Activation of PPARbeta/delta causes a psoriasis-like skin disease in vivo. por Malgorzata Romanowska, Louise Reilly, Colin N A Palmer, Mattias C U Gustafsson, John Foerster

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PPARα Is Required for PPARδ Action in Regulation of Body Weight and Hepatic Steatosis in Mice por Wojciech G. Garbacz, Jeffrey T. J. Huang, Larry G. Higgins, Walter Wahli, Colin N. A. Palmer

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Cohort profile: The Scottish SHARE Mental Health (SHARE-MH) cohort – linkable survey, genetic and routinely collected data for mental health research por Andrew McIntosh, Matthew Henry Iveson, Colin N A Palmer, Emily L Ball, Jason Doherty, Carys Pugh, Shobna Vashishta

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Genetic and pharmacological relationship between P-glycoprotein and increased cardiovascular risk associated with clarithromycin prescription: An epidemiological and genomic popula... por Ify R Mordi, Benjamin K Chan, N David Yanez, Colin N A Palmer, Chim C Lang, James D Chalmers

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A Genome-wide Association Study Provides Evidence of Sex-specific Involvement of Chr1p35.1 (ZSCAN20-TLR12P) and Chr8p23.1 (HMGB1P46) With Diabetic Neuropathic Pain por Weihua Meng, Harshal A. Deshmukh, Louise A. Donnelly, Nicola Torrance, Helen M. Colhoun, Colin N.A. Palmer, Blair H. Smith

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A qualitative study on perceptions and practices of diabetes prevention and management in rural south India por Natarajan Lakshmi, Ranjit Mohan Anjana, Elizabeth C Rhodes, Vigasini Nora, Hari Rakesh, Colin N A Palmer, Viswanathan Mohan, Rajendra Pradeepa

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Conditional Expression of Human PPARδ and a Dominant Negative Variant of hPPARδ In Vivo por Larry G. Higgins, Wojciech G. Garbacz, Mattias C. U. Gustafsson, Sitheswaran Nainamalai, Peter R. Ashby, C. Roland Wolf, Colin N. A. Palmer

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A study on the health and socioeconomic impact of COVID-19 pandemic and barriers to self-management of diabetes during the lockdown among rural residents of South India por Natarajan Lakshmi, Ranjit Mohan Anjana, Moneeza Siddiqui, Sait Sonie, Ewan R Pearson, Alexander Doney, Colin N A Palmer, Viswanathan Mohan, Rajendra Pradeepa

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Metabolic dysfunction-related liver disease as a risk factor for cancer por Ewan R Pearson, Colin N A Palmer, Alasdair Taylor, Moneeza K Siddiqui, Philip Ambery, Javier Armisen, Benjamin G Challis, Carolina Haefliger, Alex S F Doney

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Polymorphism in INSR Locus Modifies Risk of Atrial Fibrillation in Patients on Thyroid Hormone Replacement Therapy por Enrique Soto-Pedre, Moneeza K. Siddiqui, Cyrielle Maroteau, Adem Y. Dawed, Alex S. Doney, Colin N. A. Palmer, Ewan R. Pearson, Graham P. Leese, Graham P. Leese

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Carrier status for the common R501X and 2282del4 filaggrin mutations is not associated with hearing phenotypes in 5,377 children from the ALSPAC cohort. por Santiago Rodriguez, Amanda J Hall, Raquel Granell, W H Irwin McLean, Alan D Irvine, Colin N A Palmer, George Davey Smith, John Henderson, Ian N M Day

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Genetic Variation in Kruppel like Factor 15 Is Associated with Left Ventricular Hypertrophy in Patients with Type 2 Diabetes: Discovery and Replication Cohorts por Sheila K. Patel, Bryan Wai, Chim C. Lang, Daniel Levin, Colin N.A. Palmer, Helen M. Parry, Elena Velkoska, Stephen B. Harrap, Piyush M. Srivastava, Louise M. Burrell

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Gene-environment interaction in the onset of eczema in infancy: filaggrin loss-of-function mutations enhanced by neonatal cat exposure. por Hans Bisgaard, Angela Simpson, Colin N A Palmer, Klaus Bønnelykke, Irwin McLean, Somnath Mukhopadhyay, Christian B Pipper, Liselotte B Halkjaer, Brian Lipworth, Jenny Hankinson, Ashley Woodcock, Adnan Custovic

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Deep-learning prediction of cardiovascular outcomes from routine retinal images in individuals with type 2 diabetes por Mohammad Ghouse Syed, Emanuele Trucco, Muthu R. K. Mookiah, Chim C. Lang, Rory J. McCrimmon, Colin N. A. Palmer, Ewan R. Pearson, Alex S. F. Doney, Ify R. Mordi

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The cholesterol-lowering effect of statins is modified by LILRB5 intolerance genotype: Results from a recruit-by-genotype clinical trial por Aleksi Tornio, Aleksi Tornio, Aleksi Tornio, Margherita Bigossi, Margherita Bigossi, Moneeza K. Siddiqui, Gwen Kennedy, Ala’a Melhem, Mehul K. Chourasia, Cyrielle Maroteau, Roberto Pola, Daniel I. Chasman, Alexander S. F. Doney, Colin N. A. Palmer

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Application of pharmacogenomics and bioinformatics to exemplify the utility of human ex vivo organoculture models in the field of precision medicine. por Karen Cowan, Graeme Macluskie, Michael Finch, Colin N A Palmer, Jane Hair, Max Bylesjo, Sarah Lynagh, Pamela Brankin, Marian McNeil, Carolyn Low, David Mallinson, Elaine M Gourlay, Hannah Child, Linda Cheyne, David C Bunton

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Cohort profile: DOLORisk Dundee: a longitudinal study of chronic neuropathic pain por Claire Jones, Blair H. Smith, Geert Crombez, Harry L. Hébert, Abirami Veluchamy, Georgios Baskozos, Francesca Fardo, Dimitri M. L. Van Ryckeghem, Mathilde M. V. Pascal, Keith Milburn, Ewan R. Pearson, David L. H. Bennett, Weihua Meng, Colin N. A. Palmer

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Competing risks analysis for neutrophil to lymphocyte ratio as a predictor of diabetic retinopathy incidence in the Scottish population por Aravind Lathika Rajendrakumar, Simona M. Hapca, Anand Thakarakkattil Narayanan Nair, Yu Huang, Mehul Kumar Chourasia, Ryan Shun-Yuen Kwan, Charvi Nangia, Moneeza K. Siddiqui, Prathiba Vijayaraghavan, Shona Z. Matthew, Graham P. Leese, Viswanathan Mohan, Ewan R. Pearson, Alexander S. F. Doney, Colin N. A. Palmer

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Amino acid homeostasis is a target of metformin therapy por Calum Forteath, Ify Mordi, Raid Nisr, Erika J. Gutierrez-Lara, Noor Alqurashi, Iain R. Phair, Amy R. Cameron, Craig Beall, Ibrahim Bahr, Mohapradeep Mohan, Aaron K.F. Wong, Adel Dihoum, Anwar Mohammad, Colin N.A. Palmer, Douglas Lamont, Kei Sakamoto, Benoit Viollet, Marc Foretz, Chim C. Lang, Graham Rena

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LTA4H rs2660845 association with montelukast response in early and late-onset asthma. por Cyrielle Maroteau, Antonio Espuela-Ortiz, Esther Herrera-Luis, Sundararajan Srinivasan, Fiona Carr, Roger Tavendale, Karen Wilson, Natalia Hernandez-Pacheco, James D Chalmers, Steve Turner, Somnath Mukhopadhyay, Anke-Hilse Maitland-van der Zee, Esteban G Burchard, Maria Pino-Yanes, Simon Young, Glenda Lassi, Adam Platt, Colin N A Palmer, PiCA Consortium

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