Discovery of novel immunopharmacological ligands targeting the IL-17 inflammatory pathway by Álvarez-Coiradas, E, Munteanu, CR, Díaz-Sáez, L, Pazos, A, Huber, KVM, Loza, MI, Domínguez, E

Re-evaluating the mechanism of action of α,β-unsaturated carbonyl DUB inhibitors b-AP15 and VLX1570: a paradigmatic example of unspecific protein crosslinking with Michael acceptor... by Ward, JA, Pinto-Fernandez, A, Cornelissen, L, Bonham, S, Díaz-Sáez, L, Riant, O, Huber, KVM, Kessler, BM, Feron, O, Tate, EW

Re-evaluating the mechanism of action of α,β-unsaturated carbonyl DUB inhibitors B-AP15 and VLX1570: a paradigmatic example of unspecific protein crosslinking with Michael acceptor... by Ward, J, Pinto-Fernandez, A, Cornelissen, L, Bonham, S, Diaz Saez, L, Riant, O, Huber, K, Kessler, B, Feron, O, Tate, E

Fragment screening reveals starting points for rational design of galactokinase 1 inhibitors to treat classic galactosemia by Mackinnon, SR, Krojer, T, Foster, WR, Diaz-Saez, L, Tang, M, Huber, KVM, von Delft, F, Lai, K, Brennan, PE, Arruda Bezerra, G, Yue, WW

Deliberately losing control of C-H activation processes in the design of small-molecule-fragment arrays targeting peroxisomal metabolism by Kahn Tareque, R, Hassell-Hart, S, Krojer, T, Bradley, A, Velupillai, S, Talon, R, Fairhead, M, Day, IJ, Bala, K, Felix, R, Kemmitt, P, Brennan, P, von Delft, F, Díaz Sáez, L, Spencer, J, Huber, K

Benzoisoquinolinediones as potent and selective inhibitors of BRPF2 and TAF1/TAF1L bromodomains by Bouché, L, Christ, C, Siegel, S, Fernández-Montalván, A, Holton, S, Fedorov, O, Ter Laak, A, Sugawara, T, Stöckigt, D, Tallant, C, Bennett, J, Monteiro, O, Díaz-Sáez, L, Siejka, P, Meier, J, Pütter, V, Weiske, J, Müller, S, Huber, K, Hartung, I, Haendler, B

Creation of a novel class of potent and selective MutT Homologue 1 (MTH1) inhibitors using fragment-based screening and structure-based drug design by Rahm, F, Viklund, J, Trésaugues, L, Ellermann, M, Giese, A, Ericsson, U, Forsblom, R, Ginman, T, Günther, J, Hallberg, K, Lindström, J, Persson, L, Silvander, C, Talagas, A, Díaz-Sáez, L, Fedorov, O, Huber, K, Panagakou, I, Siejka, P, Gorjánácz, M, Bauser, M, Andersson, M

Deletion of the deISGylating enzyme USP18 enhances tumour cell antigenicity and radiosensitivity by Pinto-Fernandez, A, Salio, M, Partridge, T, Chen, J, Vere, G, Greenwood, H, Olie, CS, Damianou, A, Scott, HC, Pegg, J, Chiarenza, A, Diaz-Saez, L, Smith, P, Gonzalez-Lopez, C, Patel, B, Jones, N, Hammonds, T, Huber, K, Muschel, R, Borrow, P, Cerundolo, V, Kessler, B

Isoform-selective ATAD2 chemical probe with novel chemical structure and unusual mode of action by Fernández-Montalván, A, Berger, M, Kuropka, B, Koo, S, Badock, V, Weiske, J, Puetter, V, Holton, S, Stöckigt, D, Ter Laak, A, Centrella, P, Clark, M, Dumelin, C, Sigel, E, Soutter, H, Troast, D, Zhang, Y, Cuozzo, J, Keefe, A, Roche, D, Rodeschini, V, Chaikuad, A, Díaz-Sáez, L, Bennett, J, Fedorov, O, Huber, K, Hübner, J, Weinmann, H, Hartung, I, Gorjánácz, M

Rapid covalent-probe discovery by electrophile-fragment screening by Resnick, E, Bradley, A, Gan, J, Douangamath, A, Krojer, T, Sethi, R, Geurink, PP, Aimon, A, Amitai, G, Bellini, D, Bennett, J, Fairhead, M, Fedorov, O, Gabizon, R, Gan, J, Guo, J, Plotnikov, A, Reznik, N, Ruda, GF, Díaz-Sáez, L, Straub, VM, Szommer, T, Velupillai, S, Zaidman, D, Zhang, Y, Coker, AR, Dowson, CG, Barr, HM, Wang, C, Huber, KVM, Brennan, PE, Ovaa, H, Von Delft, F, London, N