Connecting Metabolic Rewiring With Phenotype Switching in Melanoma 由 Paola Falletta, Paola Falletta, Colin R. Goding, Yurena Vivas-García

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TPC1 regulates melanoma tumourigenesis via mTORC1 and TFEB 由 Xuhui Jin, Ali A. Hanbashi, Faroq Kamli, Xiaoqi Pan, Colin R. Goding, John Parrington

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The protective role of MC1R in chromosome stability and centromeric integrity in melanocytes 由 Xin Li, Weiwei Mao, Jie Chen, Colin R. Goding, Rutao Cui, Zhi-Xiang Xu, Xiao Miao

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The MITF-SOX10 regulated long non-coding RNA DIRC3 is a melanoma tumour suppressor. 由 Elizabeth A Coe, Jennifer Y Tan, Michael Shapiro, Pakavarin Louphrasitthiphol, Andrew R Bassett, Ana C Marques, Colin R Goding, Keith W Vance

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A TFEB nuclear export signal integrates amino acid supply and glucose availability 由 Linxin Li, Hans J. Friedrichsen, Sarah Andrews, Sarah Picaud, Laurent Volpon, Kaochin Ngeow, Georgina Berridge, Roman Fischer, Katherine L. B. Borden, Panagis Filippakopoulos, Colin R. Goding

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Hypoxia at 3D organoid establishment selects essential subclones within heterogenous pancreatic cancer 由 Koichiro Kumano, Hiromitsu Nakahashi, Pakavarin Louphrasitthiphol, Pakavarin Louphrasitthiphol, Yukihito Kuroda, Yoshihiro Miyazaki, Osamu Shimomura, Shinji Hashimoto, Yoshimasa Akashi, Bryan J. Mathis, Jaejeong Kim, Yohei Owada, Colin R. Goding, Tatsuya Oda

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The integrated stress response effector ATF4 is an obligatory metabolic activator of NRF2 由 Julia Katharina Charlotte Kreß, Christina Jessen, Anita Hufnagel, Werner Schmitz, Thamara Nishida Xavier da Silva, Ancély Ferreira dos Santos, Laura Mosteo, Colin R. Goding, José Pedro Friedmann Angeli, Svenja Meierjohann

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Establishment of a fluorescent reporter of RNA-polymerase II activity to identify dormant cells 由 Rasmus Freter, Paola Falletta, Omid Omrani, Mahdi Rasa, Katharine Herbert, Francesco Annunziata, Alberto Minetti, Anna Krepelova, Lisa Adam, Sandra Käppel, Tina Rüdiger, Zhao-Qi Wang, Colin R. Goding, Francesco Neri

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MITF induces escape from innate immunity in melanoma 由 Luis Sánchez-del-Campo, Román Martí-Díaz, María F. Montenegro, Rebeca González-Guerrero, Trinidad Hernández-Caselles, Enrique Martínez-Barba, Antonio Piñero-Madrona, Juan Cabezas-Herrera, Colin R. Goding, José Neptuno Rodríguez-López

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Targeting MC1R depalmitoylation to prevent melanomagenesis in redheads 由 Shuyang Chen, Changpeng Han, Xiao Miao, Xin Li, Chengqian Yin, Junrong Zou, Min Liu, Shanshan Li, Lukasz Stawski, Bo Zhu, Qiong Shi, Zhi-Xiang Xu, Chunying Li, Colin R. Goding, Jun Zhou, Rutao Cui

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Acetylation reprograms MITF target selectivity and residence time 由 Pakavarin Louphrasitthiphol, Alessia Loffreda, Vivian Pogenberg, Sarah Picaud, Alexander Schepsky, Hans Friedrichsen, Zhiqiang Zeng, Anahita Lashgari, Benjamin Thomas, E. Elizabeth Patton, Matthias Wilmanns, Panagis Filippakopoulos, Jean-Philippe Lambert, Eiríkur Steingrímsson, Davide Mazza, Colin R. Goding

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Paradoxical activation of AMPK by glucose drives selective EP300 activity in colorectal cancer. 由 María Gutiérrez-Salmerón, José Manuel García-Martínez, Javier Martínez-Useros, María Jesús Fernández-Aceñero, Benoit Viollet, Severine Olivier, Jagat Chauhan, Silvia R Lucena, Antonio De la Vieja, Colin R Goding, Ana Chocarro-Calvo, Custodia García-Jiménez

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Mi-2β promotes immune evasion in melanoma by activating EZH2 methylation 由 Cang Li, Zhengyu Wang, Licheng Yao, Xingyu Lin, Yongping Jian, Yujia Li, Jie Zhang, Jingwei Shao, Phuc D. Tran, James R. Hagman, Meng Cao, Yusheng Cong, Hong-yu Li, Colin R. Goding, Zhi-Xiang Xu, Xuebin Liao, Xiao Miao, Rutao Cui

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NFIB Mediates BRN2 Driven Melanoma Cell Migration and Invasion Through Regulation of EZH2 and MITF 由 Mitchell E. Fane, Yash Chhabra, David E.J. Hollingsworth, Jacinta L. Simmons, Loredana Spoerri, Tae Gyu Oh, Jagat Chauhan, Toby Chin, Lachlan Harris, Tracey J. Harvey, George E.O. Muscat, Colin R. Goding, Richard A Sturm, Nikolas K. Haass, Glen M. Boyle, Michael Piper, Aaron G. Smith

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Stem cell senescence drives age-attenuated induction of pituitary tumours in mouse models of paediatric craniopharyngioma 由 Jose Mario Gonzalez-Meljem, Scott Haston, Gabriela Carreno, John R. Apps, Sara Pozzi, Christina Stache, Grace Kaushal, Alex Virasami, Leonidas Panousopoulos, Seyedeh Neda Mousavy-Gharavy, Ana Guerrero, Mamunur Rashid, Nital Jani, Colin R. Goding, Thomas S. Jacques, David J. Adams, Jesus Gil, Cynthia L. Andoniadou, Juan Pedro Martinez-Barbera

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BRN2 is a non-canonical melanoma tumor-suppressor 由 Michael Hamm, Pierre Sohier, Valérie Petit, Jérémy H. Raymond, Véronique Delmas, Madeleine Le Coz, Franck Gesbert, Colin Kenny, Zackie Aktary, Marie Pouteaux, Florian Rambow, Alain Sarasin, Nisamanee Charoenchon, Alfonso Bellacosa, Luis Sanchez-del-Campo, Laura Mosteo, Martin Lauss, Dies Meijer, Eirikur Steingrimsson, Göran B. Jönsson, Robert A. Cornell, Irwin Davidson, Colin R. Goding, Lionel Larue

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Lineage-specific roles of the cytoplasmic polyadenylation factor CPEB4 in the regulation of melanoma drivers 由 Eva Pérez-Guijarro, Panagiotis Karras, Metehan Cifdaloz, Raúl Martínez-Herranz, Estela Cañón, Osvaldo Graña, Celia Horcajada-Reales, Direna Alonso-Curbelo, Tonantzin G. Calvo, Gonzalo Gómez-López, Nicolas Bellora, Erica Riveiro-Falkenbach, Pablo L. Ortiz-Romero, José L. Rodríguez-Peralto, Lorena Maestre, Giovanna Roncador, Juan C. de Agustín Asensio, Colin R. Goding, Eduardo Eyras, Diego Megías, Raúl Méndez, María S. Soengas

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The protective role of DOT1L in UV-induced melanomagenesis 由 Bo Zhu, Shuyang Chen, Hongshen Wang, Chengqian Yin, Changpeng Han, Cong Peng, Zhaoqian Liu, Lixin Wan, Xiaoyang Zhang, Jie Zhang, Christine G. Lian, Peilin Ma, Zhi-xiang Xu, Sharon Prince, Tao Wang, Xiumei Gao, Yujiang Shi, Dali Liu, Min Liu, Wenyi Wei, Zhi Wei, Jingxuan Pan, Yongjun Wang, Zhenyu Xuan, Jay Hess, Nicholas K. Hayward, Colin R. Goding, Xiang Chen, Jun Zhou, Rutao Cui

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Gut microbiota dependent anti-tumor immunity restricts melanoma growth in Rnf5 −/− mice 由 Yan Li, Roberto Tinoco, Lisa Elmén, Igor Segota, Yibo Xian, Yu Fujita, Avinash Sahu, Raphy Zarecki, Kerrie Marie, Yongmei Feng, Ali Khateb, Dennie T. Frederick, Shiri K. Ashkenazi, Hyungsoo Kim, Eva Guijarro Perez, Chi-Ping Day, Rafael S. Segura Muñoz, Robert Schmaltz, Shibu Yooseph, Miguel A. Tam, Tongwu Zhang, Emily Avitan-Hersh, Lihi Tzur, Shoshana Roizman, Ilanit Boyango, Gil Bar-Sela, Amir Orian, Randal J. Kaufman, Marcus Bosenberg, Colin R. Goding, Bas Baaten, Mitchell P. Levesque, Reinhard Dummer, Kevin Brown, Glenn Merlino, Eytan Ruppin, Keith Flaherty, Amanda Ramer-Tait, Tao Long, Scott N. Peterson, Linda M. Bradley, Ze’ev A. Ronai

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