Molecular Footprints of the Immune Assault on Pancreatic Beta Cells in Type 1 Diabetes by Maikel L. Colli, Florian Szymczak, Decio L. Eizirik, Decio L. Eizirik, Decio L. Eizirik

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Beta Cell Imaging—From Pre-Clinical Validation to First in Man Testing by Stephane Demine, Michael L. Schulte, Paul R. Territo, Decio L. Eizirik

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Clic4, a novel protein that sensitizes β-cells to apoptosis by Dhaval Patel, Damien Ythier, Flora Brozzi, Decio L. Eizirik, Bernard Thorens

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JunB Inhibits ER Stress and Apoptosis in Pancreatic Beta Cells. by Esteban N Gurzov, Fernanda Ortis, Latifa Bakiri, Erwin F Wagner, Decio L Eizirik

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BCL-XL Overexpression Protects Pancreatic β-Cells against Cytokine- and Palmitate-Induced Apoptosis by Atenea A. Perez-Serna, Reinaldo S. Dos Santos, Cristina Ripoll, Angel Nadal, Decio L. Eizirik, Laura Marroqui

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The transcription factor C/EBP delta has anti-apoptotic and anti-inflammatory roles in pancreatic beta cells. by Fabrice Moore, Izortze Santin, Tatiane C Nogueira, Esteban N Gurzov, Lorella Marselli, Piero Marchetti, Decio L Eizirik

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Mining the transcriptome of target tissues of autoimmune and degenerative pancreatic β-cell and brain diseases to discover therapies by Xiaoyan Yi, Bianca Marmontel de Souza, Toshiaki Sawatani, Florian Szymczak, Lorella Marselli, Piero Marchetti, Miriam Cnop, Decio L. Eizirik

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A Humanized Mouse Strain That Develops Spontaneously Immune-Mediated Diabetes by Sandrine Luce, Sandrine Luce, Sophie Guinoiseau, Sophie Guinoiseau, Alexis Gadault, Alexis Gadault, Franck Letourneur, Patrick Nitschke, Marc Bras, Michel Vidaud, Pierre Charneau, Etienne Larger, Etienne Larger, Maikel L. Colli, Decio L. Eizirik, Decio L. Eizirik, François Lemonnier, François Lemonnier, Christian Boitard, Christian Boitard, Christian Boitard

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Pancreatic α Cells are Resistant to Metabolic Stress-induced Apoptosis in Type 2 Diabetes by Laura Marroqui, Matilde Masini, Beatriz Merino, Fabio A. Grieco, Isabelle Millard, Christine Dubois, Ivan Quesada, Piero Marchetti, Miriam Cnop, Decio L. Eizirik

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The Role of Beta Cell Recovery in Type 2 Diabetes Remission by Mara Suleiman, Lorella Marselli, Miriam Cnop, Decio L. Eizirik, Carmela De Luca, Francesca R. Femia, Marta Tesi, Silvia Del Guerra, Piero Marchetti

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Pro-Inflammatory Cytokines Promote the Transcription of Circular RNAs in Human Pancreatic β Cells by Simranjeet Kaur, Caroline Frørup, Aashiq H. Mirza, Tina Fløyel, Reza Yarani, Maikel L. Colli, Jesper Johannesen, Joachim Størling, Decio L. Eizirik, Flemming Pociot

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SARS-CoV-2 Receptor Angiotensin I-Converting Enzyme Type 2 (ACE2) Is Expressed in Human Pancreatic β-Cells and in the Human Pancreas Microvasculature by Daniela Fignani, Daniela Fignani, Giada Licata, Giada Licata, Noemi Brusco, Noemi Brusco, Laura Nigi, Laura Nigi, Giuseppina E. Grieco, Giuseppina E. Grieco, Lorella Marselli, Lut Overbergh, Conny Gysemans, Maikel L. Colli, Piero Marchetti, Chantal Mathieu, Decio L. Eizirik, Decio L. Eizirik, Guido Sebastiani, Guido Sebastiani, Francesco Dotta, Francesco Dotta, Francesco Dotta

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Differential cell autonomous responses determine the outcome of coxsackievirus infections in murine pancreatic α and β cells by Laura Marroqui, Miguel Lopes, Reinaldo S dos Santos, Fabio A Grieco, Merja Roivainen, Sarah J Richardson, Noel G Morgan, Anne Op de beeck, Decio L Eizirik

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Exposure to the viral by-product dsRNA or Coxsackievirus B5 triggers pancreatic beta cell apoptosis via a Bim / Mcl-1 imbalance. by Maikel L Colli, Tatiane C Nogueira, Florent Allagnat, Daniel A Cunha, Esteban N Gurzov, Alessandra K Cardozo, Merja Roivainen, Anne Op de Beeck, Decio L Eizirik

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GLIS3, a susceptibility gene for type 1 and type 2 diabetes, modulates pancreatic beta cell apoptosis via regulation of a splice variant of the BH3-only protein Bim. by Tatiane C Nogueira, Flavia M Paula, Olatz Villate, Maikel L Colli, Rodrigo F Moura, Daniel A Cunha, Lorella Marselli, Piero Marchetti, Miriam Cnop, Cécile Julier, Decio L Eizirik

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The lipid sensor GPR120 promotes brown fat activation and FGF21 release from adipocytes by Tania Quesada-López, Rubén Cereijo, Jean-Valery Turatsinze, Anna Planavila, Montserrat Cairó, Aleix Gavaldà-Navarro, Marion Peyrou, Ricardo Moure, Roser Iglesias, Marta Giralt, Decio L. Eizirik, Francesc Villarroya

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Pro-Inflammatory Cytokines Induce Insulin and Glucagon Double Positive Human Islet Cells That Are Resistant to Apoptosis by Marta Tesi, Marco Bugliani, Gianmarco Ferri, Mara Suleiman, Carmela De Luca, Emanuele Bosi, Matilde Masini, Vincenzo De Tata, Conny Gysemans, Francesco Cardarelli, Miriam Cnop, Decio L. Eizirik, Piero Marchetti, Lorella Marselli

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Combined transcriptome and proteome profiling of the pancreatic β-cell response to palmitate unveils key pathways of β-cell lipotoxicity by Maria Lytrivi, Kassem Ghaddar, Miguel Lopes, Victoria Rosengren, Anthony Piron, Xiaoyan Yi, Henrik Johansson, Janne Lehtiö, Mariana Igoillo-Esteve, Daniel A. Cunha, Lorella Marselli, Piero Marchetti, Henrik Ortsäter, Decio L. Eizirik, Miriam Cnop

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The Protective Action of Metformin against Pro-Inflammatory Cytokine-Induced Human Islet Cell Damage and the Mechanisms Involved by Laura Giusti, Marta Tesi, Federica Ciregia, Lorella Marselli, Lorenzo Zallocco, Mara Suleiman, Carmela De Luca, Silvia Del Guerra, Mariachiara Zuccarini, Marco Trerotola, Decio L. Eizirik, Miriam Cnop, Maria R. Mazzoni, Piero Marchetti, Antonio Lucacchini, Maurizio Ronci

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Vitamin D3 Induces Tolerance in Human Dendritic Cells by Activation of Intracellular Metabolic Pathways by Gabriela Bomfim Ferreira, An-Sofie Vanherwegen, Guy Eelen, Ana Carolina Fierro Gutiérrez, Leentje Van Lommel, Kathleen Marchal, Lieve Verlinden, Annemieke Verstuyf, Tatiane Nogueira, Maria Georgiadou, Frans Schuit, Décio L. Eizirik, Conny Gysemans, Peter Carmeliet, Lut Overbergh, Chantal Mathieu

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