GWAS Reveal Targets in Vessel Wall Pathways to Treat Coronary Artery Disease by Adam W. Turner, Doris Wong, Doris Wong, Caitlin N. Dreisbach, Caitlin N. Dreisbach, Clint L. Miller, Clint L. Miller, Clint L. Miller, Clint L. Miller

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Genome-Wide Association Studies Candidate Gene to Dual Modifier of Nonalcoholic Steatohepatitis and Atherosclerosis by Clint L. Miller, PhD, Nicholas J. Leeper, MD

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PlaqView 2.0: A comprehensive web portal for cardiovascular single-cell genomics by Wei Feng Ma, Wei Feng Ma, Adam W. Turner, Christina Gancayco, Doris Wong, Doris Wong, Yipei Song, Yipei Song, Jose Verdezoto Mosquera, Jose Verdezoto Mosquera, Gaëlle Auguste, Chani J. Hodonsky, Ajay Prabhakar, H. Atakan Ekiz, Sander W. van der Laan, Clint L. Miller, Clint L. Miller, Clint L. Miller

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TCF21 and AP-1 interact through epigenetic modifications to regulate coronary artery disease gene expression by Quanyi Zhao, Robert Wirka, Trieu Nguyen, Manabu Nagao, Paul Cheng, Clint L. Miller, Juyong Brian Kim, Milos Pjanic, Thomas Quertermous

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Coronary artery disease genes SMAD3 and TCF21 promote opposing interactive genetic programs that regulate smooth muscle cell differentiation and disease risk. by Dharini Iyer, Quanyi Zhao, Robert Wirka, Ameay Naravane, Trieu Nguyen, Boxiang Liu, Manabu Nagao, Paul Cheng, Clint L Miller, Juyong Brian Kim, Milos Pjanic, Thomas Quertermous

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Gene-repressing epigenetic reader EED unexpectedly enhances cyclinD1 gene activation by Mengxue Zhang, Jing Li, Qingwei Wang, Go Urabe, Runze Tang, Yitao Huang, Jose Verdezoto Mosquera, K. Craig Kent, Bowen Wang, Clint L. Miller, Lian-Wang Guo

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TCF21 and the environmental sensor aryl-hydrocarbon receptor cooperate to activate a pro-inflammatory gene expression program in coronary artery smooth muscle cells. by Juyong Brian Kim, Milos Pjanic, Trieu Nguyen, Clint L Miller, Dharini Iyer, Boxiang Liu, Ting Wang, Olga Sazonova, Ivan Carcamo-Orive, Ljubica Perisic Matic, Lars Maegdefessel, Ulf Hedin, Thomas Quertermous

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An automatic entropy method to efficiently mask histology whole-slide images by Yipei Song, Francesco Cisternino, Joost M. Mekke, Gert J. de Borst, Dominique P. V. de Kleijn, Gerard Pasterkamp, Aryan Vink, Craig A. Glastonbury, Sander W. van der Laan, Clint L. Miller

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Coronary heart disease-associated variation in TCF21 disrupts a miR-224 binding site and miRNA-mediated regulation. by Clint L Miller, Ulrike Haas, Roxanne Diaz, Nicholas J Leeper, Ramendra K Kundu, Bhagat Patlolla, Themistocles L Assimes, Frank J Kaiser, Ljubica Perisic, Ulf Hedin, Lars Maegdefessel, Heribert Schunkert, Jeanette Erdmann, Thomas Quertermous, Georg Sczakiel

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Disease-related growth factor and embryonic signaling pathways modulate an enhancer of TCF21 expression at the 6q23.2 coronary heart disease locus. by Clint L Miller, D Ryan Anderson, Ramendra K Kundu, Azad Raiesdana, Sylvia T Nürnberg, Roxanne Diaz, Karen Cheng, Nicholas J Leeper, Chung-Hsing Chen, I-Shou Chang, Eric E Schadt, Chao Agnes Hsiung, Themistocles L Assimes, Thomas Quertermous

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Vascular smooth muscle cell dysfunction contribute to neuroinflammation and Tau hyperphosphorylation in Alzheimer disease by Jorge A. Aguilar-Pineda, Karin J. Vera-Lopez, Pallavi Shrivastava, Miguel A. Chávez-Fumagalli, Rita Nieto-Montesinos, Karla L. Alvarez-Fernandez, Luis D. Goyzueta Mamani, Gonzalo Davila Del-Carpio, Badhin Gomez-Valdez, Clint L. Miller, Rajeev Malhotra, Mark E. Lindsay, Christian L. Lino Cardenas

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Functional regulatory mechanism of smooth muscle cell-restricted LMOD1 coronary artery disease locus. by Vivek Nanda, Ting Wang, Milos Pjanic, Boxiang Liu, Trieu Nguyen, Ljubica Perisic Matic, Ulf Hedin, Simon Koplev, Lijiang Ma, Oscar Franzén, Arno Ruusalepp, Eric E Schadt, Johan L M Björkegren, Stephen B Montgomery, Michael P Snyder, Thomas Quertermous, Nicholas J Leeper, Clint L Miller

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The accumulation of erythrocytes quantified and visualized by Glycophorin C in carotid atherosclerotic plaque reflects intraplaque hemorrhage and pre-procedural neurological sympt... by Joost M. Mekke, Tim R. Sakkers, Maarten C. Verwer, Noortje A. M. van den Dungen, Yipei Song, Clint L. Miller, Aloke V. Finn, Gerard Pasterkamp, Michal Mokry, Hester M. den Ruijter, Aryan Vink, Dominique P. V. de Kleijn, Gert J. de Borst, Saskia Haitjema, Sander W. van der Laan

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Coronary Artery Disease Associated Transcription Factor TCF21 Regulates Smooth Muscle Precursor Cells That Contribute to the Fibrous Cap. by Sylvia T Nurnberg, Karen Cheng, Azad Raiesdana, Ramendra Kundu, Clint L Miller, Juyong B Kim, Komal Arora, Ivan Carcamo-Oribe, Yiqin Xiong, Nikhil Tellakula, Vivek Nanda, Nikitha Murthy, William A Boisvert, Ulf Hedin, Ljubica Perisic, Silvia Aldi, Lars Maegdefessel, Milos Pjanic, Gary K Owens, Michelle D Tallquist, Thomas Quertermous

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The HDAC9-associated risk locus promotes coronary artery disease by governing TWIST1. by Lijiang Ma, Nicole S Bryce, Adam W Turner, Antonio F Di Narzo, Karishma Rahman, Yang Xu, Raili Ermel, Katyayani Sukhavasi, Valentina d'Escamard, Nirupama Chandel, Bhargavi V'Gangula, Kathryn Wolhuter, Daniella Kadian-Dodov, Oscar Franzen, Arno Ruusalepp, Ke Hao, Clint L Miller, Johan L M Björkegren, Jason C Kovacic

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Treatment of calcific arterial disease via enhancement of autophagy using GSK343 by Christian L. Lino Cardenas, Wanlin Jiang, Lova P. Kajuluri, Kuldeep Singh, Katrina Ostrom, Rebecca Li, Francois Cherbonneau, Sophie Boerboom, Claire Birchenough, Kangsan Roh, Elizabeth L. Chou, Zarbafian Shahrooz, Christopher Nicholson, Adam L. Johnson, Sujin Lee, Fumito Ichinose, Donald B. Bloch, Sagar Nigwekar, Patrick T. Ellinor, Patricia Musolino, Mark E. Lindsay, Zhixun Dou, Clint L. Miller, Rajeev Malhotra

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Multi-ancestry genetic analysis of gene regulation in coronary arteries prioritizes disease risk loci by Chani J. Hodonsky, Adam W. Turner, Mohammad Daud Khan, Nelson B. Barrientos, Ruben Methorst, Lijiang Ma, Nicolas G. Lopez, Jose Verdezoto Mosquera, Gaëlle Auguste, Emily Farber, Wei Feng Ma, Doris Wong, Suna Onengut-Gumuscu, Maryam Kavousi, Patricia A. Peyser, Sander W. van der Laan, Nicholas J. Leeper, Jason C. Kovacic, Johan L.M. Björkegren, Clint L. Miller

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Integrative single-cell meta-analysis reveals disease-relevant vascular cell states and markers in human atherosclerosis by Jose Verdezoto Mosquera, Gaëlle Auguste, Doris Wong, Adam W. Turner, Chani J. Hodonsky, Astrid Catalina Alvarez-Yela, Yipei Song, Qi Cheng, Christian L. Lino Cardenas, Konstantinos Theofilatos, Maxime Bos, Maryam Kavousi, Patricia A. Peyser, Manuel Mayr, Jason C. Kovacic, Johan L.M. Björkegren, Rajeev Malhotra, P. Todd Stukenberg, Aloke V. Finn, Sander W. van der Laan, Chongzhi Zang, Nathan C. Sheffield, Clint L. Miller

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CD163+ macrophages restrain vascular calcification, promoting the development of high-risk plaque by Atsushi Sakamoto, Rika Kawakami, Masayuki Mori, Liang Guo, Ka Hyun Paek, Jose Verdezoto Mosquera, Anne Cornelissen, Saikat Kumar B. Ghosh, Kenji Kawai, Takao Konishi, Raquel Fernandez, Daniela T. Fuller, Weili Xu, Aimee E. Vozenilek, Yu Sato, Hiroyuki Jinnouchi, Sho Torii, Adam W. Turner, Hirokuni Akahori, Salome Kuntz, Craig C. Weinkauf, Parker J. Lee, Robert Kutys, Kathryn Harris, Alfred Lawrence Killey, Christina M. Mayhew, Matthew Ellis, Leah M. Weinstein, Neel V. Gadhoke, Roma Dhingra, Jeremy Ullman, Armella Dikongue, Maria E. Romero, Frank D. Kolodgie, Clint L. Miller, Renu Virmani, Aloke V. Finn

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Gene-educational attainment interactions in a multi-population genome-wide meta-analysis identify novel lipid loci by Lisa de las Fuentes, Lisa de las Fuentes, Karen L. Schwander, Karen L. Schwander, Michael R. Brown, Amy R. Bentley, Thomas W. Winkler, Yun Ju Sung, Yun Ju Sung, Patricia B. Munroe, Patricia B. Munroe, Clint L. Miller, Clint L. Miller, Clint L. Miller, Hugo Aschard, Hugo Aschard, Stella Aslibekyan, Traci M. Bartz, Traci M. Bartz, Lawrence F. Bielak, Jin Fang Chai, Ching-Yu Cheng, Ching-Yu Cheng, Rajkumar Dorajoo, Mary F. Feitosa, Xiuqing Guo, Fernando P. Hartwig, Fernando P. Hartwig, Andrea Horimoto, Ivana Kolčić, Ivana Kolčić, Elise Lim, Yongmei Liu, Alisa K. Manning, Alisa K. Manning, Jonathan Marten, Solomon K. Musani, Raymond Noordam, Sandosh Padmanabhan, Tuomo Rankinen, Melissa A. Richard, Paul M. Ridker, Paul M. Ridker, Albert V. Smith, Albert V. Smith, Dina Vojinovic, Dina Vojinovic, Alan B. Zonderman, Alan B. Zonderman, Maris Alver, Mathilde Boissel, Mathilde Boissel, Kaare Christensen, Barry I. Freedman, Chuan Gao, Franco Giulianini, Sarah E. Harris, Sarah E. Harris, Meian He, Fang-Chi Hsu, Brigitte Kühnel, Brigitte Kühnel, Federica Laguzzi, Xiaoyin Li, Xiaoyin Li, Leo-Pekka Lyytikäinen, Leo-Pekka Lyytikäinen, Ilja M. Nolte, Alaitz Poveda, Rainer Rauramaa, Muhammad Riaz, Muhammad Riaz, Antonietta Robino, Tamar Sofer, Fumihiko Takeuchi, Bamidele O. Tayo, Peter J. van der Most, Niek Verweij, Erin B. Ware, Stefan Weiss, Stefan Weiss, Wanqing Wen, Lisa R. Yanek, Yiqiang Zhan, Najaf Amin, Dan E. Arking, Christie Ballantyne, Christie Ballantyne, Eric Boerwinkle, Eric Boerwinkle, Jennifer A. Brody, Ulrich Broeckel, Archie Campbell, Archie Campbell, Mickaël Canouil, Mickaël Canouil, Xiaoran Chai, Yii-Der Ida Chen, Xu Chen, Kumaraswamy Naidu Chitrala, Maria Pina Concas, Ulf de Faire, Renée de Mutsert, H. Janaka de Silva, Paul S. de Vries, Ahn Do, Ahn Do, Jessica D. Faul, Virginia Fisher, James S. Floyd, Terrence Forrester, Yechiel Friedlander, Giorgia Girotto, C. Charles Gu, Göran Hallmans, Sami Heikkinen, Chew-Kiat Heng, Chew-Kiat Heng, Georg Homuth, Steven Hunt, Steven Hunt, M. Arfan Ikram, David R. Jacobs, Maryam Kavousi, Chiea Chuen Khor, Tuomas O. Kilpeläinen, Tuomas O. Kilpeläinen, Woon-Puay Koh, Woon-Puay Koh, Pirjo Komulainen, Carl D. Langefeld, Jingjing Liang, Kiang Liu, Jianjun Liu, Kurt Lohman, Reedik Mägi, Ani W. Manichaikul, Colin A. McKenzie, Thomas Meitinger, Thomas Meitinger, Yuri Milaneschi, Matthias Nauck, Matthias Nauck, Christopher P. Nelson, Christopher P. Nelson, Jeffrey R. O’Connell, Jeffrey R. O’Connell, Nicholette D. Palmer, Alexandre C. Pereira, Thomas Perls, Annette Peters, Annette Peters, Ozren Polašek, Ozren Polašek, Olli T. Raitakari, Olli T. Raitakari, Olli T. Raitakari, Kenneth Rice, Treva K. Rice, Stephen S. Rich, Charumathi Sabanayagam, Charumathi Sabanayagam, Pamela J. Schreiner, Xiao-Ou Shu, Stephen Sidney, Mario Sims, Jennifer A. Smith, Jennifer A. Smith, John M. Starr, John M. Starr, Konstantin Strauch, Konstantin Strauch, E. Shyong Tai, E. Shyong Tai, E. Shyong Tai, Kent D. Taylor, Michael Y. Tsai, André G. Uitterlinden, André G. Uitterlinden, Diana van Heemst, Melanie Waldenberger, Melanie Waldenberger, Melanie Waldenberger, Ya-Xing Wang, Wen-Bin Wei, Gregory Wilson, Deng Xuan, Jie Yao, Caizheng Yu, Jian-Min Yuan, Jian-Min Yuan, Wei Zhao, Diane M. Becker, Amélie Bonnefond, Amélie Bonnefond, Amélie Bonnefond, Donald W. Bowden, Richard S. Cooper, Ian J. Deary, Ian J. Deary, Jasmin Divers, Tõnu Esko, Tõnu Esko, Paul W. Franks, Paul W. Franks, Paul W. Franks, Philippe Froguel, Philippe Froguel, Philippe Froguel, Christian Gieger, Christian Gieger, Jost B. Jonas, Jost B. Jonas, Jost B. Jonas, Norihiro Kato, Timo A. Lakka, Timo A. Lakka, Timo A. Lakka, Karin Leander, Terho Lehtimäki, Terho Lehtimäki, Patrik K. E. Magnusson, Kari E. North, Ioanna Ntalla, Ioanna Ntalla, Brenda Penninx, Nilesh J. Samani, Nilesh J. Samani, Harold Snieder, Beatrice Spedicati, Pim van der Harst, Henry Völzke, Henry Völzke, Lynne E. Wagenknecht, David R. Weir, Mary K. Wojczynski, Tangchun Wu, Wei Zheng, Xiaofeng Zhu, Claude Bouchard, Daniel I. Chasman, Daniel I. Chasman, Michele K. Evans, Michele K. Evans, Ervin R. Fox, Vilmundur Gudnason, Vilmundur Gudnason, Caroline Hayward, Bernardo L. Horta, Sharon L. R. Kardia, Jose Eduardo Krieger, Dennis O. Mook-Kanamori, Dennis O. Mook-Kanamori, Patricia A. Peyser, Michael M. Province, Bruce M. Psaty, Bruce M. Psaty, Bruce M. Psaty, Igor Rudan, Xueling Sim, Blair H. Smith, Rob M. van Dam, Rob M. van Dam, Cornelia M. van Duijn, Cornelia M. van Duijn, Tien Yin Wong, Tien Yin Wong, Donna K. Arnett, Dabeeru C. Rao, James Gauderman, Ching-Ti Liu, Alanna C. Morrison, Jerome I. Rotter, Myriam Fornage, Myriam Fornage

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