Regulation of developmentally controlled enhancer activity by extrinsic signals in normal and malignant cells: AP-1 at the centre by Alexander Maytum, Nadine Obier, Pierre Cauchy, Constanze Bonifer, Constanze Bonifer

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Standing at odds: mutated RAS and hematopoietic stem cells by Monica Nafria, Constanze Bonifer

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RUNX1-EVI1 disrupts lineage determination and the cell cycle by interfering with RUNX1 and EVI1 driven gene regulatory networks by Sophie G. Kellaway, Peter Keane, Ella Kennett, Constanze Bonifer

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t(8;21) Acute Myeloid Leukemia as a Paradigm for the Understanding of Leukemogenesis at the Level of Gene Regulation and Chromatin Programming by Sophie Kellaway, Paulynn S. Chin, Farnaz Barneh, Constanze Bonifer, Olaf Heidenreich

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C/EBPα overrides epigenetic reprogramming by oncogenic transcription factors in acute myeloid leukemia by Justin Loke, Paulynn Suyin Chin, Peter Keane, Anna Pickin, Salam A. Assi, Anetta Ptasinska, Maria Rosaria Imperato, Peter N. Cockerill, Constanze Bonifer

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Gene regulatory network analysis predicts cooperating transcription factor regulons required for FLT3-ITD+ AML growth by Daniel J.L. Coleman, Peter Keane, Rosario Luque-Martin, Paulynn S. Chin, Helen Blair, Luke Ames, Sophie G. Kellaway, James Griffin, Elizabeth Holmes, Sandeep Potluri, Salam A. Assi, John Bushweller, Olaf Heidenreich, Peter N. Cockerill, Constanze Bonifer

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Identification of gene specific cis-regulatory elements during differentiation of mouse embryonic stem cells: An integrative approach using high-throughput datasets. by M S Vijayabaskar, Debbie K Goode, Nadine Obier, Monika Lichtinger, Amber M L Emmett, Fatin N Zainul Abidin, Nisar Shar, Rebecca Hannah, Salam A Assi, Michael Lie-A-Ling, Berthold Gottgens, Georges Lacaud, Valerie Kouskoff, Constanze Bonifer, David R Westhead

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Pharmacological inhibition of RAS overcomes FLT3 inhibitor resistance in FLT3-ITD+ AML through AP-1 and RUNX1 by Daniel J.L. Coleman, Peter Keane, Paulynn S. Chin, Luke Ames, Sophie Kellaway, Helen Blair, Naeem Khan, James Griffin, Elizabeth Holmes, Alexander Maytum, Sandeep Potluri, Lara Strate, Kinga Koscielniak, Manoj Raghavan, John Bushweller, Olaf Heidenreich, Terry Rabbitts, Peter N. Cockerill, Constanze Bonifer

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Leukemic stem cells activate lineage inappropriate signalling pathways to promote their growth by Sophie G. Kellaway, Sandeep Potluri, Peter Keane, Helen J. Blair, Luke Ames, Alice Worker, Paulynn S. Chin, Anetta Ptasinska, Polina K. Derevyanko, Assunta Adamo, Daniel J. L. Coleman, Naeem Khan, Salam A. Assi, Anja Krippner-Heidenreich, Manoj Raghavan, Peter N. Cockerill, Olaf Heidenreich, Constanze Bonifer

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Small Molecule Inhibitor of CBFβ-RUNX Binding for RUNX Transcription Factor Driven Cancers by Anuradha Illendula, Jane Gilmour, Jolanta Grembecka, Venkata Sesha Srimath Tirumala, Adam Boulton, Aravinda Kuntimaddi, Charles Schmidt, Lixin Wang, John A. Pulikkan, Hongliang Zong, Mahmut Parlak, Cem Kuscu, Anna Pickin, Yunpeng Zhou, Yan Gao, Lauren Mishra, Mazhar Adli, Lucio H. Castilla, Roger A. Rajewski, Kevin A. Janes, Monica L. Guzman, Constanze Bonifer, John H. Bushweller

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Genome-scale clustered regularly interspaced short palindromic repeats screen identifies nucleotide metabolism as an actionable therapeutic vulnerability in diffuse large B-cell ly... by Nicholas Davies, Tegan Francis, Ceri Oldreive, Maria Azam, Jordan Wilson, Philip J. Byrd, Megan Burley, Archana Sharma-Oates, Peter Keane, Sael Alatawi, Martin R. Higgs, Zbigniew Rudzki, Maha Ibrahim, Tracey Perry, Angelo Agathaggelou, Anne-Marie Hewitt, Edward Smith, Constanze Bonifer, Mark O’Connor, Josep V. Forment, Paul G. Murray, Eanna Fennell, Gemma Kelly, Catherine Chang, Grant S. Stewart, Tatjana Stankovic, Marwan Kwok, Alexander Malcolm Taylor

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Transcriptional reprogramming by mutated IRF4 in lymphoma by Nikolai Schleussner, Pierre Cauchy, Vedran Franke, Maciej Giefing, Oriol Fornes, Naveen Vankadari, Salam A. Assi, Mariantonia Costanza, Marc A. Weniger, Altuna Akalin, Ioannis Anagnostopoulos, Thomas Bukur, Marco G. Casarotto, Frederik Damm, Oliver Daumke, Benjamin Edginton-White, J. Christof M. Gebhardt, Michael Grau, Stephan Grunwald, Martin-Leo Hansmann, Sylvia Hartmann, Lionel Huber, Eva Kärgel, Simone Lusatis, Daniel Noerenberg, Nadine Obier, Ulrich Pannicke, Anja Fischer, Anja Reisser, Andreas Rosenwald, Klaus Schwarz, Srinivasan Sundararaj, Andre Weilemann, Wiebke Winkler, Wendan Xu, Georg Lenz, Klaus Rajewsky, Wyeth W. Wasserman, Peter N. Cockerill, Claus Scheidereit, Reiner Siebert, Ralf Küppers, Rudolf Grosschedl, Martin Janz, Constanze Bonifer, Stephan Mathas

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