Functional assays with human patient-derived enteroid monolayers to assess the human gut barrier by Ibrahim M. Sayed, Courtney Tindle, Ayden G. Fonseca, Pradipta Ghosh, Soumita Das

Get full text

SPT6 loss permits the transdifferentiation of keratinocytes into an intestinal fate that resembles Barrett’s metaplasia by Daniella T. Vo, MacKenzie R. Fuller, Courtney Tindle, Mahitha Shree Anandachar, Soumita Das, Debashis Sahoo, Pradipta Ghosh

Get full text

COVID-19 lung disease shares driver AT2 cytopathic features with Idiopathic pulmonary fibrosis by Saptarshi Sinha, Vanessa Castillo, Celia R. Espinoza, Courtney Tindle, Ayden G. Fonseca, Jennifer M. Dan, Gajanan D. Katkar, Soumita Das, Debashis Sahoo, Pradipta Ghosh

Get full text

Artificial intelligence guided discovery of a barrier-protective therapy in inflammatory bowel disease by Debashis Sahoo, Lee Swanson, Ibrahim M. Sayed, Gajanan D. Katkar, Stella-Rita Ibeawuchi, Yash Mittal, Rama F. Pranadinata, Courtney Tindle, Mackenzie Fuller, Dominik L. Stec, John T. Chang, William J. Sandborn, Soumita Das, Pradipta Ghosh

Get full text

AI-assisted discovery of an ethnicity-influenced driver of cell transformation in esophageal and gastroesophageal junction adenocarcinomas by Pradipta Ghosh, Vinicius J. Campos, Daniella T. Vo, Caitlin Guccione, Vanae Goheen-Holland, Courtney Tindle, Guilherme S. Mazzini, Yudou He, Ludmil B. Alexandrov, Scott M. Lippman, Richard R. Gurski, Soumita Das, Rena Yadlapati, Kit Curtius, Debashis Sahoo

Get full text

Adult stem cell-derived complete lung organoid models emulate lung disease in COVID-19 by Courtney Tindle, MacKenzie Fuller, Ayden Fonseca, Sahar Taheri, Stella-Rita Ibeawuchi, Nathan Beutler, Gajanan Dattatray Katkar, Amanraj Claire, Vanessa Castillo, Moises Hernandez, Hana Russo, Jason Duran, Laura E Crotty Alexander, Ann Tipps, Grace Lin, Patricia A Thistlethwaite, Ranajoy Chattopadhyay, Thomas F Rogers, Debashis Sahoo, Pradipta Ghosh, Soumita Das

Get full text

The DNA glycosylase NEIL2 is protective during SARS-CoV-2 infection by Nisha Tapryal, Anirban Chakraborty, Kaushik Saha, Azharul Islam, Lang Pan, Koa Hosoki, Ibrahim M. Sayed, Jason M. Duran, Joshua Alcantara, Vanessa Castillo, Courtney Tindle, Altaf H. Sarker, Maki Wakamiya, Victor J. Cardenas, Gulshan Sharma, Laura E. Crotty Alexander, Sanjiv Sur, Debashis Sahoo, Gourisankar Ghosh, Soumita Das, Pradipta Ghosh, Istvan Boldogh, Tapas K. Hazra

Get full text

AI-guided discovery of the invariant host response to viral pandemics by Debashis Sahoo, Gajanan D. Katkar, Soni Khandelwal, Mahdi Behroozikhah, Amanraj Claire, Vanessa Castillo, Courtney Tindle, MacKenzie Fuller, Sahar Taheri, Thomas F. Rogers, Nathan Beutler, Sydney I. Ramirez, Stephen A. Rawlings, Victor Pretorius, Davey M. Smith, Dennis R. Burton, Laura E. Crotty Alexander, Jason Duran, Shane Crotty, Jennifer M. Dan, Soumita Das, Pradipta Ghosh

Get full text

Anticancer pan-ErbB inhibitors reduce inflammation and tissue injury and exert broad-spectrum antiviral effects by Sirle Saul, Marwah Karim, Luca Ghita, Pei-Tzu Huang, Winston Chiu, Verónica Durán, Chieh-Wen Lo, Sathish Kumar, Nishank Bhalla, Pieter Leyssen, Farhang Alem, Niloufar A. Boghdeh, Do H.N. Tran, Courtney A. Cohen, Jacquelyn A. Brown, Kathleen E. Huie, Courtney Tindle, Mamdouh Sibai, Chengjin Ye, Ahmed Magdy Khalil, Kevin Chiem, Luis Martinez-Sobrido, John M. Dye, Benjamin A. Pinsky, Pradipta Ghosh, Soumita Das, David E. Solow-Cordero, Jing Jin, John P. Wikswo, Dirk Jochmans, Johan Neyts, Steven De Jonghe, Aarthi Narayanan, Shirit Einav

Get full text