Iron is a specific cofactor for distinct oxidation- and aggregation-dependent Aβ toxicity mechanisms in a Drosophila model by Stanislav Ott, Nikolas Dziadulewicz, Damian C. Crowther

Get full text

Central and peripheral circadian clocks and their role in Alzheimer's disease by Ruchi Chauhan, Ko-Fan Chen, Brianne A. Kent, Damian C. Crowther

Get full text

The central molecular clock is robust in the face of behavioural arrhythmia in a Drosophila model of Alzheimer’s disease by Ko-Fan Chen, Bernard Possidente, David A. Lomas, Damian C. Crowther

Get full text

The TRiC/CCT chaperone is implicated in Alzheimer's disease based on patient GWAS and an RNAi screen in Aβ-expressing Caenorhabditis elegans. by Eleonora Khabirova, Aileen Moloney, Stefan J Marciniak, Julie Williams, David A Lomas, Stephen G Oliver, Giorgio Favrin, David B Sattelle, Damian C Crowther

Get full text

CCT complex restricts neuropathogenic protein aggregation via autophagy by Mariana Pavel, Sara Imarisio, Fiona M. Menzies, Maria Jimenez-Sanchez, Farah H. Siddiqi, Xiaoting Wu, Maurizio Renna, Cahir J. O’Kane, Damian C. Crowther, David C. Rubinsztein

Get full text

Systematic in vivo analysis of the intrinsic determinants of amyloid Beta pathogenicity. by Leila M Luheshi, Gian Gaetano Tartaglia, Ann-Christin Brorsson, Amol P Pawar, Ian E Watson, Fabrizio Chiti, Michele Vendruscolo, David A Lomas, Christopher M Dobson, Damian C Crowther

Get full text

Sequestration of the Abeta peptide prevents toxicity and promotes degradation in vivo. by Leila M Luheshi, Wolfgang Hoyer, Teresa Pereira de Barros, Iris van Dijk Härd, Ann-Christin Brorsson, Bertil Macao, Cecilia Persson, Damian C Crowther, David A Lomas, Stefan Ståhl, Christopher M Dobson, Torleif Härd

Get full text