Identification of age-dependent motor and neuropsychological behavioural abnormalities in a mouse model of Mucopolysaccharidosis Type II. by Hélène F E Gleitz, Claire O'Leary, Rebecca J Holley, Brian W Bigger

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Strategies for the Induction of Immune Tolerance to Enzyme Replacement Therapy in Mucopolysaccharidosis Type I by Arunabha Ghosh, Aiyin Liao, Claire O’Leary, Jean Mercer, Karen Tylee, Anu Goenka, Rebecca Holley, Simon A. Jones, Brian W. Bigger

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Non-myeloablative busulfan chimeric mouse models are less pro-inflammatory than head-shielded irradiation for studying immune cell interactions in brain tumours by A. Saam Youshani, Samuel Rowlston, Claire O’Leary, Gabriella Forte, Helen Parker, Aiyin Liao, Brian Telfer, Kaye Williams, Ian D. Kamaly-Asl, Brian W. Bigger

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Brain‐targeted stem cell gene therapy corrects mucopolysaccharidosis type II via multiple mechanisms by Hélène FE Gleitz, Ai Yin Liao, James R Cook, Samuel F Rowlston, Gabriella MA Forte, Zelpha D'Souza, Claire O'Leary, Rebecca J Holley, Brian W Bigger

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Value of dynamic clinical and biomarker data for mortality risk prediction in COVID-19: a multicentre retrospective cohort study by James Galea, Andrew King, Kayode Ogungbenro, Omar Pathmanaban, Andy Vail, Hiren C Patel, Carlo Berzuini, Cathal Hannan, Claire O'Leary, David Brough, Megan Wright, Sharon Hulme, Stuart Allan, Luisa Bernardinelli

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Haematopoietic stem cell gene therapy with IL‐1Ra rescues cognitive loss in mucopolysaccharidosis IIIA by Helen Parker, Stuart M Ellison, Rebecca J Holley, Claire O'Leary, Aiyin Liao, Jalal Asadi, Emily Glover, Arunabha Ghosh, Simon Jones, Fiona L Wilkinson, David Brough, Emmanuel Pinteaux, Hervé Boutin, Brian W Bigger

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Resolving pathobiological mechanisms relating to Huntington disease: Gait, balance, and involuntary movements in mice with targeted ablation of striatal D1 dopamine receptor cells by Hyun Ah. Kim, Luning Jiang, Heather Madsen, Clare L. Parish, Jim Massalas, Arthur Smardencas, Claire O'Leary, Ilse Gantois, Colm O'Tuathaigh, John L. Waddington, Michelle E. Ehrlich, Andrew J. Lawrence, John Drago

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Early defects in mucopolysaccharidosis type IIIC disrupt excitatory synaptic transmission by Camila Pará, Poulomee Bose, Luigi Bruno, Erika Freemantle, Mahsa Taherzadeh, Xuefang Pan, Chanshuai Han, Peter S. McPherson, Jean-Claude Lacaille, Éric Bonneil, Pierre Thibault, Claire O’Leary, Brian Bigger, Carlos Ramon Morales, Graziella Di Cristo, Alexey V. Pshezhetsky

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Intraparenchymal convection enhanced delivery of AAV in sheep to treat Mucopolysaccharidosis IIIC by Claire O’Leary, Gabriella Forte, Nadia L. Mitchell, Amir Saam Youshani, Adam Dyer, Martin P. Wellby, Katharina N. Russell, Samantha J. Murray, Nelly Jolinon, Simon A Jones, Kevin Stacey, Daniel M. Davis, Els Henckaerts, David N. Palmer, Ian Kamaly-Asl, Brian W. Bigger

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Study protocol: PreOperative Brain Irradiation in Glioblastoma (POBIG) – A phase I trial by Mueez Waqar, Federico Roncaroli, Ibrahim Djoukhadar, Leila Akkari, Claire O'Leary, Lauren Hewitt, Gabriella Forte, Richard Jackson, Eline Hessen, Lisa Withington, William Beasley, Jenny Richardson, Christopher Golby, Philip Whitehurst, Rovel Colaco, Matthew Bailey, Konstantina Karabatsou, Pietro I. D'Urso, Catherine McBain, David J. Coope, Gerben R. Borst

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