Pcsk5 is required in the early cranio-cardiac mesoderm for heart development. by Szumska, D, Cioroch, M, Keeling, A, Prat, A, Seidah, NG, Bhattacharya, S

RNAi-mediated knockdown of HMG CoA reductase enhances gene expression from physiologically regulated low-density lipoprotein receptor therapeutic vectors in vivo by Hibbitt, O, Agkatsev, S, Owen, C, Cioroch, M, Seymour, L, Channon, K, Wade-Martins, R

RNAi-mediated knockdown of HMG CoA reductase enhances gene expression from physiologically regulated low-density lipoprotein receptor therapeutic vectors in vivo. by Hibbitt, O, Agkatsev, S, Owen, C, Cioroch, M, Seymour, L, Channon, K, Wade-Martins, R

Episomal non-viral gene therapy vectors slow progression of atherosclerosis in a model of familial hypercholesterolemia by Kerr, A, Tam, L, Hale, A, Cioroch, M, Douglas, G, Channon, K, Wade-Martins, R

A novel combinatorial non-viral vector to treat familial hypercholesterolaemia (FH) by Kerr, A, Tam, L, Cioroch, M, Hale, A, Douglas, G, Channon, K, Wade-Martins, R

19. Using a novel combinatorial non-viral vector and small molecules to treat familial hypercholesterolaemia (FH) by Kerr, A, Tam, L, Cioroch, M, Hale, A, Douglas, G, Mason, J, Bataille, C, Wynne, G, Russell, A, Channon, K, Wade-Martins, R

Impairment of macroautophagy in dopamine neurons has opposing effects on parkinsonian pathology and behaviour by Hunn, B, Vingill, S, Threlfell, S, Alegre-Abarrategui, J, Magdelyns, M, Deltheil, T, Bengoa-Vergniory, N, Oliver, P, Cioroch, M, Doig, N, Bannerman, D, Cragg, S, Wade-Martins, R

REST protects dopaminergic neurons from mitochondrial and α-synuclein oligomer pathology in an alpha synuclein overexpressing BAC-transgenic mouse model by Ryan, BJ, Bengoa-Vergniory, N, Williamson, M, Kirkiz, E, Roberts, R, Corda, G, Sloan, M, Saqlain, S, Cherubini, M, Poppinga, J, Bogtofte, H, Cioroch, M, Hester, S, Wade-Martins, R

Preclinical development of a vaccine against oligomeric alpha-synuclein based on virus-like particles by Doucet, M, El-Turabi, A, Zabel, F, Hunn, B, Bengoa-Vergniory, N, Cioroch, M, Ramm, M, Smith, A, Gomes, A, Cabral de Miranda, G, Wade-Martins, R, Bachmann, M

A genomic DNA reporter screen identifies squalene synthase inhibitors which act cooperatively with statins to upregulate the low-density lipoprotein receptor by Kerr, A, Tam, L, Hale, A, Cioroch, M, Douglas, G, Agkatsev, S, Hibbit, O, Mason, J, Holt-Martyn, J, Bataille, C, Wynne, G, Channon, K, Russell, A, Wade-Martins, R

Region-specific deficits in dopamine, but not norepinephrine, signaling in a novel A30P α-synuclein BAC transgenic mouse. by Taylor, T, Potgieter, D, Anwar, S, Senior, S, Janezic, S, Threlfell, S, Ryan, B, Parkkinen, L, Deltheil, T, Cioroch, M, Livieratos, A, Oliver, P, Jennings, K, Davies, K, Ansorge, O, Bannerman, D, Cragg, S, Wade-Martins, R

LRRK2 BAC transgenic rats develop progressive, L-DOPA-responsive motor impairment, and deficits in dopamine circuit function. by Sloan, M, Alegre-Abarrategui, J, Potgieter, D, Kaufmann, A, Exley, R, Deltheil, T, Threlfell, S, Connor-Robson, N, Brimblecombe, K, Wallings, R, Cioroch, M, Bannerman, D, Bolam, J, Magill, P, Cragg, S, Dodson, P, Wade-Martins, R

Deficits in dopaminergic transmission precede neuron loss and dysfunction in a new Parkinson model. by Janezic, S, Threlfell, S, Dodson, P, Dowie, M, Taylor, T, Potgieter, D, Parkkinen, L, Senior, S, Anwar, S, Ryan, B, Deltheil, T, Kosillo, P, Cioroch, M, Wagner, K, Ansorge, O, Bannerman, D, Bolam, J, Magill, P, Cragg, S, Wade-Martins, R

CLR01 protects dopaminergic neurons in vitro and in mouse models of Parkinson’s disease by Bengoa-Vergniory, N, Faggiani, E, Ramos-Gonzalez, P, Kirkiz, E, Connor-Robson, N, Brown, L, Siddique, I, Li, Z, Vingill, S, Cioroch, M, Cavaliere, F, Threlfell, S, Roberts, B, Schrader, T, Klärner, F-G, Cragg, S, Gal Bitan, Dehay, B, Matute, C, Bezard, E, Wade-Martins, R