AmpliconDesign – an interactive web server for the design of high-throughput targeted DNA methylation assays by Maximilian Schönung, Jana Hess, Pascal Bawidamann, Sina Stäble, Joschka Hey, Jens Langstein, Yassen Assenov, Dieter Weichenhan, Pavlo Lutsik, Daniel B. Lipka

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Effects of Label Noise on Deep Learning-Based Skin Cancer Classification by Achim Hekler, Jakob N. Kather, Jakob N. Kather, Eva Krieghoff-Henning, Jochen S. Utikal, Jochen S. Utikal, Friedegund Meier, Friedegund Meier, Frank F. Gellrich, Frank F. Gellrich, Julius Upmeier zu Belzen, Lars French, Justin G. Schlager, Kamran Ghoreschi, Tabea Wilhelm, Heinz Kutzner, Carola Berking, Markus V. Heppt, Sebastian Haferkamp, Wiebke Sondermann, Dirk Schadendorf, Bastian Schilling, Benjamin Izar, Roman Maron, Max Schmitt, Stefan Fröhling, Stefan Fröhling, Daniel B. Lipka, Daniel B. Lipka, Daniel B. Lipka, Titus J. Brinker

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Intracellular retention of ABL kinase inhibitors determines commitment to apoptosis in CML cells. by Daniel B Lipka, Marie-Christine Wagner, Marek Dziadosz, Tina Schnöder, Florian Heidel, Mirle Schemionek, Junia V Melo, Thomas Kindler, Carsten Müller-Tidow, Steffen Koschmieder, Thomas Fischer

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Differential roles of STAT1 and STAT2 in the sensitivity of JAK2V617F- vs. BCR-ABL-positive cells to interferon alpha by Claudia Schubert, Manuel Allhoff, Stefan Tillmann, Tiago Maié, Ivan G. Costa, Daniel B. Lipka, Mirle Schemionek, Kristina Feldberg, Julian Baumeister, Tim H. Brümmendorf, Nicolas Chatain, Steffen Koschmieder

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Bisulfite-free epigenomics and genomics of single cells through methylation-sensitive restriction by Christoph Niemöller, Julius Wehrle, Julian Riba, Rainer Claus, Nathalie Renz, Janika Rhein, Sabine Bleul, Juliane M. Stosch, Justus Duyster, Christoph Plass, Pavlo Lutsik, Daniel B. Lipka, Michael Lübbert, Heiko Becker

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Genome-wide DNA methylation is predictive of outcome in juvenile myelomonocytic leukemia by Elliot Stieglitz, Tali Mazor, Adam B. Olshen, Huimin Geng, Laura C. Gelston, Jon Akutagawa, Daniel B. Lipka, Christoph Plass, Christian Flotho, Farid F. Chehab, Benjamin S. Braun, Joseph F. Costello, Mignon L. Loh

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S122: MUTANT IDH1 HIJACKS DIFFERENTIATION PROGRAMS IN MYELOID PROGENITOR CELLS TO IMPAIR GRANULOCYTIC DIFFERENTIATION. by Mariam Hakobyan, Jens Langstein, Emely Kleinert, Maximilian Schönung, Mark Hartmann, Hannah Rohdjess, Sina Staeble, Rainer Claus, Lars Bullinger, Christopher Oakes, Karsten Rippe, Stefan Fröhling, Stefan Pusch, Christoph Plass, Michael Milsom, Daniel B. Lipka

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A Phase Ib Dose-finding Study of Panobinostat and Ruxolitinib in Myelofibrosis by Claire Harrison, Florian H. Heidel, Alessandro M. Vannucchi, Jean-Jacques Kiladjian, Amjad Hayat, Francesco Passamonti, Eibhlin Conneally, Thomas Kindler, Bruno Martino, Daniel B. Lipka, Tommaso Stefanelli, Pantelia Roussou, Davide Germano, Jacqueline Ewan, Vincent Ribrag

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The antileukemic activity of decitabine upon PML/RARA-negative AML blasts is supported by all-trans retinoic acid: in vitro and in vivo evidence for cooperation by Ruth Meier, Gabriele Greve, Dennis Zimmer, Helena Bresser, Bettina Berberich, Ralitsa Langova, Julia Stomper, Anne Rubarth, Lars Feuerbach, Daniel B. Lipka, Joschka Hey, Björn Grüning, Benedikt Brors, Justus Duyster, Christoph Plass, Heiko Becker, Michael Lübbert

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LaminA/C regulates epigenetic and chromatin architecture changes upon aging of hematopoietic stem cells by Ani Grigoryan, Novella Guidi, Katharina Senger, Thomas Liehr, Karin Soller, Gina Marka, Angelika Vollmer, Yolanda Markaki, Heinrich Leonhardt, Christian Buske, Daniel B. Lipka, Christoph Plass, Yi Zheng, Medhanie A. Mulaw, Hartmut Geiger, Maria Carolina Florian

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Identification of Cell Type-Specific Differences in Erythropoietin Receptor Signaling in Primary Erythroid and Lung Cancer Cells. by Ruth Merkle, Bernhard Steiert, Florian Salopiata, Sofia Depner, Andreas Raue, Nao Iwamoto, Max Schelker, Helge Hass, Marvin Wäsch, Martin E Böhm, Oliver Mücke, Daniel B Lipka, Christoph Plass, Wolf D Lehmann, Clemens Kreutz, Jens Timmer, Marcel Schilling, Ursula Klingmüller

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Clinically relevant doses of FLT3-kinase inhibitors quizartinib and midostaurin do not impair T-cell reactivity and function by Denise Wolleschak, Thomas S. Mack, Florian Perner, Stephanie Frey, Tina M. Schnöder, Marie-Christine Wagner, Christine Höding, Marina C. Pils, Andreas Parkner, Stefanie Kliche, Burkhart Schraven, Katrin Hebel, Monika Brunner-Weinzierl, Satish Ranjan, Berend Isermann, Daniel B. Lipka, Thomas Fischer, Florian H. Heidel

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Methylome-based cell-of-origin modeling (Methyl-COOM) identifies aberrant expression of immune regulatory molecules in CLL by Justyna A. Wierzbinska, Reka Toth, Naveed Ishaque, Karsten Rippe, Jan-Philipp Mallm, Lara C. Klett, Daniel Mertens, Thorsten Zenz, Thomas Hielscher, Marc Seifert, Ralf Küppers, Yassen Assenov, Pavlo Lutsik, Stephan Stilgenbauer, Philipp M. Roessner, Martina Seiffert, John Byrd, Christopher C. Oakes, Christoph Plass, Daniel B. Lipka

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Neutrophil-specific expression of JAK2-V617F or CALRmut induces distinct inflammatory profiles in myeloproliferative neoplasia by Tobias Ronny Haage, Emmanouil Charakopoulos, Vikas Bhuria, Conny K. Baldauf, Mark Korthals, Juliane Handschuh, Peter Müller, Juan Li, Kunjan Harit, Gopala Nishanth, Stephanie Frey, Martin Böttcher, Klaus-Dieter Fischer, Jan Dudeck, Anne Dudeck, Daniel B. Lipka, Burkhart Schraven, Anthony R. Green, Andreas J. Müller, Dimitrios Mougiakakos, Thomas Fischer

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Integrating Patient Data Into Skin Cancer Classification Using Convolutional Neural Networks: Systematic Review by Julia Höhn, Achim Hekler, Eva Krieghoff-Henning, Jakob Nikolas Kather, Jochen Sven Utikal, Friedegund Meier, Frank Friedrich Gellrich, Axel Hauschild, Lars French, Justin Gabriel Schlager, Kamran Ghoreschi, Tabea Wilhelm, Heinz Kutzner, Markus Heppt, Sebastian Haferkamp, Wiebke Sondermann, Dirk Schadendorf, Bastian Schilling, Roman C Maron, Max Schmitt, Tanja Jutzi, Stefan Fröhling, Daniel B Lipka, Titus Josef Brinker

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Molecular Characterization and Clinical Relevance of MGMT‐Silenced Pancreatic Cancer by Federico Nichetti, Marco Silvestri, Luca Agnelli, Andrea Franza, Chiara Pircher, Simone Rota, Paolo Ambrosini, Giuseppe Fotia, Jennifer Hüllein, Giovanni Randon, Panna Lajer, Federica Perrone, Elena Tamborini, Giuseppe Leoncini, Jorgelina Coppa, Michele Droz Dit Busset, Sara Pusceddu, Massimo Milione, Federica Morano, Filippo Pietrantonio, Giancarlo Pruneri, Vincenzo Mazzaferro, Daniel B. Lipka, Bruno Christian Köhler, Daniel Hübschmann, Stefan Fröhling, Filippo deBraud, Monica Niger

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S120: MNX1-ACTIVATING ENHANCER HIJACKING EVENTS IN ACUTE MYELOID LEUKEMIA WITH DELETIONS ON CHROMOSOME 7Q by Anna Riedel, Justyna A. Wierzbińska, Umut H. Toprak, Aurore Touzart, Etienne Sollier, Simge Kelekçi, Katherine Kelly, Dieter Weichenhan, Anastasija Pejkovska, Ashish Goyal, Charlotte Meinen, Matthias Schlesner, Frank Westermann, Benedikt Brors, Lars Bullinger, Philipp Greif, Michael Lübbert, Florian Heidel, Thomas Fischer, Claudia Gebhard, Brigitte Schlegelberger, Gudrun Göhring, Yvonne Behrens, Ekaterina Jahn, Hartmut Döhner, Konstanze Döhner, Ruud Delwel, Pavlo Lutsik, Daniel B. Lipka, Christoph Plass

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Control of APOBEC3B induction and cccDNA decay by NF-κB and miR-138-5p by Suzanne Faure-Dupuy, Tobias Riedl, Maude Rolland, Zoheir Hizir, Florian Reisinger, Katharina Neuhaus, Svenja Schuehle, Caroline Remouchamps, Nicolas Gillet, Maximilian Schönung, Mira Stadler, Jochen Wettengel, Romain Barnault, Romain Parent, Linda Christina Schuster, Rayan Farhat, Sandra Prokosch, Corinna Leuchtenberger, Rupert Öllinger, Thomas Engleitner, Karsten Rippe, Roland Rad, Kristian Unger, Darjus Tscharahganeh, Daniel B. Lipka, Ulrike Protzer, David Durantel, Julie Lucifora, Emmanuel Dejardin, Mathias Heikenwälder

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Multi-omic and functional analysis for classification and treatment of sarcomas with FUS-TFCP2 or EWSR1-TFCP2 fusions by Julia Schöpf, Sebastian Uhrig, Christoph E. Heilig, Kwang-Seok Lee, Tatjana Walther, Alexander Carazzato, Anna Maria Dobberkau, Dieter Weichenhan, Christoph Plass, Mark Hartmann, Gaurav D. Diwan, Zunamys I. Carrero, Claudia R. Ball, Tobias Hohl, Thomas Kindler, Patricia Rudolph-Hähnel, Dominic Helm, Martin Schneider, Anna Nilsson, Ingrid Øra, Roland Imle, Ana Banito, Robert B. Russell, Barbara C. Jones, Daniel B. Lipka, Hanno Glimm, Daniel Hübschmann, Wolfgang Hartmann, Stefan Fröhling, Claudia Scholl

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MGMT inactivation as a new biomarker in patients with advanced biliary tract cancers by Monica Niger, Federico Nichetti, Andrea Casadei‐Gardini, Federica Morano, Chiara Pircher, Elena Tamborini, Federica Perrone, Matteo Canale, Daniel B. Lipka, Andrea Vingiani, Luca Agnelli, Anna Dobberkau, Jennifer Hüllein, Felix Korell, Christoph E. Heilig, Sara Pusceddu, Francesca Corti, Michele Droz, Paola Ulivi, Michele Prisciandaro, Maria Antista, Marta Bini, Laura Cattaneo, Massimo Milione, Hanno Glimm, Bruno C. Köhler, Giancarlo Pruneri, Daniel Hübschmann, Stefan Fröhling, Vincenzo Mazzaferro, Filippo Pietrantonio, Maria Di Bartolomeo, Filippo deBraud

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