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Danielle Posthuma

Danielle Posthuma is a Dutch behavior and psychiatric geneticist who specializes in statistical genetics. She is a University Research Chair professor at VU University Amsterdam, where she is also head of the Department of Complex Trait Genetics. She has been a member of the Young Academy of the Royal Dutch Academy of Sciences since 2005. She is known for studying the genetics of psychiatric and cognitive traits, including schizophrenia, neuroticism, Alzheimer's disease, insomnia, as well as genetics of intelligence, which she first became interested in researching in the 1990s. In 2019 Posthuma became a member of the Royal Netherlands Academy of Arts and Sciences. Provided by Wikipedia

1

Genetically-Informed Patient Selection for iPSC Studies of Complex Diseases May Aid in Reducing Cellular Heterogeneity by Stephanie D. Hoekstra, Sven Stringer, Vivi M. Heine, Vivi M. Heine, Danielle Posthuma, Danielle Posthuma

Published 2017-06-01

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2

Genome-wide association studies of polygenic risk score-derived phenotypes may lead to inflated false positive rates by Emil Uffelmann, Danielle Posthuma, Wouter J. Peyrot

Published 2023-03-01

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3

TATES: efficient multivariate genotype-phenotype analysis for genome-wide association studies. by Sophie van der Sluis, Danielle Posthuma, Conor V Dolan

Published 2013-01-01

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4

Phenotypic complexity, measurement bias, and poor phenotypic resolution contribute to the missing heritability problem in genetic association studies. by Sophie van der Sluis, Matthijs Verhage, Danielle Posthuma, Conor V Dolan

Published 2010-11-01

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5

MAGMA: generalized gene-set analysis of GWAS data. by Christiaan A de Leeuw, Joris M Mooij, Tom Heskes, Danielle Posthuma

Published 2015-04-01

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6

Correction: Genome-wide gene-environment interactions in neuroticism: an exploratory study across 25 environments by Josefin Werme, Sophie van der Sluis, Danielle Posthuma, Christiaan A. de Leeuw

Published 2022-05-01

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Article
7

Correction to: Genome-wide gene-environment interactions in neuroticism: an exploratory study across 25 environments by Josefin Werme, Sophie van der Sluis, Danielle Posthuma, Christiaan A. de Leeuw

Published 2021-04-01

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Article
8

Item-level analyses reveal genetic heterogeneity in neuroticism by Mats Nagel, Kyoko Watanabe, Sven Stringer, Danielle Posthuma, Sophie van der Sluis

Published 2018-03-01

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9

Genome-wide gene-environment interactions in neuroticism: an exploratory study across 25 environments by Josefin Werme, Sophie van der Sluis, Danielle Posthuma, Christiaan A. de Leeuw

Published 2021-03-01

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Article
10

Conditional and interaction gene-set analysis reveals novel functional pathways for blood pressure by Christiaan A. de Leeuw, Sven Stringer, Ilona A. Dekkers, Tom Heskes, Danielle Posthuma

Published 2018-09-01

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Article
11

On the interpretation of transcriptome-wide association studies. by Christiaan de Leeuw, Josefin Werme, Jeanne E Savage, Wouter J Peyrot, Danielle Posthuma

Published 2023-09-01

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Article
12

Quantitative proteomic analysis of Rett iPSC-derived neuronal progenitors by Suzy Varderidou-Minasian, Lisa Hinz, Dominique Hagemans, Danielle Posthuma, Maarten Altelaar, Vivi M. Heine

Published 2020-05-01

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Article
13

Rare variant aggregation in 148,508 exomes identifies genes associated with proxy dementia by Douglas P. Wightman, Jeanne E. Savage, Christiaan A. de Leeuw, Iris E. Jansen, Danielle Posthuma

Published 2023-02-01

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Article
14

Exploring the genetic correlations of antisocial behaviour and life history traits by Jorim J. Tielbeek, J.C. Barnes, Arne Popma, Tinca J.C. Polderman, James J. Lee, John R.B. Perry, Danielle Posthuma, Brian B. Boutwell

Published 2018-11-01

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Article
15

Systematic assessment of variability in the proteome of iPSC derivatives by Stephanie D. Beekhuis-Hoekstra, Kyoko Watanabe, Josefin Werme, Christiaan A. de Leeuw, Iryna Paliukhovich, Ka Wan Li, Frank Koopmans, August B. Smit, Danielle Posthuma, Vivi M. Heine

Published 2021-10-01

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Article
16

Author Correction: Genome-wide meta-analysis of brain volume identifies genomic loci and genes shared with intelligence by Philip R. Jansen, Mats Nagel, Kyoko Watanabe, Yongbin Wei, Jeanne E. Savage, Christiaan A. de Leeuw, Martijn P. van den Heuvel, Sophie van der Sluis, Danielle Posthuma

Published 2022-06-01

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Article
17

Genome-wide association study of cerebellar volume provides insights into heritable mechanisms underlying brain development and mental health by Elleke Tissink, Siemon C. de Lange, Jeanne E. Savage, Douglas P. Wightman, Christiaan A. de Leeuw, Kristen M. Kelly, Mats Nagel, Martijn P. van den Heuvel, Danielle Posthuma

Published 2022-07-01

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18

Shared genetic loci between Alzheimer's disease and multiple sclerosis: Crossroads between neurodegeneration and immune system by Vera Fominykh, Alexey A. Shadrin, Piotr P. Jaholkowski, Shahram Bahrami, Lavinia Athanasiu, Douglas P. Wightman, Emil Uffelmann, Danielle Posthuma, Geir Selbæk, Anders M. Dale, Srdjan Djurovic, Oleksandr Frei, Ole A. Andreassen

Published 2023-07-01

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19

Genetic mapping and evolutionary analysis of human-expanded cognitive networks by Yongbin Wei, Siemon C. de Lange, Lianne H. Scholtens, Kyoko Watanabe, Dirk Jan Ardesch, Philip R. Jansen, Jeanne E. Savage, Longchuan Li, Todd M. Preuss, James K. Rilling, Danielle Posthuma, Martijn P. van den Heuvel

Published 2019-10-01

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Article
20

Molecular signatures and cellular diversity during mouse habenula development by Lieke L. van de Haar, Danai Riga, Juliska E. Boer, Oxana Garritsen, Youri Adolfs, Thomas E. Sieburgh, Roland E. van Dijk, Kyoko Watanabe, Nicky C.H. van Kronenburg, Mark H. Broekhoven, Danielle Posthuma, Frank J. Meye, Onur Basak, R. Jeroen Pasterkamp

Published 2022-07-01

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Article

Danielle Posthuma

Genetically-Informed Patient Selection for iPSC Studies of Complex Diseases May Aid in Reducing Cellular Heterogeneity by Stephanie D. Hoekstra, Sven Stringer, Vivi M. Heine, Vivi M. Heine, Danielle Posthuma, Danielle Posthuma

Genome-wide association studies of polygenic risk score-derived phenotypes may lead to inflated false positive rates by Emil Uffelmann, Danielle Posthuma, Wouter J. Peyrot

TATES: efficient multivariate genotype-phenotype analysis for genome-wide association studies. by Sophie van der Sluis, Danielle Posthuma, Conor V Dolan

Phenotypic complexity, measurement bias, and poor phenotypic resolution contribute to the missing heritability problem in genetic association studies. by Sophie van der Sluis, Matthijs Verhage, Danielle Posthuma, Conor V Dolan

MAGMA: generalized gene-set analysis of GWAS data. by Christiaan A de Leeuw, Joris M Mooij, Tom Heskes, Danielle Posthuma

Correction: Genome-wide gene-environment interactions in neuroticism: an exploratory study across 25 environments by Josefin Werme, Sophie van der Sluis, Danielle Posthuma, Christiaan A. de Leeuw

Correction to: Genome-wide gene-environment interactions in neuroticism: an exploratory study across 25 environments by Josefin Werme, Sophie van der Sluis, Danielle Posthuma, Christiaan A. de Leeuw

Item-level analyses reveal genetic heterogeneity in neuroticism by Mats Nagel, Kyoko Watanabe, Sven Stringer, Danielle Posthuma, Sophie van der Sluis

Genome-wide gene-environment interactions in neuroticism: an exploratory study across 25 environments by Josefin Werme, Sophie van der Sluis, Danielle Posthuma, Christiaan A. de Leeuw

Conditional and interaction gene-set analysis reveals novel functional pathways for blood pressure by Christiaan A. de Leeuw, Sven Stringer, Ilona A. Dekkers, Tom Heskes, Danielle Posthuma

On the interpretation of transcriptome-wide association studies. by Christiaan de Leeuw, Josefin Werme, Jeanne E Savage, Wouter J Peyrot, Danielle Posthuma

Quantitative proteomic analysis of Rett iPSC-derived neuronal progenitors by Suzy Varderidou-Minasian, Lisa Hinz, Dominique Hagemans, Danielle Posthuma, Maarten Altelaar, Vivi M. Heine

Rare variant aggregation in 148,508 exomes identifies genes associated with proxy dementia by Douglas P. Wightman, Jeanne E. Savage, Christiaan A. de Leeuw, Iris E. Jansen, Danielle Posthuma

Exploring the genetic correlations of antisocial behaviour and life history traits by Jorim J. Tielbeek, J.C. Barnes, Arne Popma, Tinca J.C. Polderman, James J. Lee, John R.B. Perry, Danielle Posthuma, Brian B. Boutwell

Systematic assessment of variability in the proteome of iPSC derivatives by Stephanie D. Beekhuis-Hoekstra, Kyoko Watanabe, Josefin Werme, Christiaan A. de Leeuw, Iryna Paliukhovich, Ka Wan Li, Frank Koopmans, August B. Smit, Danielle Posthuma, Vivi M. Heine

Author Correction: Genome-wide meta-analysis of brain volume identifies genomic loci and genes shared with intelligence by Philip R. Jansen, Mats Nagel, Kyoko Watanabe, Yongbin Wei, Jeanne E. Savage, Christiaan A. de Leeuw, Martijn P. van den Heuvel, Sophie van der Sluis, Danielle Posthuma

Genetic mapping and evolutionary analysis of human-expanded cognitive networks by Yongbin Wei, Siemon C. de Lange, Lianne H. Scholtens, Kyoko Watanabe, Dirk Jan Ardesch, Philip R. Jansen, Jeanne E. Savage, Longchuan Li, Todd M. Preuss, James K. Rilling, Danielle Posthuma, Martijn P. van den Heuvel

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