Chimeric Antigen Receptor Signaling Domains Differentially Regulate Proliferation and Native T Cell Receptor Function in Virus-Specific T Cells by Bilal Omer, Bilal Omer, Paul A. Castillo, Haruko Tashiro, Thomas Shum, Mai T. A. Huynh, Mara Cardenas, Miyuki Tanaka, Andrew Lewis, Tim Sauer, Robin Parihar, Robin Parihar, Natalia Lapteva, Michael Schmueck-Henneresse, Malini Mukherjee, Stephen Gottschalk, Stephen Gottschalk, Stephen Gottschalk, Cliona M. Rooney, Cliona M. Rooney, Cliona M. Rooney, Cliona M. Rooney

Get full text

A strategy to protect off-the-shelf cell therapy products using virus-specific T-cells engineered to eliminate alloreactive T-cells by David H. Quach, Luis Becerra-Dominguez, Rayne H. Rouce, Cliona M. Rooney

Get full text

Anti-Tumor Effects after Adoptive Transfer of IL-12 Transposon-Modified Murine Splenocytes in the OT-I-Melanoma Mouse Model. by Daniel L Galvan, Richard T O'Neil, Aaron E Foster, Leslie Huye, Adham Bear, Cliona M Rooney, Matthew H Wilson

Get full text

Transposon-modified antigen-specific T lymphocytes for sustained therapeutic protein delivery in vivo by Richard T. O’Neil, Sunandan Saha, Ruth Ann Veach, Richard C. Welch, Lauren E. Woodard, Cliona M. Rooney, Matthew H. Wilson

Get full text

Robust and cost effective expansion of human regulatory T cells highly functional in a xenograft model of graft-versus-host disease by Rikhia Chakraborty, Aruna Mahendravada, Serena K. Perna, Cliona M. Rooney, Helen E. Heslop, Juan F. Vera, Barbara Savoldo, Gianpietro Dotti

Get full text

Rejection resistant CD30.CAR-modified Epstein-Barr virus-specific T cells as an off-the-shelf platform for CD30+ lymphoma by David H. Quach, Haran R. Ganesh, Yolanda D. Briones, Nazila Nouraee, Audrey Ma, Yezan F. Hadidi, Sandhya Sharma, Cliona M. Rooney

Get full text

Tonic 4-1BB Costimulation in Chimeric Antigen Receptors Impedes T Cell Survival and Is Vector-Dependent by Diogo Gomes-Silva, Malini Mukherjee, Madhuwanti Srinivasan, Giedre Krenciute, Olga Dakhova, Yueting Zheng, Joaquim M.S. Cabral, Cliona M. Rooney, Jordan S. Orange, Malcolm K. Brenner, Maksim Mamonkin

Get full text

Longitudinal analysis of the evolution of cellular immunity to SARS-CoV-2 induced by infection and vaccination by Spyridoula Vasileiou, Manik Kuvalekar, Yovana Velazquez, Ayumi Watanabe, Mansi Narula, Aster G. Workineh, Matthew French-Kim, Alejandro Torres Chavez, Sarah Gilmore, Cliona M. Rooney, Ann M. Leen

Get full text

Naive T cells inhibit the outgrowth of intractable antigen-activated memory T cells: implications for T-cell immunotherapy by Malcolm K Brenner, Cliona M Rooney, Sandhya Sharma, Birju Mehta, Helen E Heslop, Michael Schmueck-Henneresse, Huimin Zhang, Mae Woods, Naren U Mehta, Tim Sauer, Kathan S Parikh

Get full text

Highly Efficient Genome Editing of Murine and Human Hematopoietic Progenitor Cells by CRISPR/Cas9 by Michael C. Gundry, Lorenzo Brunetti, Angelique Lin, Allison E. Mayle, Ayumi Kitano, Dimitrios Wagner, Joanne I. Hsu, Kevin A. Hoegenauer, Cliona M. Rooney, Margaret A. Goodell, Daisuke Nakada

Get full text

Enhanced Expression of Anti-CD19 Chimeric Antigen Receptor in piggyBac Transposon-Engineered T Cells by Daisuke Morita, Nobuhiro Nishio, Shoji Saito, Miyuki Tanaka, Nozomu Kawashima, Yusuke Okuno, Satoshi Suzuki, Kazuyuki Matsuda, Yasuhiro Maeda, Matthew H. Wilson, Gianpietro Dotti, Cliona M. Rooney, Yoshiyuki Takahashi, Yozo Nakazawa

Get full text

A New Method for Reactivating and Expanding T Cells Specific for Rhizopus oryzae by Paul Castillo, Kaylor E. Wright, Dimitrios P. Kontoyiannis, Thomas Walsh, Shabnum Patel, Elizabeth Chorvinsky, Swaroop Bose, Yasmin Hazrat, Bilal Omer, Nathaniel Albert, Ann M. Leen, Cliona M. Rooney, Catherine M. Bollard, Conrad Russell Y. Cruz

Get full text

24 HIV-specific, ex vivo expanded T cell therapy (HXTC) for HIV clearance: feasibility, safety and efficacy by Julia M. Sung, JoAnnD Kuruc, Matthew Clohosey, Amanda Crooks, Shabnum Patel, Lauren Roesch, Patrick Hanley, CRussell Cruz, Nancie Archin, JosephJ Eron, Nilu Goonetilleke, Cliona M. Rooney, Catherine M. Bollard, David M. Margolis, Cynthia L. Gay

Get full text

Optimizing the production of suspension cells using the G-Rex “M” series by Pradip Bajgain, Roopa Mucharla, John Wilson, Dan Welch, Usanarat Anurathapan, Bitao Liang, Xiaohua Lu, Kyle Ripple, John M Centanni, Christine Hall, David Hsu, Larry A Couture, Shubhranshu Gupta, Adrian P Gee, Helen E Heslop, Ann M Leen, Cliona M Rooney, Juan F Vera

Get full text

Allogeneic, off-the-shelf, SARS-CoV-2-specific T cells (ALVR109) for the treatment of COVID-19 in high-risk patients by Spyridoula Vasileiou, LaQuisa Hill, Manik Kuvalekar, Aster G. Workineh, Ayumi Watanabe, Yovana Velazquez, Suhasini Lulla, Kimberly Mooney, Natalia Lapteva, Bambi J. Grilley, Helen E. Heslop, Cliona M. Rooney, Malcolm K. Brenner, Todd N. Eagar, George Carrum, Kevin A. Grimes, Ann M. Leen, Premal Lulla

Get full text

Multi-antigen-targeted T-cell therapy to treat patients with relapsed/refractory breast cancer by Valentina Hoyos, Spyridoula Vasileiou, Manik Kuvalekar, Ayumi Watanabe, Ifigeneia Tzannou, Yovana Velazquez, Matthew French-Kim, Wingchi Leung, Suhasini Lulla, Catherine Robertson, Claudette Foreman, Tao Wang, Shaun Bulsara, Natalia Lapteva, Bambi Grilley, Matthew Ellis, Charles Kent Osborne, Angela Coscio, Julie Nangia, Helen E. Heslop, Cliona M. Rooney, Juan F. Vera, Premal Lulla, Mothaffar Rimawi, Ann M. Leen

Get full text

Book of Abstracts: 2019 Health Equity Summer Research Summit Organized by the Center of Excellence in Health Equity, Training and Research, Baylor College of Medicine, Houston, Tex... by A Uribe-Gomez, Abraham A. Salinas-Miranda, MD, PhD, Acara E. Turner, BS, Adriana M. Strutt, PhD, ABPP, Adrienne Joseph, BS, Alex Wright, BS, Alexander C. Martin, BS, Alexis N. Milton, BS, Amelia Khoei, BS, Amritha Kanakamedala, BA, Angie Iyinbor, BA, Anna O’Neal, BS, Asha Morrow, MD, Ashley M. Butler, PhD, Ashley Young, BS, Asim Shah, MD, Asna Matin, MD, Audrey E. Christiansen, PhD, Boubakari Ibrahimou, PhD, Breanna Alonzo, Chase Ossenkop, BS, Carli O’Neal, BS, Chih-Wei Hsu, PhD, Charles Ikeanyionwu, BS, Chinwe Anyanwu, MPH, Charlotte Rivas, BS, Chioma A. Ikedionwu, BS, Chioma Anugwom, BS, Christopher R. Broda, MD, Claire Bocchini, MD, Claire Cummins, MD, Cliona M. Rooney, PhD, Colton L. Keo-Meier, PhD, Connor Johnson, BS, Courtney Miller-Chism, MD, Courtney Titus, MEd, Crystal L. Parker, MPH, Cylaina Bird, BA, Daniel Mauck, MPH, David Persse, MD, FACEP, Deborah A. Austin, PhD, Deepa Dongarwar, MS, Deepa V. Cherla, MD, Dwayne Wolf, MD, Ph.D, Eleanor Bimla Schwartz, MD, MS, Elena Petrova, PhD, Elias Perli, BS, Elisabeth Shell, PhD, PA-C, Elizabeth U. Tran, MD, Elsa Baena, PhD, Elyse Lopez, BS, Estrellita “Lo” Berry, MPA, Evadne Rodriguez, BA, Fabrizia Faustinella, MD, PhD, FACP, Faith D. Ihekweazu, MD, MS, Faiz Jiwani, MD, MS, Gabriella P. Chmaitelli, BS, Galant Chan, MD, Haijun Wang, PhD, MPH, Hamisu M. Salihu, MD, PhD, Hannah L. Combs, PhD, Hayley Rogers, BS, Heather Haq, MD, MHS, Iberia Romina Sosa, MD, PhD, Irene E. Jose, BS, Isabel Griffin, MPH, J. Cao, Jane Montealegre, PhD, Jason L. Salemi, PhD, MPH, Jennifer Chang, PhD, Jennifer M. Stinson, PhD, JL Mills, Joann Schulte, DO, MPH, Joel Thomas, John Prochaska, PhD, John Saunders, MD, MS, Jonathan Go, BBA, Jonathan Lim, MD, Jordan Salley, BS, Josue Estiven Pineda, BS, Jules Tabilona, MD, Julie L. Holihan, MD, MS, Kanika Bowen-Jallow, MD, MMS, Karla Bernardi, MD, Karla Fredricks, MD, MPH, Katherine B. Salciccioli, MD, Keila N. Lopez, MD,MPH, Kenneth Barning, MD, Kevin Dat Vuong, MA, Korede K. Yusuf, MBBS, PhD, Kristopher Myers, MPH, Kyle Wilson, Larry E. Laufman, EdD, Latanya J. Love, MD, Lauren Nolan, BA, Lauren Schoen, Lillian Huang, MD, Lindsey M. King, PhD, MPH, Lisa F. Nunez, BS, Louis Brown, PhD, Luna Hernandez, Lynn Hydod, M. Agustina Rossetti, PhD, Madeleine Allman, MPH, Mahmood Khan, MD, Makenna Marty, MAS, MaKenzie D. Lee, BS, Maria A. Jaramillo, BS, Maria Vigil, BS, Mariaelena Boyle, Marina Masciale, MD, Marisa Hilliard, PhD, Marisela Munoz, Mary E. Dickinson, PhD, Meishon Bell, MS, Michele K. York, PhD, Michelle Loor, MD, Michelle Lopez, MD, MPH, Mike K. Liang, MD, Moez Karim Aziz, MSECE, Moriel Karla, BS, Nancy Osazuma, Natalya Ramirez, BS, Natasha Navejar, BS, Nicolás Cortés-Penfield, MD, Nicole B. Lyons, BS, Norma Perez, MD, DrPH, NR Barshes, Olivia A. Barron, BA, Oscar A. Olavarria, MD, Petra Constable, BA, Phyllis Nwokolo, BS, Precious Omokaro, BS, Premal Patel, MD, Prithvi Vallabh, BS, Puja Shah, BA, Rafeek A. Yusuf, MD, MS, MPH, Rebecca A. Rosero, BA, Rebecca Lunstroth, JD, MA, Renice Obure, MPH, Robert Beach, MD, Robin Goin-Kochel, PhD, Robin Parihar, MD, PhD, Roger Zoorob, MD, MPH, Ronee E. Wilson, PhD, Rosa Michelle Schmidt, MD, MPH, Rowland Pettit, BS, Sade C. Udoetuk, MD, Sadia Tasnim, Sara Khan, BA, Sareema Adnan, BS, Sean Rodriguez, BA, Sharmila Anandasabapathy, MD, Shawna Nesbitt, MD, Sheena Bhushan, MD, Sherene Sharath, SO Rogers, Son Dinh, BSA, Sophia Banu, MD, Stacey Rose, MD, FACP, Stacy Drake, Ph.D, MPH, RN, AFN-BC, D-AB, Stephanie Morain, PhD, MPH, Stephen R. McCauley, PhD, Sue Abdelaziz, BS, Tahir Malik, BS, Tara L. Rasmussen, PhD, Thomas Shum, Tiana Raphel, BA, Tien C. Ko, MD, Toi Harris, MD, Trevor Hadley, BS, Uchechukwu Akoma, BS, Uwem Bridgette Eduok, BSA, Victoria Armendariz, MS, Yasmin C. Cole-Lewis, PhD, MPH, Zaina Al-Mohtaseb, MD, Zenab Yusuf, MD, MPH

Get full text