Human and Mouse Gastrointestinal Tumor Distribution is Selected According to a Basal Wnt Signalling Gradient by Rodenas-Cuadrado, P, Howarth, K, Lewis, A, Mallappa, S, Jeffery, R, Rodriguez-Justo, M, Clark, S, East, J, Travis, S, Tomlinson, I, Leedham, S

HUMAN AND MOUSE GASTROINTESTINAL TUMOUR DISTRIBUTION IS SELECTED ACCORDING TO A BASAL INTESTINAL WNT SIGNALLING GRADIENT by Rodenas-Cuadrado, P, Howarth, K, Lewis, A, Mallappa, S, Jeffry, R, Rodriguez-Justo, M, East, J, Travis, S, Clark, S, Tomlinson, I, Leedham, S

A basal gradient of Wnt and stem-cell number influences regional tumour distribution in human and mouse intestinal tracts. by Leedham, S, Rodenas-Cuadrado, P, Howarth, K, Lewis, A, Mallappa, S, Segditsas, S, Davis, H, Jeffery, R, Rodriguez-Justo, M, Keshav, S, Travis, S, Graham, T, East, J, Clark, S, Tomlinson, I

A basal gradient of Wnt and stem-cell number influences regional tumour distribution in human and mouse intestinal tracts by Leedham, S, Rodenas-Cuadrado, P, Howarth, K, Lewis, A, Mallappa, S, Segditsas, S, Davis, H, Jeffery, R, Rodriguez-Justo, M, Keshav, S, Travis, S, Graham, T, East, J, Clark, S, Tomlinson, I

Hereditary mixed polyposis syndrome is caused by a 40-kb upstream duplication that leads to increased and ectopic expression of the BMP antagonist GREM1 by Jaeger, E, Leedham, S, Lewis, A, Segditsas, S, Becker, M, Cuadrado, P, Davis, H, Kaur, K, Heinimann, K, Howarth, K, East, J, Taylor, J, Thomas, H, Tomlinson, I

Hereditary mixed polyposis syndrome is caused by a 40-kb upstream duplication that leads to increased and ectopic expression of the BMP antagonist GREM1. by Jaeger, E, Leedham, S, Lewis, A, Segditsas, S, Becker, M, Cuadrado, P, Davis, H, Kaur, K, Heinimann, K, Howarth, K, East, J, Taylor, J, Thomas, H, Tomlinson, I

Aberrant epithelial GREM1 expression initiates colonic tumorigenesis from cells outside the stem cell niche. by Davis, H, Irshad, S, Bansal, M, Rafferty, H, Boitsova, T, Bardella, C, Jaeger, E, Lewis, A, Freeman-Mills, L, Giner, F, Rodenas-Cuadrado, P, Mallappa, S, Clark, S, Thomas, H, Jeffery, R, Poulsom, R, Rodriguez-Justo, M, Novelli, M, Chetty, R, Silver, A, Sansom, O, Greten, F, Wang, L, East, J, Tomlinson, I, Leedham, S