protein-in-adjuvant vaccine AMA1-C1/Alhydrogel+CPG 7909. by Christopher J A Duncan, Susanne H Sheehy, Katie J Ewer, Alexander D Douglas, Katharine A Collins, Fenella D Halstead, Sean C Elias, Patrick J Lillie, Kelly Rausch, Joan Aebig, Kazutoyo Miura, Nick J Edwards, Ian D Poulton, Angela Hunt-Cooke, David W Porter, Fiona M Thompson, Ros Rowland, Simon J Draper, Sarah C Gilbert, Michael P Fay, Carole A Long, Daming Zhu, Yimin Wu, Laura B Martin, Charles F Anderson, Alison M Lawrie, Adrian V S Hill, Ruth D Ellis

Get full text