Cause or effect? Interpreting emerging evidence for dysbiosis in systemic sclerosis by Christopher P. Denton, Charles Murray

Get full text

News and failures from recent treatment trials in systemic sclerosis by Christopher P. Denton, Philip Yee, Voon H. Ong

Get full text

Recent developments in connective tissue disease associated pulmonary arterial hypertension by Stefano Rodolfi, Voon H. Ong, Christopher P. Denton

Get full text

Systemic Sclerosis by Michael Hughes, Yannick Allanore, Christopher P. Denton, Marco Matucci-Cerinic

Get full text

Impact of Scleroderma‐Associated Autoantibodies on Clinical Outcome Assessments: Post Hoc Analysis From a Randomised, Double‐blind, Placebo‐controlled, Phase 3 Trial of Tocilizumab... by Basmah Al Dulaijan, Suiyuan Huang, Celia J. F. Lin, Christopher P. Denton, Dinesh Khanna

Get full text

Rac inhibition reverses the phenotype of fibrotic fibroblasts. by Shi-wen Xu, Shangxi Liu, Mark Eastwood, Sonali Sonnylal, Christopher P Denton, David J Abraham, Andrew Leask

Get full text

Reduced exercise capacity in patients with systemic sclerosis is associated with lower peak tissue oxygen extraction: a cardiovascular magnetic resonance-augmented cardiopulmonary... by James T. Brown, Tushar Kotecha, Jennifer A. Steeden, Marianna Fontana, Christopher P. Denton, J. Gerry Coghlan, Daniel S. Knight, Vivek Muthurangu

Get full text

Combinations of scleroderma hallmark autoantibodies associate with distinct clinical phenotypes by Kristina E. N. Clark, Corrado Campochiaro, Lauren V. Host, Alper Sari, Jennifer Harvey, Christopher P. Denton, Voon H. Ong

Get full text

Dysregulated B cell function and disease pathogenesis in systemic sclerosis by Claire F. Beesley, Nina R. Goldman, Taher E. Taher, Christopher P. Denton, David J. Abraham, Rizgar A. Mageed, Voon H. Ong

Get full text

Single-Cell Analysis of ADSC Interactions with Fibroblasts and Endothelial Cells in Scleroderma Skin by Marvin L. Frommer, Benjamin J. Langridge, Laura Awad, Sara Jasionowska, Christopher P. Denton, David J. Abraham, Jeries Abu-Hanna, Peter E. M. Butler

Get full text

Lysophosphatidic acid receptor 1 inhibition: a potential treatment target for pulmonary fibrosis by Elizabeth R. Volkmann, Christopher P. Denton, Martin Kolb, Marlies S. Wijsenbeek-Lourens, Claire Emson, Krischan Hudson, Anthony J. Amatucci, Oliver Distler, Yannick Allanore, Dinesh Khanna

Get full text

Exploring Anti-Fibrotic Effects of Adipose-Derived Stem Cells: Transcriptome Analysis upon Fibrotic, Inflammatory, and Hypoxic Conditioning by Marvin L. Frommer, Benjamin J. Langridge, Alexandra Beedie, Sara Jasionowska, Laura Awad, Christopher P. Denton, David J. Abraham, Jeries Abu-Hanna, Peter E. M. Butler

Get full text

Effect of ambrisentan in patients with systemic sclerosis and mild pulmonary arterial hypertension: long-term follow-up data from EDITA study by Panagiota Xanthouli, Paul Uesbeck, Hanns-Martin Lorenz, Norbert Blank, Christina A. Eichstaedt, Satenik Harutyunova, Benjamin Egenlauf, Jerry G. Coghlan, Christopher P. Denton, Ekkehard Grünig, Nicola Benjamin

Get full text

Induction of Pro-Fibrotic CLIC4 in Dermal Fibroblasts by TGF-β/Wnt3a Is Mediated by GLI2 Upregulation by Christopher W. Wasson, Begoña Caballero-Ruiz, Justin Gillespie, Emma Derrett-Smith, Jamel Mankouri, Christopher P. Denton, Gianluca Canettieri, Natalia A. Riobo-Del Galdo, Francesco Del Galdo

Get full text

Rituximab versus cyclophosphamide for the treatment of connective tissue disease-associated interstitial lung disease (RECITAL): study protocol for a randomised controlled trial by Peter Saunders, Vicky Tsipouri, Gregory J. Keir, Deborah Ashby, Marcus D. Flather, Helen Parfrey, Daphne Babalis, Elisabetta A. Renzoni, Christopher P. Denton, Athol U. Wells, Toby M. Maher

Get full text

The pan-PPAR agonist lanifibranor reduces development of lung fibrosis and attenuates cardiorespiratory manifestations in a transgenic mouse model of systemic sclerosis by Emma Derrett-Smith, Kristina E. N. Clark, Xu Shiwen, David J. Abraham, Rachel K. Hoyles, Olivier Lacombe, Pierre Broqua, Jean Louis Junien, Irena Konstantinova, Voon H. Ong, Christopher P. Denton

Get full text

Use of Patterned Collagen Coated Slides to Study Normal and Scleroderma Lung Fibroblast Migration by Bahja Ahmed Abdi, Henry Lopez, Sarah Karrar, Elisabetta Renzoni, Athol Wells, Angela Tam, Oseme Etomi, J. Justin Hsuan, George R. Martin, Xu Shiwen, Christopher P. Denton, David Abraham, Richard Stratton

Get full text

Effect of nintedanib in patients with systemic sclerosis-associated interstitial lung disease and risk factors for rapid progression by Toby M Maher, Michael Kreuter, Vanessa Smith, Yannick Allanore, Elizabeth R Volkmann, Dinesh Khanna, Christopher P Denton, Anna-Maria Hoffmann-Vold, Shervin Assassi, Masataka Kuwana, Margarida Alves, Christian Stock, Steven Sambevski

Get full text

Zibotentan in systemic sclerosis-associated chronic kidney disease: a phase II randomised placebo-controlled trial by Edward P. Stern, Lauren V. Host, Ivy Wanjiku, K. Jane Escott, Peter S. Gilmour, Rachel Ochiel, Robert Unwin, Aine Burns, Voon H. Ong, Helen Cadiou, Aidan G. O’Keeffe, Christopher P. Denton

Get full text

Limited cutaneous systemic sclerosis skin demonstrates distinct molecular subsets separated by a cardiovascular development gene expression signature by Emma C. Derrett-Smith, Viktor Martyanov, Cecilia B. Chighizola, Pia Moinzadeh, Corrado Campochiaro, Korsa Khan, Tammara A. Wood, Pier Luigi Meroni, David J. Abraham, Voon H. Ong, Robert Lafyatis, Michael L. Whitfield, Christopher P. Denton

Get full text