Neoadjuvant Therapy for Resectable Pancreatic Cancer: An Evolving Paradigm Shift by Akhil Chawla, Cristina R. Ferrone

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B7-H3-targeted CAR T cell activity is enhanced by radiotherapy in solid cancers by Marco Ventin, Giulia Cattaneo, Luke Maggs, Jingyu Jia, Shahrzad Arya, Soldano Ferrone, Soldano Ferrone, Xinhui Wang, Cristina R. Ferrone

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239 CSPG4-targeted CAR T cells demonstrate potent antitumor activity in an orthotopic murine model of anaplastic thyroid cancer by Cristina R Ferrone, Soldano Ferrone, Giulia Cattaneo, Marco Ventin, Venkata Rao Vantaku, Shahrzad Arya, Jingyu Jia, Luke Maggs, Xinhui Wang, Sareh Parangi

Differential role of HLA-A and HLA-B, C expression levels as prognostic markers in colon and rectal cancer by Wilko Weichert, Lei Cai, Soldano Ferrone, Peter J K Kuppen, Lindy G Durrant, Theodoros Michelakos, Filippos Kontos, Tomohiro Kurokawa, Ananthan Sadagopan, Danielle Krijgsman, Cristina R Ferrone

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Case Report: BAP1 Mutation and RAD21 Amplification as Predictive Biomarkers to PARP Inhibitor in Metastatic Intrahepatic Cholangiocarcinoma by Francesco Sabbatino, Francesco Sabbatino, Luigi Liguori, Umberto Malapelle, Francesca Schiavi, Vincenzo Tortora, Valeria Conti, Valeria Conti, Amelia Filippelli, Amelia Filippelli, Giampaolo Tortora, Cristina R. Ferrone, Stefano Pepe, Stefano Pepe

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317 B7-H3-targeted CAR T cell with an inducible caspase 9 suicide gene effectively eradicates uveal melanoma liver metastases by Yi Sun, Cristina R Ferrone, Rizwan Haq, Soldano Ferrone, Genevieve M Boland, Sandra Ryeom, Russell W Jenkins, Giulia Cattaneo, Marco Ventin, Shahrzad Arya, Jingyu Jia, Luke Maggs, Xinhui Wang, Bruce R Ksander

Orthotopic and heterotopic murine models of pancreatic cancer and their different responses to FOLFIRINOX chemotherapy by Derek J. Erstad, Mozhdeh Sojoodi, Martin S. Taylor, Sarani Ghoshal, Allen A. Razavi, Katherine A. Graham-O'Regan, Nabeel Bardeesy, Cristina R. Ferrone, Michael Lanuti, Peter Caravan, Kenneth K. Tanabe, Bryan C. Fuchs

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A fast, simple, and cost-effective method of expanding patient-derived xenograft mouse models of pancreatic ductal adenocarcinoma by Zhenyang Liu, Michael Ho-Young Ahn, Tomohiro Kurokawa, Amy Ly, Gong Zhang, Fuyou Wang, Teppei Yamada, Ananthan Sadagopan, Jane Cheng, Cristina R. Ferrone, Andrew S. Liss, Kim C. Honselmann, Gregory R. Wojtkiewicz, Soldano Ferrone, Xinhui Wang

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Tumor engraftment in patient-derived xenografts of pancreatic ductal adenocarcinoma is associated with adverse clinicopathological features and poor survival. by Ilaria Pergolini, Vicente Morales-Oyarvide, Mari Mino-Kenudson, Kim C Honselmann, Matthew W Rosenbaum, Sabikun Nahar, Marina Kem, Cristina R Ferrone, Keith D Lillemoe, Nabeel Bardeesy, David P Ryan, Sarah P Thayer, Andrew L Warshaw, Carlos Fernández-Del Castillo, Andrew S Liss

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Response to Commentary on ‘“Long-Term Outcomes of Parenchyma-Sparing and Oncologic Resections in Patients With Nonfunctional Pancreatic Neuroendocrine Tumors <3 cm in a Large Multi... by Louisa Bolm, MD, Martina Nebbia, MD, Alice C. Wei, MD, Amer H. Zureikat, MD, Carlos Fernández-del Castillo, MD, Jian Zheng, MD, Alessandra Pulvirenti, MD, Ammar A. Javed, MD, Yurie Sekigami, MD, Natalie Petruch, Motaz Qadan, MD, PhD, Keith D. Lillemoe, MD, Jin He, MD, Cristina R. Ferrone, MD, the Pancreatic Neuroendocrine Disease Alliance (PANDA)

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CSPG4 CAR-redirected Cytokine Induced Killer lymphocytes (CIK) as effective cellular immunotherapy for HLA class I defective melanoma by Lidia Giraudo, Giulia Cattaneo, Loretta Gammaitoni, Ilenia Iaia, Chiara Donini, Annamaria Massa, Maria Laura Centomo, Marco Basiricò, Elisa Vigna, Alberto Pisacane, Franco Picciotto, Enrico Berrino, Caterina Marchiò, Alessandra Merlini, Luca Paruzzo, Stefano Poletto, Daniela Caravelli, Andrea Michela Biolato, Valentina Bortolot, Elisa Landoni, Marco Ventin, Cristina R. Ferrone, Massimo Aglietta, Gianpietro Dotti, Valeria Leuci, Fabrizio Carnevale-Schianca, Dario Sangiolo

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Response to Commentary “Are Parenchyma-Sparing Resections Really Appropriate for Small (<3 cm) Non-Functional Pancreatic Neuroendocrine Tumors?” by Louisa Bolm, MD, Martina Nebbia, MD, Alice C. Wei, MD, Amer H. Zureikat, MD, Carlos Fernández-del Castillo, MD, Jian Zheng, MD, Alessandra Pulvirenti, MD, Ammar A. Javed, MD, Yurie Sekigami, MD, Natalie Petruch, MD, Motaz Qadan, MD, PhD, Keith D. Lillemoe, MD, Jin He, MD, Cristina R. Ferrone, MD, the PAncreatic Neuroendocrine Disease Alliance (PANDA)

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Single-Cell RNA Sequencing Identifies Extracellular Matrix Gene Expression by Pancreatic Circulating Tumor Cells by David T. Ting, Ben S. Wittner, Matteo Ligorio, Nicole Vincent Jordan, Ajay M. Shah, David T. Miyamoto, Nicola Aceto, Francesca Bersani, Brian W. Brannigan, Kristina Xega, Jordan C. Ciciliano, Huili Zhu, Olivia C. MacKenzie, Julie Trautwein, Kshitij S. Arora, Mohammad Shahid, Haley L. Ellis, Na Qu, Nabeel Bardeesy, Miguel N. Rivera, Vikram Deshpande, Cristina R. Ferrone, Ravi Kapur, Sridhar Ramaswamy, Toshi Shioda, Mehmet Toner, Shyamala Maheswaran, Daniel A. Haber

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Stressed target cancer cells drive nongenetic reprogramming of CAR T cells and solid tumor microenvironment by Yufeng Wang, David L. Drum, Ruochuan Sun, Yida Zhang, Feng Chen, Fengfei Sun, Emre Dal, Ling Yu, Jingyu Jia, Shahrzad Arya, Lin Jia, Song Fan, Steven J. Isakoff, Allison M. Kehlmann, Gianpietro Dotti, Fubao Liu, Hui Zheng, Cristina R. Ferrone, Alphonse G. Taghian, Albert B. DeLeo, Marco Ventin, Giulia Cattaneo, Yongxiang Li, Youssef Jounaidi, Peigen Huang, Cristina Maccalli, Hanyu Zhang, Cheng Wang, Jibing Yang, Genevieve M. Boland, Ruslan I. Sadreyev, LaiPing Wong, Soldano Ferrone, Xinhui Wang

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