Smoothened transduces Hedgehog signals via activity-dependent sequestration of PKA catalytic subunits. Dahkki Corvin D Arveseth, John T Happ, Danielle S Hedeen, Ju-Fen Zhu, Jacob L Capener, Dana Klatt Shaw, Ishan Deshpande, Jiahao Liang, Jiewei Xu, Sara L Stubben, Isaac B Nelson, Madison F Walker, Kouki Kawakami, Asuka Inoue, Nevan J Krogan, David J Grunwald, Ruth Hüttenhain, Aashish Manglik, Benjamin R Myers

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GRK2 kinases in the primary cilium initiate SMOOTHENED-PKA signaling in the Hedgehog cascade. Dahkki Madison F Walker, Jingyi Zhang, William Steiner, Pei-I Ku, Ju-Fen Zhu, Zachary Michaelson, Yu-Chen Yen, Annabel Lee, Alyssa B Long, Mattie J Casey, Abhishek Poddar, Isaac B Nelson, Corvin D Arveseth, Falko Nagel, Ryan Clough, Sarah LaPotin, Kristen M Kwan, Stefan Schulz, Rodney A Stewart, John J G Tesmer, Tamara Caspary, Radhika Subramanian, Xuecai Ge, Benjamin R Myers

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