The Effect of Cumulative B*5703-Associated Escape Mutations on HIV-1 Replicative Capacity by Crawford, H, Prado, J, Brady, S, Leslie, A, Goulder, P

P09-18. Cw 0303/0304 HIV specific CTL response toward GagYL9 select for HIV escape variants with low fitness that is compensated by intra-codon variation by Honeyborne, I, Leslie, A, Crawford, H, Rousseau, C, Mullins, J, Walker, B, Goulder, P, Prado, J

Cw*0303/0304 HIV specific CTL response toward GagYL9 select for HIV escape variants with low fitness that is compensated by intra-codon variation by Honeyborne, I, Leslie, A, Crawford, H, Rousseau, C, Mullins, J, Walker, B, Goulder, P, Prado, J

A holistic approach to fragile X syndrome integrated guidance for person-centred care by Johnson, K, Stanfield, AC, Scerif, G, McKechanie, A, Clarke, A, Herring, J, Smith, K, Crawford, H

Evolution of HLA-B*5703 HIV-1 escape mutations and their impact on HIV-1 replicative capacity by Crawford, H, Lumm, W, Leslie, A, Schaefer, M, Boeras, D, Prado, J, Mulenga, J, Allen, S, Goulder, P, Hunter, E

The loss of ATRX increases susceptibility to pancreatic injury and oncogenic KRAS in female but not male mice by Young, C, Baker, R, Howlett, C, Hryciw, T, Herman, J, Higgs, D, Gibbons, R, Crawford, H, Brown, A, Pin, C

P09-17. Evolution of HLA-B*5703 HIV-1 escape mutations and their impact on HIV-1 replicative capacity by Crawford, H, Lumm, W, Leslie, A, Schaefer, M, Boeras, D, Prado, J, Mulenga, J, Allen, S, Goulder, P, Hunter, E

HIV-1 Adaptation to Antigen Processing Results in Population-Level Immune Evasion and Affects Subtype Diversification by Tenzer, S, Crawford, H, Crawford, H, Pymm, P, Pymm, P, Gifford, R, Sreenu, V, Weimershaus, M, deOliveira, T, deOliveira, T, Burgevin, A, Gerstoft, J, Akkad, N, Lunn, D, Fugger, L, Fugger, L, Bell, J, Schild, H, vanEndert, P, Iversen, A, Iversen, A

The hypervariable HIV-1 capsid protein residues comprise HLA-driven CD8+ T-cell escape mutations and covarying HLA-independent polymorphisms. by Crawford, H, Matthews, P, Schaefer, M, Carlson, J, Leslie, A, Kilembe, W, Allen, S, Ndung'u, T, Heckerman, D, Hunter, E, Goulder, P

Proliferative capacity of epitope-specific CD8 T-cell responses is inversely related to viral load in chronic human immunodeficiency virus type 1 infection. by Day, C, Kiepiela, P, Leslie, A, van der Stok, M, Nair, K, Ismail, N, Honeyborne, I, Crawford, H, Coovadia, H, Goulder, P, Walker, B, Klenerman, P

HLA Footprints on Human Immunodeficiency Virus Type 1 Are Associated with Interclade Polymorphisms and Intraclade Phylogenetic Clustering (vol 83, pg 4605, 2009) by Matthews, P, Leslie, A, Katzourakis, A, Crawford, H, Payne, R, Prendergast, A, Power, K, Kelleher, A, Klenerman, P, Carlson, J, Heckerman, D, Ndung'u, T, Walker, B, Allen, T, Pybus, O, Goulder, P

HLA footprints on human immunodeficiency virus type 1 are associated with interclade polymorphisms and intraclade phylogenetic clustering. by Matthews, P, Leslie, A, Katzourakis, A, Crawford, H, Payne, R, Prendergast, A, Power, K, Kelleher, A, Klenerman, P, Carlson, J, Heckerman, D, Ndung'u, T, Walker, B, Allen, T, Pybus, O, Goulder, P

HIV-1 adaptation to antigen processing results in population-level immune evasion and affects subtype diversification. by Tenzer, S, Crawford, H, Pymm, P, Gifford, R, Sreenu, V, Weimershaus, M, de Oliveira, T, Burgevin, A, Gerstoft, J, Akkad, N, Lunn, D, Fugger, L, Bell, J, Schild, H, van Endert, P, Iversen, A

Effective T-cell responses select human immunodeficiency virus mutants and slow disease progression. by Frater, A, Brown, H, Oxenius, A, Günthard, H, Hirschel, B, Robinson, N, Leslie, A, Payne, R, Crawford, H, Prendergast, A, Brander, C, Kiepiela, P, Walker, B, Goulder, P, McLean, A, Phillips, R

Evolution of HLA-B*5703 HIV-1 escape mutations in HLA-B*5703-positive individuals and their transmission recipients. by Crawford, H, Lumm, W, Leslie, A, Schaefer, M, Boeras, D, Prado, J, Tang, J, Farmer, P, Ndung'u, T, Lakhi, S, Gilmour, J, Goepfert, P, Walker, B, Kaslow, R, Mulenga, J, Allen, S, Goulder, P, Hunter, E

Fitness cost of escape mutations in p24 Gag in association with control of human immunodeficiency virus type 1. by Martinez-Picado, J, Prado, J, Fry, E, Pfafferott, K, Leslie, A, Chetty, S, Thobakgale, C, Honeyborne, I, Crawford, H, Matthews, P, Pillay, T, Rousseau, C, Mullins, J, Brander, C, Walker, B, Stuart, D, Kiepiela, P, Goulder, P

Compensatory mutation partially restores fitness and delays reversion of escape mutation within the immunodominant HLA-B*5703-restrieted gag epitope in chronic human immunodeficien... by Crawford, H, Prado, J, Leslie, A, Hue, S, Honeyborne, I, Reddy, S, van der Stok, M, Mncube, Z, Brander, C, Rousseau, C, Mullins, J, Kaslow, R, Goepfert, P, Allen, S, Hunter, E, Mulenga, J, Kiepiela, P, Walker, B, Goulder, P

Compensatory mutation partially restores fitness and delays reversion of escape mutation within the immunodominant HLA-B*5703-restricted Gag epitope in chronic human immunodeficien... by Crawford, H, Prado, J, Leslie, A, Hué, S, Honeyborne, I, Reddy, S, van der Stok, M, Mncube, Z, Brander, C, Rousseau, C, Mullins, J, Kaslow, R, Goepfert, P, Allen, S, Hunter, E, Mulenga, J, Kiepiela, P, Walker, B, Goulder, P

Central role of reverting mutations in HLA associations with human immunodeficiency virus set point. by Matthews, P, Prendergast, A, Leslie, A, Crawford, H, Payne, R, Rousseau, C, Rolland, M, Honeyborne, I, Carlson, J, Kadie, C, Brander, C, Bishop, K, Mlotshwa, N, Mullins, J, Coovadia, H, Ndung'u, T, Walker, B, Heckerman, D, Goulder, P

Control of human immunodeficiency virus type 1 is associated with HLA-B*13 and targeting of multiple gag-specific CD8+ T-cell epitopes. by Honeyborne, I, Prendergast, A, Pereyra, F, Leslie, A, Crawford, H, Payne, R, Reddy, S, Bishop, K, Moodley, E, Nair, K, van der Stok, M, McCarthy, N, Rousseau, C, Addo, M, Mullins, J, Brander, C, Kiepiela, P, Walker, B, Goulder, P