Editorial: New emerging functions of transcription factors and RNA-binding proteins in the development of hematological malignancies by Tarik Möröy, Tarik Möröy, Tarik Möröy, Cyrus Khandanpour

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The Role of Clonal Evolution on Progression, Blood Parameters, and Response to Therapy in Multiple Myeloma by Sarah Sandmann, Katharina Karsch, Peter Bartel, Rita Exeler, Tobias J. Brix, Elias K. Mai, Julian Varghese, Georg Lenz, Cyrus Khandanpour, Cyrus Khandanpour

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The RNA helicase DDX3 and its role in c-MYC driven germinal center-derived B-cell lymphoma by Marion Lacroix, Marion Lacroix, Hugues Beauchemin, Cyrus Khandanpour, Tarik Möröy, Tarik Möröy, Tarik Möröy

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Threshold Levels of Gfi1 Maintain E2A Activity for B Cell Commitment via Repression of Id1. by Jennifer Fraszczak, Anne Helness, Riyan Chen, Charles Vadnais, François Robert, Cyrus Khandanpour, Tarik Möröy

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Dose-dependent effect of GFI1 expression in the reconstitution and the differentiation capacity of HSCs by Xiaoqing Xie, Xiaoqing Xie, Pradeep Kumar Patnana, Pradeep Kumar Patnana, Pradeep Kumar Patnana, Daria Frank, Daria Frank, Judith Schütte, Judith Schütte, Yahya Al-Matary, Axel Künstner, Hauke Busch, Helal Ahmed, Helal Ahmed, Longlong Liu, Daniel R. Engel, Ulrich Dührsen, Frank Rosenbauer, Nikolas Von Bubnoff, Georg Lenz, Cyrus Khandanpour, Cyrus Khandanpour, Cyrus Khandanpour

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Combination Treatment Targeting mTOR and MAPK Pathways Has Synergistic Activity in Multiple Myeloma by Kaiyan Sun, Ling Jin, Jana Karolová, Jan Vorwerk, Stephan Hailfinger, Bertram Opalka, Myroslav Zapukhlyak, Georg Lenz, Cyrus Khandanpour

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Radiotherapy in Combination with Systemic Therapy for Multiple Myeloma—A Critical Toxicity Evaluation in the Modern Treatment Era by Michael Oertel, Tom Schlusemann, Evgenii Shumilov, Gabriele Reinartz, Anne Bremer, Stephan Rehn, Georg Lenz, Cyrus Khandanpour, Hans Theodor Eich

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Inhibiting PI3K–AKT–mTOR Signaling in Multiple Myeloma-Associated Mesenchymal Stem Cells Impedes the Proliferation of Multiple Myeloma Cells by Luca Heinemann, Klara Maria Möllers, Helal Mohammed Mohammed Ahmed, Lanying Wei, Kaiyan Sun, Subbaiah Chary Nimmagadda, Daria Frank, Anja Baumann, Anja Baumann, Alexandra M. Poos, Alexandra M. Poos, Martin Dugas, Julian Varghese, Marc-Steffen Raab, Marc-Steffen Raab, Cyrus Khandanpour, Cyrus Khandanpour

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P1005: EFFECT OF TL-895, A NOVEL BRUTON’S TYROSINE KINASE INHIBITOR (BTKI), ON ONCOGENIC JANUS KINASE 2-V617F (JAK2VF) SIGNALING by Subbaiah Chary Nimmagadda, Paulina Marie Budde, Kaiyan Sun, Todd Covey, Cecile Krejsa, Wayne P. Rothbaum, Nikolas von Bubnoff, Cyrus Khandanpour

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High Metabolic Dependence on Oxidative Phosphorylation Drives Sensitivity to Metformin Treatment in <i>MLL/AF9</i> Acute Myeloid Leukemia by Longlong Liu, Pradeep Kumar Patnana, Xiaoqing Xie, Daria Frank, Subbaiah Chary Nimmagadda, Annegret Rosemann, Marie Liebmann, Luisa Klotz, Bertram Opalka, Cyrus Khandanpour

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Presence of the GFI1-36N single nucleotide polymorphism enhances the response of MLL-AF9 leukemic cells to CDK4/6 inhibition by Jan Vorwerk, Kaiyan Sun, Daria Frank, Felix Neumann, Felix Neumann, Jana Hüve, Paulina Marie Budde, Longlong Liu, Xiaoqing Xie, Pradeep Kumar Patnana, Helal Mohammed Mohammed Ahmed, Bertram Opalka, Georg Lenz, Ashok Kumar Jayavelu, Ashok Kumar Jayavelu, Ashok Kumar Jayavelu, Ashok Kumar Jayavelu, Ashok Kumar Jayavelu, Cyrus Khandanpour, Cyrus Khandanpour

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Activity of tafasitamab in combination with rituximab in subtypes of aggressive lymphoma by Maria Patra-Kneuer, Gaomei Chang, Wendan Xu, Christian Augsberger, Michael Grau, Myroslav Zapukhlyak, Kristina Ilieva, Karin Landgraf, Doris Mangelberger-Eberl, Kasra Yousefi, Philipp Berning, Katrin S. Kurz, German Ott, Pavel Klener, Pavel Klener, Cyrus Khandanpour, Cyrus Khandanpour, Pedro Horna, Jürgen Schanzer, Stefan Steidl, Jan Endell, Christina Heitmüller, Georg Lenz

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Bcr-TMP, a Novel Nanomolar-Active Compound That Exhibits Both MYB- and Microtubule-Inhibitory Activity by Maria V. Yusenko, Abhiruchi Biyanee, Daria Frank, Leonhard H. F. Köhler, Mattias K. Andersson, Cyrus Khandanpour, Rainer Schobert, Göran Stenman, Bernhard Biersack, Karl-Heinz Klempnauer

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Curcumin as an Epigenetic Therapeutic Agent in Myelodysplastic Syndromes (MDS) by Xiaoqing Xie, Daria Frank, Pradeep Kumar Patnana, Judith Schütte, Yahya Al-Matary, Longlong Liu, Lanying Wei, Martin Dugas, Julian Varghese, Subbaiah Chary Nimmagadda, Cyrus Khandanpour

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GFI1 facilitates efficient DNA repair by regulating PRMT1 dependent methylation of MRE11 and 53BP1 by Charles Vadnais, Riyan Chen, Jennifer Fraszczak, Zhenbao Yu, Jonathan Boulais, Jordan Pinder, Daria Frank, Cyrus Khandanpour, Josée Hébert, Graham Dellaire, Jean-François Côté, Stéphane Richard, Alexandre Orthwein, Elliot Drobetsky, Tarik Möröy

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Daratumumab, Bortezomib, and Dexamethasone for Treatment of Patients with Relapsed or Refractory Multiple Myeloma and Severe Renal Impairment: Results from the Phase 2 GMMG-DANTE T... by Lisa B. Leypoldt, Maria Gavriatopoulou, Britta Besemer, Hans Salwender, Marc S. Raab, Axel Nogai, Cyrus Khandanpour, Volker Runde, Anna Jauch, Manola Zago, Peter Martus, Hartmut Goldschmidt, Carsten Bokemeyer, Meletios A. Dimopoulos, Katja C. Weisel

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Prevalence of the GFI1-36N SNP in Multiple Myeloma Patients and Its Impact on the Prognosis by Cyrus Khandanpour, Christine Eisfeld, Subbaiah Chary Nimmagadda, Marc S. Raab, Niels Weinhold, Anja Seckinger, Dirk Hose, Anna Jauch, Asta Försti, Asta Försti, Asta Försti, Kari Hemminki, Kari Hemminki, Thomas Hielscher, Manuela Hummel, Manuela Hummel, Georg Lenz, Hartmut Goldschmidt, Hartmut Goldschmidt, Stefanie Huhn

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High Frequencies of Anti-Host Reactive CD8+ T Cells Ignore Non-Hematopoietic Antigen after Bone Marrow Transplantation in a Murine Model by Asmae Gassa, Halime Kalkavan, Fu Jian, Vikas Duhan, Vishal Khairnar, Namir Shaabani, Nadine Honke, Alexander Carpinteiro, Lacramioara Botezatu, Pietro Crivello, Sebastian Dolff, Stanislav Ferencik, Dieter Häussinger, Cyrus Khandanpour, Katharina Fleischhauer, Oliver Witzke, Thorsten Wahlers, Cornelia Hardt, Philipp A. Lang, Karl S. Lang

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Characteristics and Outcome of Elderly Patients (>55 Years) with Acute Lymphoblastic Leukemia by Daniela V. Wenge, Klaus Wethmar, Corinna A. Klar, Hedwig Kolve, Tim Sauer, Linus Angenendt, Georg Evers, Simon Call, Andrea Kerkhoff, Cyrus Khandanpour, Torsten Kessler, Rolf Mesters, Christoph Schliemann, Jan-Henrik Mikesch, Christian Reicherts, Monika Brüggemann, Wolfgang E. Berdel, Georg Lenz, Matthias Stelljes

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Efficacy of COVID-19 Booster Vaccines in Patients with Hematologic Malignancies: Experiences in a Real-World Scenario by Carolin Krekeler, Lea Reitnauer, Ulrike Bacher, Cyrus Khandanpour, Leander Steger, Göran Ramin Boeckel, Justine Klosner, Phil-Robin Tepasse, Marcel Kemper, Marc Tim Hennies, Rolf Mesters, Matthias Stelljes, Norbert Schmitz, Andrea Kerkhoff, Christoph Schliemann, Jan-Henrik Mikesch, Nicole Schmidt, Georg Lenz, Annalen Bleckmann, Evgenii Shumilov

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