Mark Daly (scientist)
Mark Joseph Daly is Director of the Finnish Institute for Molecular Medicine (FIMM) at the University of Helsinki, a Professor of Genetics at Harvard Medical School, Chief of the Analytic and Translational Genetic Unit at Massachusetts General Hospital, and a member of the Broad Institute of MIT and Harvard. In the early days of the Human Genome Project, Daly helped develop the genetic model by which linkage disequilibrium could be used to map the haplotype structure of the human genome. In addition, he developed statistical methods to find associations between genes and disorders such as Crohn's disease, inflammatory bowel disease, autism and schizophrenia.Daly is considered a pioneer in the field of human genetics, and is amongst the most cited scientists in the field, and one of the top 100 most cited scientists of all time. He was elected to the National Academy of Medicine in 2017. Provided by Wikipedia
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Host genetic variation and its microbiome interactions within the Human Microbiome Project by Kolde, Raivo, Rahnavard, Gholamali, Vlamakis, Hera, Stevens, Christine, Huttenhower, Curtis, Franzosa, Eric A., Hall, Andrew Brantley, Daly, Mark J., Xavier, Ramnik Joseph
Published 2018
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Quantifying unobserved protein-coding variants in human populations provides a roadmap for large-scale sequencing projects by Zou, James, Valiant, Gregory, Valiant, Paul, Karczewski, Konrad, Chan, Siu On, Samocha, Kaitlin, Lek, Monkol, MacArthur, Daniel G., Sunyaev, Shamil R., Daly, Mark J.
Published 2017
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Proteins encoded in genomic regions associated with immune-mediated disease physically interact and suggest underlying biology by Rossin, Elizabeth, Lage, Kasper, Raychaudhuri, Soumya, Xavier, Ramnik J., Tatar, Diana, Benita, Yair, International Inflammatory Bowel Disease Genetics Constortium, Cotsapas, Chris, Daly, Mark J.
Published 2011
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Identifying relationships among genomic disease regions: predicting= pathogenic SNP associations and rare deletions by Raychaudhuri, Soumya, Plenge, Robert M., Rossin, Elizabeth, Ng, Aylwin C. Y., Purcell, Shaun M., Sklar, Pamela, Scolnick, Edward Mark, Xavier, Ramnik J., Altshuler, David, Daly, Mark J.
Published 2010
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The Genome Analysis Toolkit: A MapReduce framework for analyzing next-generation DNA sequencing data by McKenna, Aaron, Hanna, Matthew, Sivachenko, Andrey, Cibulskis, Kristian, Kernytsky, Andrew, Garimella, Kiran, Altshuler, David, Gabriel, Stacey B., Daly, Mark J., DePristo, Mark A., Banks, Eric, 1976-
Published 2014
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Identifying Relationships among Genomic Disease Regions: Predicting Genes at Pathogenic SNP Associations and Rare Deletions by Daly, Mark J., Altshuler, David, Xavier, Ramnik J., Sklar, Pamela, Purcell, Shaun M., International Schizophrenia Consortium, Ng, Aylwin C. Y., Scolnick, Edward Mark, Rossin, Elizabeth, Plenge, Robert M., Raychaudhuri, Soumya
Published 2010
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Mutations in ATP13A2 (PARK9) are associated with an amyotrophic lateral sclerosis-like phenotype, implicating this locus in further phenotypic expansion by Spataro, Rossella, Kousi, Maria, Farhan, Sali M K, Willer, Jason R, Ross, Jay P, Dion, Patrick A, Rouleau, Guy A, Daly, Mark J, Neale, Benjamin M, La Bella, Vincenzo, Katsanis, Nicholas
Published 2020
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Genetic resistance to diet-induced obesity in chromosome substitution strains of mice by Burrage, Lindsay C., Baskin-Hill, Annie E., Sinasac, David S., Singer, Jonathan B., Croniger, Colleen M., Kirby, Andrew, Kulbokas, E. J., Daly, Mark J., Broman, Karl W., Nadeau, Joseph H., Lander, Eric Steven
Published 2014
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A global reference for human genetic variation by The 1000 Genomes Project Consortium, Gabriel, Stacey, Lander, Eric Steven, Banks, Eric, Bhatia, Gaurav, Kashin, Seva, McCarroll, Steven A, Nemesh, James, Poplin, Ryan E., Sabeti, Pardis, Shlyakhter, Ilya, Schaffner, Stephen F, Vitti, Joseph, Hartler, Christina M., Tariyal, Ridhi, Daly, Mark J., Gymrek, Melissa A.
Published 2017
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TMEM258 Is a Component of the Oligosaccharyltransferase Complex Controlling ER Stress and Intestinal Inflammation by Graham, Daniel B., Lefkovith, Ariel, Deelen, Patrick, de Klein, Niek, Boroughs, Angela, Desch, A. Nicole, Ng, Aylwin C.Y., Petersen, Christine P., Bhan, Atul K., Wijmenga, Cisca, Varma, Mukund Madhav, Guzman, Gaelen Donnelly, Schenone, Monica, Rivas, Manuel A, Carr, Steven A, Xavier, Ramnik Joseph, Daly, Mark J.
Published 2017
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Survey of variation in human transcription factors reveals prevalent DNA binding changes by Vedenko, A., Kurland, J. V., Rogers, J. M., Gisselbrecht, S. S., Woodard, J., Mariani, L., Kock, K. H., Inukai, S., Siggers, T., Shokri, L., Gordan, R., Sahni, N., Cotsapas, C., Hao, T., Yi, S., Vidal, M., Hill, D. E., Barrera, Luis Alberto, Rossin, Elizabeth, Kellis, Manolis, Daly, Mark J., Bulyk, Martha L.
Published 2017
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Pervasive Sharing of Genetic Effects in Autoimmune Disease by Cotsapas, Chris, Voight, Benjamin F., Lage, Kasper, Neale, Benjamin M., Wallace, Chris, Abecasis, Gonçalo R., Barrett, Jeffrey C., Behrens, Timothy, Cho, Judy, Jager, Philip L. De, Elder, James T., Graham, Robert R., Gregersen, Peter K., Klareskog, Lars, Siminovitch, Katherine A., Heel, David A. van, Wijmenga, Cisca, Worthington, Jane, Todd, John A., Hafler, David A., Rich, Stephen S., Daly, Mark J., Rossin, Elizabeth
Published 2012
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Fine mapping of type 1 diabetes susceptibility loci and evidence for colocalization of causal variants with lymphoid gene enhancers by Onengut-Gumuscu, Suna, Chen, Wei-Min, Burren, Oliver, Farber, Emily, Szpak, Michal, Schofield, Ellen, Achuthan, Premanand, Guo, Hui, Stevens, Helen, Kundaje, Anshul, Kellis, Manolis, Deloukas, Panos, Wallace, Chris, Concannon, Patrick, Cooper, Nick J., Quinlan, Aaron R., Mychaleckyj, Josyf C., Bonnie, Jessica K., Fortune, Mary D., Walker, Neil M., Ward, Lucas D., Daly, Mark J., Barrett, Jeffrey C., Cooper, Jason D., Todd, John A., Rich, Stephen S.
Published 2016
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Atg16L1 T300A variant decreases selective autophagy resulting in altered cytokine signaling and decreased antibacterial defense by Lassen, Kara G., Kuballa, Petric, Conway, Kara L., Patel, Khushbu, Becker, Christine E., Peloquin, Joanna M., Villablanca, Eduardo J., Norman, Jason M., Liu, Ta-Chung, Heath, Robert J. W., Becker, Morgan L., Fagbami, Lola, Horn, Heiko, Mercer, Johnathan, Yilmaz, Omer, Jaffe, Jacob D., Shamji, Alykhan F., Bahn, Atul K., Carr, Steven A., Daly, Mark J., Virgin, Herbert W., Schreiber, Stuart L., Stappenbeck, Thaddeus S., Xavier, Ramnik J.
Published 2014
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Genome-Wide Association Studies in an Isolated Founder Population from the Pacific Island of Kosrae by Lowe, Jennifer K., Maller, Julian B., Pe'er, Itsik, Neale, Benjamin M., Salit, Jacqueline, Kenny, Eimear E., Shea, Jessica L., Burkhardt, Ralph, Smith, J. Gustav, Ji, Weizhen, Noel, Martha, Foo, Jia Nee, Blundell, Maude L., Skilling, Vita, Garcia, Laura, Sullivan, Marcia L., Lee, Heather E., Labek, Anna, Ferdowsian, Hope, Auerbach, Steven B., Lifton, Richard P., Newton-Cheh, Christopher, Breslow, Jan L., Stoffel, Markus, Daly, Mark J., Altshuler, David, Friedman, Jeffrey M.
Published 2014
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The role of the CD[subscript 5]8 locus in multiple sclerosis by De Jager, Philip L., Baecher-Allan, Clare, Maier, Lisa M., Arthur, Ariel T., Ottoboni, Linda, Barcellos, Lisa F., McCauley, Jacob L., Sawcer, Stephen, Goris, An, Saarela, Janna, Yelensky, Roman, Price, Alkes, Leppa, Virpi, Patterson, Nick, de Bakker, Paul I. W., Tran, Dong, Aubin, Cristin, Pobywajlo, Susan, Rossin, Elizabeth, Hu, Xinli, Ashley, Charles W., Choy, Edwin, Rioux, John D., Pericak-Vance, Margaret A., Ivinson, Adrian, Booth, David R., Stewart, Graeme J., Palotie, Aarno, Peltonen, Leena, Dubois, Benedicte, Haines, Jonathan L., Weiner, Howard L., Compston, Alastair, Hauser, Stephen L., Daly, Mark J., Reich, David, Oksenberg, Jorge R., Hafler, David A.
Published 2009
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